WTS database

Title Sort descending	Pub Year	Author	SearchLink
Imported chicken meat as a potential source of quinolone-resistant Escherichia coli producing extended-spectrum beta-lactamases in the UK	2008	Microbiology Laboratory, Shrewsbury and Telford Hospital NHS Trust, Shrewsbury SY3 8XQ, UK. roderic.warren@homecall.co.uk	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of antimicrobial chemotherapy Periodical, Abbrev. J.Antimicrob.Chemother. Pub Date Free Form Mar Volume 61 Issue 3 Start Page 504 Other Pages 508 Notes JID: 7513617; EC 3.5.2.6 (beta-Lactamases); 2008/01/25 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1460-2091; 0305-7453 Accession Number PMID: 18222958 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/jac/dkm517 [doi] Output Language Unknown(0) PMID 18222958 Abstract OBJECTIVES: Escherichia coli producing CTX-M-15 enzyme began to rapidly spread in the UK from around 2003 but other types also occur, notably CTX-M-14. We examined breasts from UK-reared (n = 62) and imported (n = 27) chickens as potential sources of quinolone-resistant E. coli with bla(CTX-M) genes. A further 40 samples for which the country of rearing could not be identified were examined. METHODS: During 2006, 129 fresh and frozen chicken breast fillets were purchased from retail outlets in the West Midlands. These were cultured for E. coli on CLED agar containing 8 mg/L ciprofloxacin and carrying a 10 microg cefpodoxime disc. Resistant isolates were identified and typed by RAPD fingerprinting; bla(CTX-M) was identified by PCR and genotyped by reverse-line hybridization. RESULTS: The country of rearing was identified from the packaging for 89 of 129 purchased samples. Only one of the 62 UK-reared chicken samples carried E. coli producing a CTX-M-1 enzyme, whereas 10 of 27 samples reared overseas had E. coli with CTX-M enzymes. Specifically, 4/10 Brazilian, 3/4 Brazilian/Polish/French, and 2/2 Dutch samples had E. coli with CTX-M-2 enzymes. Six of 40 samples for which the country of rearing was not known had producers of CTX-M enzymes, 5 of them with CTX-M-14. CONCLUSIONS: Quinolone-resistant E. coli with various CTX-M beta-lactamase genes that are common in human infections worldwide were found in imported chicken breasts, indicating a possible source for gut colonization. Samples from Brazil were commonly positive for E. coli with CTX-M-2, the dominant bla(CTX-M) genotype from human infections in South America, which is currently rare in clinical infections in the UK. CTX-M-15, the dominant CTX-M type in human infections in the UK, was not found in chicken isolates, suggesting that the UK-reared chickens are not a reservoir of CTX-M-15. Descriptors Animals, Brazil, Chickens, Drug Resistance, Bacterial/physiology, Escherichia coli/enzymology/isolation & purification, Escherichia coli Infections/microbiology/prevention & control, Europe, Food Contamination/analysis/prevention & control, Food Microbiology, Great Britain, Meat/microbiology, beta-Lactamases/biosynthesis/isolation & purification Links Book Title Database Publisher Data Source Authors Warren,R. E., Ensor,V. M., O'Neill,P., Butler,V., Taylor,J., Nye,K., Harvey,M., Livermore,D. M., Woodford,N., Hawkey,P. M. Original/Translated Title URL Date of Electronic 20080125 PMCID Editors
Improvement of the state of municipal and industrial waste water pipes by active and passive corrosion prevention	1980	Bauakad. DDR, Inst. Ingenieur- und Tiefbau, Leipzig	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Wasserwirtschaft Wassertechnik Periodical, Abbrev. WASSERWIRTSCH.WASSERTECHN. Pub Date Free Form 1980/ Volume 30 Issue 10 Start Page 345 Other Pages 348 Notes Place of Publication ISSN/ISBN 0043-0986 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors corrosion, industry, prevention, sewage treatment, therapy, waste water management Links Book Title VERBESSERUNG DES ZUSTANDES KOMMUNALER UND INDUSTRIELLER ABWASSERNETZE DURCH AKTIVEN UND PASSIVEN KORROSIONSSCHUTZ Database Embase Publisher Data Source Embase Authors Mueller,W., Greschuchna,R. Original/Translated Title URL Date of Electronic PMCID Editors
