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Title Sort ascending	Pub Year	Author	SearchLink
Long-term study of migration of volatile organic compounds from cross-linked polyethylene (PEX) pipes and effects on drinking water quality	2011	Division of Environmental Medicine, Department of Water Hygiene, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO-0403 Oslo, Norway. vidar.lund@fhi.no	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of water and health Periodical, Abbrev. J.Water.Health. Pub Date Free Form Sep Volume 9 Issue 3 Start Page 483 Other Pages 497 Notes LR: 20121115; JID: 101185420; 0 (Drinking Water); 0 (Methyl Ethers); 0 (Volatile Organic Compounds); 0 (Water Pollutants, Chemical); 29I4YB3S89 (methyl tert-butyl ether); 9002-88-4 (Polyethylene); ppublish Place of Publication England ISSN/ISBN 1477-8920; 1477-8920 Accession Number PMID: 21976195 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.2166/wh.2011.165 [doi] Output Language Unknown(0) PMID 21976195 Abstract The objectives of this study were to investigate migration of volatile organic compounds (VOCs) from cross-linked polyethylene (PEX) pipes used for drinking water produced by different production methods, and to evaluate their potential risk for human health and/or influence on aesthetic drinking water quality. The migration tests were carried out in accordance with EN-1420-1, and VOCs were analysed by gas chromatography-mass spectrometry. The levels of VOC migrating from new PEX pipes were generally low, and decreasing with time of pipe use. No association was found between production method of PEX pipes and concentration of migration products. 2,4-di-tert-butyl phenol and methyl tert-butyl ether (MTBE) were two of the major individual components detected. In three new PEX pipes, MTBE was detected in concentrations above the recommended US EPA taste and odour value for drinking water, but decreased below this value after 5 months in service. However, the threshold odour number (TON) values for two pipes were similar to new pipes even after 1 year in use. For seven chemicals for which conclusions on potential health risk could be drawn, this was considered of no or very low concern. However, odour from some of these pipes could negatively affect drinking water for up to 1 year. Descriptors Links Book Title Database Publisher Data Source Authors Lund,V., Anderson-Glenna,M., Skjevrak,I., Steffensen,I.L. Original/Translated Title URL Date of Electronic PMCID Editors
Long-term prognostic effect of coronary atherosclerotic burden: validation of the computed tomography-Leaman score	2015	From the Centro Cardiologico Monzino, IRCCS, Milan, Italy (S.M., G.P., A.L.B., E.B., M.P., D.A.); Cardiology Department, Hospital de Santa Cruz, CHLO, Lisbon, Portugal (P.D.A.G.); Cardiovascular Center, Hospital da Luz, ESS, Lisbon, Portugal (P.D.A.G.); C	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Circulation.Cardiovascular imaging Periodical, Abbrev. Circ.Cardiovasc.Imaging Pub Date Free Form Feb Volume 8 Issue 2 Start Page e002332 Other Pages Notes CI: (c) 2014; JID: 101479935; CIN: Circ Cardiovasc Imaging. 2015 Feb;8(2):e003081. PMID: 25666718; OTO: NOTNLM; ppublish Place of Publication United States ISSN/ISBN 1942-0080; 1941-9651 Accession Number PMID: 25666717 Language eng SubFile Journal Article; Validation Studies; IM DOI 10.1161/CIRCIMAGING.114.002332 [doi] Output Language Unknown(0) PMID 25666717 Abstract BACKGROUND: Computed tomography-adapted Leaman score (CT-LeSc) was developed to quantify coronary CT angiography information about atherosclerotic burden (lesion localization, stenosis degree, and plaque composition). The objective of the study is to evaluate CT-LeSc long-term prognostic value in patients with suspected coronary artery disease (CAD). METHODS AND RESULTS: Single-center prospective registry including 1304 consecutive patients undergoing coronary CT angiography for suspected CAD. High CT-LeSc was defined by upper tertile (score, >5) cutoff. Segment involvement score and segment stenosis score were also evaluated. Hard cardiac events (cardiac death and nonfatal acute coronary syndromes) were considered for analysis. Different Cox regression models were used to identify independent event predictors. Kaplan-Meier event-free survival was evaluated in 4 patient subgroups stratified by obstructive (>/=50% stenosis) versus nonobstructive CAD and a high (>5) versus a low (=5) CT-LeSc. Of 1196 patients included in the final analysis (mean follow-up of 52+/-22 months), 125 patients experienced 136 hard events (18 cardiac deaths and 118 nonfatal myocardial infarction). All atherosclerotic burden scores were independent predictors of cardiac events (hazard ratios of 3.09 for segment involvement score, 4.42 for segment stenosis score, and 5.39 for CT-LeSc). Cumulative event-free survival