In reply	2015		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Deutsches Arzteblatt international Periodical, Abbrev. Dtsch.Arztebl Int. Pub Date Free Form 27-Mar Volume 112 Issue 13 Start Page 221 Other Pages Notes LR: 20151111; JID: 101475967; CON: Dtsch Arztebl Int. 2014 Oct 3;111(40):674-9. PMID: 25346357; CON: Dtsch Arztebl Int. 2015 Mar 27;112(13):221. PMID: 25869342; OID: NLM: PMC4453467; ppublish Place of Publication Germany ISSN/ISBN 1866-0452; 1866-0452 Accession Number PMID: 25869343 Language eng SubFile Comment; Letter; IM DOI 10.3238/arztebl.2015.0221b [doi] Output Language Unknown(0) PMID 25869343 Abstract Descriptors Links Book Title Database Publisher Data Source Authors von Rappard,J. Original/Translated Title URL Date of Electronic PMCID PMC4453467 Editors
In situ hydrothermal growth of ytterbium-based metal-organic framework on stainless steel wire for solid-phase microextraction of polycyclic aromatic hydrocarbons from environmental samples	2015	College of Food Science and Engineering, Shandong Agricultural University, Taian, China; Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Analysis and Test Center, Shandong Academy of Sciences, Jinan, Chi	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 9-Oct Volume 1415 Issue Start Page 11 Other Pages 19 Notes CI: Copyright (c) 2015; JID: 9318488; 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Soil Pollutants); 0 (Waste Water); 0 (Water Pollutants, Chemical); 12597-68-1 (Stainless Steel); MNQ4O4WSI1 (Ytterbium); OTO: NOTNLM; 2015/06/29 [received]; 2015/08/17 [revise Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 26346186 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2015.08.036 [doi] Output Language Unknown(0) PMID 26346186 Abstract In this paper, we report the use of a porous ytterbium-based metal-organic framework (Yb-MOF) coating material with good thermal stability for the headspace solid-phase microextraction (HS-SPME) of polycyclic aromatic hydrocarbons (PAHs) from environmental samples. The Yb-MOF thin films, grown in situ on stainless steel wire in solution, exhibited high selectivity and sensitivity toward PAHs. Under the optimal conditions, the novel fibers achieved large enrichment factors (130-2288), low limits of detection (0.07-1.67ngL(-1)), and wide range of linearity (10-1000ngL(-1)) for 16 PAHs in the tested samples. The novel fiber was successfully used in the analysis of PAHs in real environmental samples. These results demonstrated that Yb-MOF is a promising coating material for the SPME of PAHs at trace levels from environmental samples. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Li,Q.L., Wang,X., Chen,X.F., Wang,M.L., Zhao,R.S. Original/Translated Title URL Date of Electronic 20150821 PMCID Editors
In vitro activities of anidulafungin and other antifungal agents against biofilms formed by clinical isolates of different Candida and Aspergillus species	2011	Istituto di Microbiologia, Universita Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Jun Volume 55 Issue 6 Start Page 3031 Other Pages 3035 Notes LR: 20150204; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 9HLM53094I (anidulafungin); F0XDI6ZL63 (caspofungin); OID: NLM: PMC3101406; 2011/03/21 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 21422210 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AAC.01569-10 [doi] Output Language Unknown(0) PMID 21422210 Abstract We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(9)(0)s (SMIC(9)(0)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(9)(0)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(9)(0) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins. Descriptors Links Book Title Database Publisher Data Source Authors Fiori,B., Posteraro,B., Torelli,R., Tumbarello,M., Perlin,D.S., Fadda,G., Sanguinetti,M. Original/Translated Title URL Date of Electronic 20110321 PMCID PMC3101406 Editors
In vitro activities of antifungal combinations against biofilms and planktonic forms of clinical Trichosporon asahii isolates	2014	Department of Dermatology, General Hospital of Beijing Military Command, Beijing, People's Republic of China.; Department of Dermatology, General Hospital of Beijing Military Command, Beijing, People's Republic of China.; Department of Dermatology, Genera	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Dec Volume 58 Issue 12 Start Page 7615 Other Pages 7616 Notes LR: 20151029; JID: 0315061; 0 (Antifungal Agents); 0 (Drug Combinations); 0 (Echinocandins); 7XU7A7DROE (Amphotericin B); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole); OID: NLM: PMC4249521; 2014/09/22 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1098-6596; 0066-4804 Accession Number PMID: 25246408 Language eng SubFile Letter; Research Support, Non-U.S. Gov't; IM DOI 10.1128/AAC.03817-14 [doi] Output Language Unknown(0) PMID 25246408 Abstract Descriptors Links Book Title Database Publisher Data Source Authors Liao,Y., Yang,S., Cong,L., Lu,X., Ao,J., Yang,R. Original/Translated Title URL Date of Electronic 20140922 PMCID PMC4249521 Editors
In vitro activity of amphotericin B and anidulafungin against Candida spp. biofilms	2007	Unidad de Microbiologia Experimental, Centro Investigacion, Hospital Universitario La Fe, Valencia, Spain.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Revista Iberoamericana De Micologia Periodical, Abbrev. Rev.Iberoam.Micol. Pub Date Free Form 31-Dec Volume 24 Issue 4 Start Page 272 Other Pages 277 Notes LR: 20131121; JID: 9425531; 0 (Antifungal Agents); 0 (Echinocandins); 7XU7A7DROE (Amphotericin B); 9HLM53094I (anidulafungin); ppublish Place of Publication Spain ISSN/ISBN 1130-1406; 1130-1406 Accession Number PMID: 18095759 Language spa SubFile Comparative Study; English Abstract; Journal Article; IM DOI 200724272 [pii] Output Language Unknown(0) PMID 18095759 Abstract Invasive infections caused by Candida spp. are increasing worldwide and are becoming an important cause of morbidity and mortality in immunocompromised patients. A large number of manifestations of candidiasis are associated with the formation of biofilms on inert or biological surfaces. Candida spp. biofilms are recalcitrant to treatment with conventional antifungal therapies. The aim of this study was dual 1) to determine the prevalence of biofilm producers among clinical isolates from catheter (16 C. albicans ) and blood culture (2 C. albicans and 30 C. tropicalis), and 2) to determine the activity of amphotericin B and anidulafungin against C. albicans and C. tropicalis biofilms of 24 and 48 hours of maturation. Biofilms were developed using a 96-well microtitre plate model and production and activity of antifungal agents against biofilms were determined by the tetrazolium (XTT) reduction assay. Of catheter and blood isolates, 62.5 and 56.25%, respectively, produced biofilms. By species, 68.42% of C. albicans and 53.33% of C. tropicalis were biofilm producers. C. albicans biofilms showed more resistance to amphotericin B and anidulafungin than their planktonic counterparts. Complete killing of biofilms was never achieved, even at the highest concentrations of the drugs tested. Anidulafungin displayed more activity than amphotericin B against C. albicans biofilms of 24 hours of maturation (GM MIC 0.354 vs. 0.686 microg/ml), but against C. tropicalis biofilms amphotericin B was more active (GM MIC 11.285 vs. 0.476 microg/ml). In contrast, against biofilms with 48 hours maturation, amphotericin B was more active against both species. Descriptors Amphotericin B/pharmacology, Antifungal Agents/pharmacology, Biofilms/drug effects, Candida albicans/drug effects/physiology, Candida tropicalis/drug effects/physiology, Drug Evaluation, Preclinical, Drug Resistance, Fungal, Echinocandins/pharmacology, Microbial Sensitivity Tests, Species Specificity Links Book Title Database Publisher Data Source Authors Valentin,A., Canton,E., Peman,J., Quindos,G. Original/Translated Title Actividad in vitro de la anfotericina B y la anidulafungina sobre biopeliculas de Candida albicans y Candida tropicalis URL Date of Electronic PMCID Editors