was 76.8% with a high CT-LeSc and 96.0% with a low CT-LeSc. Event-free survival in nonobstructive CAD with high CT-LeSc (78.6%) was similar to obstructive CAD with high CT-LeSc (76.5%) but lower than obstructive CAD with low CT-LeSc (80.7%). CONCLUSIONS: CT-LeSc is an independent long-term predictor of hard cardiac events. Patients with nonobstructive CAD and high CT-LeSc had hard event-free survival similar to patients with obstructive CAD. Descriptors Links Book Title Database Publisher American Heart Association, Inc Data Source Authors Mushtaq,S., De Araujo Goncalves,P., Garcia-Garcia,H.M., Pontone,G., Bartorelli,A.L., Bertella,E., Campos,C.M., Pepi,M., Serruys,P.W., Andreini,D. Original/Translated Title URL Date of Electronic PMCID Editors
Long-term monitoring of atmospheric deposition and the implications of ionic inputs for the sustainability of a coniferous forest ecosystem	2001	Farrell, E.P., Forest Ecosystem Research Group, Faculty of Agriculture, University College Dublin, Dublin 4, Ireland	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Water, air, and soil pollution Periodical, Abbrev. Water Air Soil Pollut. Pub Date Free Form 2001/ Volume 130 Issue 1-4 III Start Page 1055 Other Pages 1060 Notes Place of Publication ISSN/ISBN 0049-6979 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Ionic fluxes in a semi-mature stand of Sitka spruce (Picea sitchensis (Bong.) Carr.), on a spodosol in eastern Ireland, were monitored over an eight-year period, 1991-1998. The paper focuses on the long-term viability of forests in this region. Input-output balances, proton budgets and critical loads suggest that the long-term sustainability of forests in the region is threatened unless atmospheric emissions of anthropogenic substances can be controlled. Descriptors ion, proton, article, atmospheric transport, controlled study, ecosystem, environmental management, environmental monitoring, environmental protection, forest, ion transport, Ireland, nonhuman, plant Links Book Title Database Embase Publisher Data Source Embase Authors Farrell,E. P., Aherne,J., Boyle,G. M., Nunan,N. Original/Translated Title URL Date of Electronic PMCID Editors
Long-term exposure of Sitka spruce seedlings to trichloroacetic acid	2003	Cape, J.N., Centre for Ecology and Hydrology, Penicuik, Midlothian EH26 OQB, United Kingdom	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Environmental Science and Technology Periodical, Abbrev. Environ.Sci.Technol. Pub Date Free Form 2003/07 Volume 37 Issue 13 Start Page 2953 Other Pages 2957 Notes Place of Publication ISSN/ISBN 0013-936X Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Trichloroacetic acid (TCA) has been implicated as an airborne pollutant responsible for adverse effects on forest health. There is considerable debate as to whether TCA observed in trees and forest soils is derived from atmospheric deposition or from in situ production. This experiment reports the results from treating 4-year-old Sitka spruce (Picea sitchensis (Bong.) Carr) plants in a greenhouse over a growing season with TCA supplied either to the soil or to the foliage at concentrations of 10 and 100 ng mL-1. Similar uptake of TCA by needles was observed for both modes of treatment, with significant accumulation of TCA (300 ng g-1 dry wt) at the higher concentration. Larger concentrations in stem tissue were seen for the foliar-applied TCA (280 ng g-1) than for the soil-applied TCA (70 ng g-1), suggesting that direct stem uptake may be important. Six months after treatments stopped, TCA concentrations in the needles of plants exposed to 100 ng mL-1 TCA were still enhanced, showing that biological degradation of TCA in needles was slow over the winter. By contrast, no significant enhancement of TCA in soil could be detected in the directly treated soils even during the experiment. The protein content of needles treated with the higher concentration of TCA by either route was significantly smaller than for the controls, but there was no effect of TCA on the conjugation of 1-chloro-2,4-dinitrobenzene in roots nor on the conjugation of 1,2-dichloro-4-nitrobenzene in needles. Descriptors 1 chloro 2,4 dinitrobenzene, 1,2 dichloro 4 nitrobenzene, trichloroacetic acid, air pollutant, air pollution, article, atmospheric deposition, biodegradation, concentration (parameters), conjugation, controlled study, foliage, forest, forest soil, greenhouse, long term exposure, nonhuman, plant growth, plant root, plant stem, pollution transport, protein content, seedling, sitka spruce, winter Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Cape,J. N., Reeves,N. M., SchrÃ¶der,P., Heal,M. R. Original/Translated Title URL Date of Electronic PMCID Editors
Long bone histology of the stem salamander Kokartus honorarius (Amphibia: Caudata) from the Middle Jurassic of Kyrgyzstan	2015	Vertebrate Zoology Department, Biological Faculty, Saint Petersburg State University, Saint Petersburg, Russian Federation.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of anatomy Periodical, Abbrev. J.Anat. Pub Date Free Form Apr Volume 226 Issue 4 Start Page 334 Other Pages 347 Notes CI: (c) 2015; JID: 0137162; OTO: NOTNLM; 2015/01/05 [accepted]; 2015/02/12 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-7580; 0021-8782 Accession Number PMID: 25682890 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1111/joa.12281 [doi] Output Language Unknown(0) PMID 25682890 Abstract Kokartus honorarius from the Middle Jurassic (Bathonian) of Kyrgyzstan is one of the oldest salamanders in the fossil record, characterized by a mixture of plesiomorphic morphological features and characters shared with crown-group salamanders. Here we present a detailed histological analysis of its long bones. The analysis of a growth series demonstrates a significant histological maturation during ontogeny, expressed by the progressive appearance of longitudinally oriented primary vascular canals, primary osteons, growth marks, remodelling features in primary bone tissues, as well as progressive resorption of the calcified cartilage, formation of endochondral bone and development of cartilaginous to bony trabeculae in the epiphyses. Apart from the presence of secondary osteons, the long bone histology of Kokartus is very similar to that of miniaturized temnospondyls, other Jurassic stem salamanders, miniaturized seymouriamorphs and modern crown-group salamanders. We propose that the presence of secondary osteons in Kokartus honorarius is a plesiomorphic feature, and the loss of secondary osteons in the long bones of crown-group salamanders as well as in those of miniaturized temnospondyls is the result of miniaturization processes. Hitherto, all stem salamander long bong histology (Kokartus, Marmorerpeton and 'salamander A') has been generally described as having paedomorphic features (i.e. the presence of Katschenko's Line and a layer of calcified cartilage), these taxa were thus most likely neotenic forms. The absence of clear lines of arrested growth and annuli in long bones of Kokartus honorarius suggests that the animals lived in an environment with stable local conditions. Descriptors Links Book Title Database Publisher Anatomical Society Data Source Authors Skutschas,P., Stein,K. Original/Translated Title URL Date of Electronic 20150212 PMCID Editors
Local domestication of lactic acid bacteria via cassava beer fermentation	2014	Department of Anthropology, University of Oregon , Eugene, OR , USA ; Institute of Ecology and Evolution, University of Oregon , Eugene, OR , USA.; Institute of Ecology and Evolution, University of Oregon , Eugene, OR , USA.; Department of Anthropology, U	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PeerJ Periodical, Abbrev. PeerJ Pub Date Free Form 8-Jul Volume 2 Issue Start Page e479 Other Pages Notes LR: 20140731; JID: 101603425; OID: NLM: PMC4103073; OTO: NOTNLM; 2014 [ecollection]; 2014/02/02 [received]; 2014/06/18 [accepted]; 2014/07/08 [epublish]; epublish Place of Publication United States ISSN/ISBN 2167-8359 Accession Number PMID: 25071997 Language eng SubFile Journal Article DOI 10.7717/peerj.479 [doi] Output Language Unknown(0) PMID 25071997 Abstract Cassava beer, or chicha, is typically consumed daily by the indigenous Shuar people of the Ecuadorian Amazon. This traditional beverage made from cassava tuber (Manihot esculenta) is thought to improve nutritional quality and flavor while extending shelf life in a tropical climate. Bacteria responsible for chicha fermentation could be a source of microbes for the human microbiome, but little is known regarding the microbiology of chicha. We investigated bacterial community composition of chicha batches using Illumina high-throughput sequencing. Fermented chicha samples were collected from seven Shuar households in two neighboring villages in the Morona-Santiago region of Ecuador, and the composition of the bacterial communities within each chicha sample was determined by sequencing a region of the 16S ribosomal gene. Members of the genus Lactobacillus dominated all samples. Significantly greater phylogenetic similarity was observed among chicha samples taken within a village than those from different villages. Community composition varied among chicha samples, even those separated by short geographic distances, suggesting that ecological and/or evolutionary processes, including human-mediated factors, may be responsible for creating locally distinct ferments. Our results add to evidence from other fermentation systems suggesting that traditional fermentation may be a form of domestication, providing endemic beneficial inocula for consumers, but additional research is needed to identify the mechanisms and extent of microbial dispersal. Descriptors Links Book Title Database Publisher Data Source Authors Colehour,A.M., Meadow,J.F., Liebert,M.A., Cepon-Robins,T.J., Gildner,T.E., Urlacher,S.S., Bohannan,B.J., Snodgrass,J.J., Sugiyama,L.S. Original/Translated Title URL Date of Electronic 20140708 PMCID PMC4103073 Editors