In vitro activity of antifungal combinations against Candida albicans biofilms	2010	Department of Internal Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Wahringer Gurtel 18-20, 1090 Vienna, Austria.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of antimicrobial chemotherapy Periodical, Abbrev. J.Antimicrob.Chemother. Pub Date Free Form Feb Volume 65 Issue 2 Start Page 271 Other Pages 274 Notes LR: 20131125; JID: 7513617; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Triazoles); 6TK1G07BHZ (posaconazole); 7XU7A7DROE (Amphotericin B); F0XDI6ZL63 (caspofungin); 2009/12/08 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1460-2091; 0305-7453 Accession Number PMID: 19996142 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1093/jac/dkp429 [doi] Output Language Unknown(0) PMID 19996142 Abstract OBJECTIVES: The aim of the present study was to evaluate the in vitro activity and synergism of the combinations of amphotericin B/caspofungin and amphotericin B/posaconazole against Candida albicans, grown either as planktonic cells or in biofilms. METHODS: Ten C. albicans bloodstream isolates used in this study were collected from intensive care patients admitted to the Vienna University Hospital between 2006 and 2007. Chequerboard tests were employed to determine the efficacy of the antifungal combinations amphotericin B/caspofungin and amphotericin B/posaconazole against both planktonic cells and biofilms. C. albicans biofilms were prepared using the static microtitre plate model. The activity of antifungal combination therapy was determined by visual reading for planktonic cells and using the XTT assay for biofilms. RESULTS: For Candida biofilms the median MIC was 4 mg/L for amphotericin B and caspofungin, and >256 mg/L for posaconazole. The combination amphotericin B/posaconazole yielded synergism [fractional inhibitory concentration index (FICI) <0.26], whereas amphotericin B/caspofungin yielded indifferent interaction only (FICI 0.75-1.25) against all isolates when grown in biofilms. Under planktonic conditions, synergism was demonstrable for the combination amphotericin B/caspofungin against 4 of the 10 isolates, whereas the combination of caspofungin/posaconazole was indifferent against all tested isolates. CONCLUSIONS: We showed that MICs for planktonic and biofilm forms of C. albicans were much lower when treated with an antifungal combination than when treated with single agents. The combination of amphotericin B/posaconazole yielded synergism against Candida biofilms, whereas amphotericin B/caspofungin yielded indifferent interaction. Descriptors Amphotericin B/pharmacology, Antifungal Agents/pharmacology, Austria, Biofilms/drug effects, Candida albicans/drug effects/isolation & purification, Candidiasis/microbiology, Drug Synergism, Echinocandins/pharmacology, Fungemia/microbiology, Humans, Intensive Care Units, Microbial Sensitivity Tests, Triazoles/pharmacology Links Book Title Database Publisher Data Source Authors Tobudic,S., Kratzer,C., Lassnigg,A., Graninger,W., Presterl,E. Original/Translated Title URL Date of Electronic 20091208 PMCID Editors
In vitro activity of caspofungin against planktonic and sessile Candida sp. cells	2006	Department of Pharmaceutical Microbiology, Medical University of Lublin, Chodiki 1, 20-093 Lublin, Poland.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Polish journal of microbiology / Polskie Towarzystwo Mikrobiologow = The Polish Society of Microbiologists Periodical, Abbrev. Pol.J.Microbiol. Pub Date Free Form Volume 55 Issue 2 Start Page 133 Other Pages 137 Notes LR: 20121115; JID: 101229003; 0 (Antifungal Agents); 0 (Biocompatible Materials); 0 (Echinocandins); 0 (Peptides, Cyclic); 0 (Silicone Elastomers); F0XDI6ZL63 (caspofungin); ppublish Place of Publication Poland ISSN/ISBN 1733-1331; 1733-1331 Accession Number PMID: 17419291 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI Output Language Unknown(0) PMID 17419291 Abstract Candida sp. may be regarded as one of the leading etiologic agents