Little Cigars and Cigarillos: Users, Perceptions, and Reasons for Use	2016	Research Consultant, Tobacco Center of Regulatory Science (TCORS), School of Public Health, Georgia State University, Atlanta, GA.; Associate Professor, Division of Health Promotion & Behavior, School of Public Health, Georgia State University, Atlanta, G	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco regulatory science Periodical, Abbrev. Tob Regul.Sci. Pub Date Free Form Jul Volume 2 Issue 3 Start Page 239 Other Pages 251 Notes LR: 20160717; GR: P50 DA036128/DA/NIDA NIH HHS/United States; JID: 101655763; NIHMS791953; OTO: NOTNLM; 2016/07/01 [epublish]; ppublish Place of Publication ISSN/ISBN 2333-9748; 2333-9748 Accession Number PMID: 27413772 Language ENG SubFile JOURNAL ARTICLE DOI 10.18001/TRS.2.3.4 [doi] Output Language Unknown(0) PMID 27413772 Abstract OBJECTIVE: This study examines little cigar and cigarillo (LCC) adult user characteristics, perceived addictiveness, use and importance of flavors, intentions to continue use, and reasons for use to inform prevention efforts and regulatory policy. METHODS: Data come from the 2014 Tobacco Products and Risk Perceptions Survey of a national probability sample of 5717 US adults, conducted online, June-November, 2014. The analytic sample consisted of 141 current LCC users. RESULTS: Current LCC smokers were more likely to be male, younger, black or Hispanic, lower SES, current cigarette smokers, and to report poorer health than non-smokers. Perceived addictiveness was low overall, with 73.6% considering themselves "not at all" addicted, although female LCC users and dual users of cigarettes were more likely to consider themselves addicted to LCCs. Use of flavored LCCs was widespread. Flavors were cited as important reasons for use, especially among younger users, as were favorable comparisons with affordability and burn time of cigarettes. CONCLUSIONS: Most LCC users do not perceive themselves addicted to LCCs. Users report being influenced most by flavorings and affordability, indicating that appropriate regulations and education to improve health perceptions could help reduce use of these harmful products. Descriptors Links Book Title Database Publisher Data Source Authors Nyman,A.L., Sterling,K.L., Weaver,S.R., Majeed,B.A., Eriksen,M.P. Original/Translated Title URL Date of Electronic 20160701 PMCID PMC4939836 Editors
Litiasis fosa navicular de uretra	2005		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Arch Esp Urol Periodical, Abbrev. Arch.Esp.Urol. Pub Date Free Form Volume 58 Issue 10 Start Page 1070 Other Pages 2 Notes ID: 16482860 Place of Publication ISSN/ISBN Accession Number Language es SubFile DOI Output Language Unknown(0) PMID Abstract OBJECTIVE: Evaluate the treatment of the meatus urethral lithiasis. METHODS/RESULTS: A case of a 52 year-old male patient is reported with a big stone in the urethral meatus. Male patient that consults for Micturitional Syndrome, disury and difficully when urinating, in whom felt induration of the glans and observed a water-pipe where the patient urinated. The Diagnoses was made by the observation and the palpation of the glans. It was extracted by meatoplasthy with good results. CONCLUSIONS: The treatment of the meatus urethral big lithiasis that causes obstruction is the meatoplasthy. Descriptors Urethral Diseases, Urinary Calculi, Humans, Male, Middle Aged, Urethral Diseases/diagnosis, Urethral Diseases/therapy, Urinary Calculi/diagnosis, Urinary Calculi/therapy Links http://pesquisa.bvsalud.org/ghl/resource/en/mdl-16482860 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Granados Loarca,Edgar Antonio, Salazar Monterroso,Carlos, Robles,Carlos Original/Translated Title URL Date of Electronic PMCID Editors
Liquid crystal precursor mucoadhesive system as a strategy to improve the prophylactic action of Syngonanthus nitens (Bong.) Ruhland against infection by Candida krusei	2015	Department of Biological Sciences, School of Pharmaceutical Sciences, Sao Paulo State University, Araraquara, Brazil.; Department of Drugs and Medicine, School of Pharmaceutical Sciences, Sao Paulo State University, Araraquara, Brazil.; Department of Infe	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of nanomedicine Periodical, Abbrev. Int.J.Nanomedicine Pub Date Free Form 16-Dec Volume 10 Issue Start Page 7455 Other Pages 7466 Notes LR: 20160102; JID: 101263847; OID: NLM: PMC4687718; OTO: NOTNLM; 2015 [ecollection]; 2015/12/16 [epublish]; epublish Place of Publication New Zealand ISSN/ISBN 1178-2013; 1176-9114 Accession Number PMID: 26719688 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.2147/IJN.S92638 [doi] Output Language Unknown(0) PMID 26719688 Abstract Vaginal infections caused by Candida krusei are a problem of extreme complexity due to the intrinsic resistance to azole drugs. The species Syngonanthus nitens (Bong.) Ruhland is a plant of the Eriocaulaceae family that has demonstrated promising antifungal activity. In phyto-formulation research, liquid crystal precursor mucoadhesive systems (LCPM) stand out as drug delivery systems for vaginal administration because they increase the activity and overcome the problems associated with plant-based medicines. Therefore, the objective of this study was to evaluate the potential of the methanolic extract of scapes of S. nitens (S. nitens extract [SNE]) and an SNE-loaded LCPM against C. krusei as prophylaxis for vulvovaginal candidiasis. LCPM formulation developed consisted of oleic acid as the oil phase (50% w/w), polyoxypropylene (5) polyoxyethylene (20) cetyl alcohol (40% w/w) as the surfactant and a polymeric dispersion containing 2.5% Carbopol((R)) 974P and 2.5% polycarbophil (10% w/w) as the aqueous phase. LCPM formulation developed was characterized using polarized light microscopy, rheological analysis, and in vitro mucoadhesive studies. Different strains of C. krusei, including one standard strain (American Type Culture Collection 6258) and three clinically isolated strains from the vaginal region (CKV1, 2, and 3), were used to determine the minimum inhibitory concentration, inhibition of biofilms, and time kill. The in vivo prophylaxis assay was performed using the standard strain (American Type Culture Collection 6258). The analyses of F by polarized light microscopy and rheology showed isotropy; however, the addition of 100% artificial vaginal mucus (F100) made it more viscous and anisotropic. Moreover, the mucoadhesive strength was modified, which makes F an excellent formulation for vaginal applications. SNE was active against all strains studied, with minimum inhibitory concentration values ranging from 125 to 62.5 microg/mL; after incorporating SNE into F (FE), these values decreased to 62.5 to 31.2 microg/mL, demonstrating that incorporation into the formulation potentiated the action of SNE. Additionally, the time kill assays showed that both forms of SNE were capable of controlling growth, thereby suggesting a possible fungistatic mechanism. Unloaded SNE was not active against C. krusei biofilms, but FE was active against a clinical strain (CKV2). In vivo analysis showed that FE was able to prevent the development of infection following 10 days of administration. We concluded that the formulation developed in this study was an important vehicle for the delivery of SNE based on the improved antifungal activity in all in vitro and in vivo analyses. Furthermore, the extract incorporated into the system may serve as an important prophylactic agent against vaginal infections caused by C. krusei. Descriptors Links Book Title Database Publisher Data Source Authors dos Santos Ramos,M.A., Calixto,G., de Toledo,L.G., Bonifacio,B.V., dos Santos,L.C., de Almeida,M.T., Chorilli,M., Bauab,T.M. Original/Translated Title URL Date of Electronic 20151216 PMCID PMC4687718 Editors
Liposomal amphotericin B displays rapid dose-dependent activity against Candida albicans biofilms	2013	Infection and Immunity Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom. gordon.ramage@glasgow.ac.uk	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form May Volume 57 Issue 5 Start Page 2369 Other Pages 2371 Notes LR: 20150219; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Pyrimidines); 0 (Triazoles); 0 (liposomal amphotericin B); 7XU7A7DROE (Amphotericin B); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole); OID: NLM: PMC3632906; 2013/02/19 [aheadof Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 23422915 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AAC.02344-12 [doi] Output Language Unknown(0) PMID 23422915 Abstract Biofilms formed by Candida albicans bloodstream isolates on catheters are an important clinical problem. Devising chemotherapeutic strategies to treat these in situ is an attractive option. We report here that liposomal amphotericin effectively kills C. albicans biofilms rapidly (12 h) and effectively (>90%) in a dose-dependent manner, whereas caspofungin displays an inverse concentration-dependent effect. This study has implications for considering the effective doses of antifungal agents used for catheter lock therapy. Descriptors Links Book Title Database Publisher Data Source Authors Ramage,G., Jose,A., Sherry,L., Lappin,D.F., Jones,B., Williams,C. Original/Translated Title URL Date of Electronic 20130219 PMCID PMC3632906 Editors

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