of hospital-acquired infections, including those related with the indwelling medical devices, which become colonized by the yeasts, accompanied by biofilm formation. In this paper we assayed in vitro susceptibility to caspofungin of planktonic and sessile cells of nasopharyngeal isolates of Candida sp. Two types of biomaterials were used - silicone elastomer-coated latex urinary Foley catheter and PCV Thorax catheter. The minimal inhibitory concentrations (MIC) of caspofungin for planktonic Candida sp. cells ranged from 0.008 to 0.031 mg/l, while the minimal fungicidal concentrations (MFC) from 0.008 to 0.062 mg/l, with MFC/MIC ratios 8 mg/l). In all cases, drug concentrations depended on the strain and the biomaterial used. Our preliminary data suggest that caspofungin, showing good anti-adherent activity in vitro against Candida sp., appears to be a potential agent rather for prophylaxis of the yeast infections associated with biomaterials but not for their treatment. Descriptors Antifungal Agents/pharmacology, Biocompatible Materials, Biofilms/drug effects, Candida/drug effects, Cross Infection/prevention & control, Echinocandins, Humans, Microbial Sensitivity Tests/methods, Peptides, Cyclic/pharmacology, Silicone Elastomers Links Book Title Database Publisher Data Source Authors Serefko,A., Chudzik,B., Malm,A. Original/Translated Title URL Date of Electronic PMCID Editors
In vitro activity of caspofungin compared to amphotericin B, fluconazole, and itraconazole against Candida strains isolated in a Turkish University Hospital	2005	Hacettepe University Faculty of Medicine, Department of Microbiology and Clinical Microbiology, Ankara, Turkey. sarikan@metu.edu.tr	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Medical mycology Periodical, Abbrev. Med.Mycol. Pub Date Free Form Mar Volume 43 Issue 2 Start Page 171 Other Pages 178 Notes LR: 20131213; JID: 9815835; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Peptides, Cyclic); 304NUG5GF4 (Itraconazole); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); F0XDI6ZL63 (caspofungin); ppublish Place of Publication England ISSN/ISBN 1369-3786; 1369-3786 Accession Number PMID: 15832560 Language eng SubFile Comparative Study; Journal Article; IM DOI Output Language Unknown(0) PMID 15832560 Abstract We investigated the in vitro activity of caspofungin compared to amphotericin B, fluconazole, and itraconazole against clinical strains of Candida spp. (n =239). Antifungal susceptibility tests were done in accordance with NCCLS M27-A2 microdilution method and the results were read after 24 and 48 h. In general, 24 h MIC readings were similar to those at 48 h for most isolates and all antifungal agents. Caspofungin was active against all species tested. Caspofungin MICs of Candida parapsilosis were slightly higher than those for other Candida spp. Caspofungin MIC (microg/ml) ranges at 24 h for C. albicans, C. glabrata, C tropicalis, C. parapsilosis, C kefyr, C krusei, C. lusitaniae, C. norvegensis, C. guilliermondii and C. lipolytica were 0.06-2, 0.125-2, 0.125-2, 1-4, 0.125-2, 1-2, 0.5-2, 0.5-1, 0.5-2 and 1-2, respectively. Eagle (paradoxical) effect was observed in 31 and 8% of the isolates at highest concentrations of caspofungin and itraconazole, respectively. The activity of caspofungin against fluconazole- and/or itraconazole-resistant isolates was similar to that detected for the susceptible ones. We conclude that caspofungin appears as a promising antifungal agent with enhanced activity against Candida, including the azole-resistant strains. Descriptors Amphotericin B/pharmacology, Antifungal Agents/pharmacology, Candida/drug effects/isolation & purification, Candidiasis/microbiology, Echinocandins, Fluconazole/pharmacology, Hospitals, University, Itraconazole/pharmacology, Microbial Sensitivity Tests, Peptides, Cyclic/pharmacology, Turkey Links Book Title Database Publisher Data Source Authors Arikan,S., Sancak,B., Hascelik,G. Original/Translated Title URL Date of Electronic PMCID Editors

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