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Susceptibility to antifungal agents of Candida sp. and biofilm formation 2011 Katedra i Zaklad Mikrobiologii Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytet Mikolaja Kopernika w Toruniu.
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Journal Article
Periodical, Full
Medycyna doswiadczalna i mikrobiologia
Periodical, Abbrev.
Med.Dosw.Mikrobiol.
Pub Date Free Form
Volume
63
Issue
2
Start Page
171
Other Pages
187
Notes
JID: 0210575; 0 (Antifungal Agents); 0 (Biocompatible Materials); ppublish
Place of Publication
Poland
ISSN/ISBN
0025-8601; 0025-8601
Accession Number
PMID: 22184912
Language
pol
SubFile
English Abstract; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
22184912
Abstract
In recent years the increase in frequency of fungal infections with Candida sp. was noticed. These infections are connected with ability of Candida sp. to form biofilm on surfaces of biomaterials used in medicine. Furthermore fungal infections make serious therapeutic problems because ofbiofilm resistance to antifungal agents actually. The aim of the study was to evaluate the susceptibility to antifungal agents of Candida sp. and their ability to form biofilm on different biomaterials. 50 strains of Candida sp. isolated from patients of University Hospital No. 1 of dr A. Jurasz in Bydgoszcz were examined. API Candida (bioMerieux) tests were used to identify Candida sp. strains. The susceptibility of the yeast strains to antifungal agents was evaluated by ATB FUNGUS 2 INT (bioMerieux) tests. The susceptibility of examined strains to voriconazole, posaconazole, caspofungin and anidulafungin was assessed by means ofEtests (AB BIODISK) method employing drug concentrations from 0,002 to 32 microg/ml. All analysed strains were susceptible to amphotericin B and caspofungin. Biofilm formation on different biomaterials (silicon, latex, polychloride vinyl, polypropylene, nylon) was measured after 72 hour incubation at 37 degrees C. All examined yeasts formed biofilm on all analysed biomaterials. The highest number of strains formed biofilm on surface of polychloride vinyl: 23 (92,0%) by C. albicans strains and 24 (96,0%) Candida non-albicans strains. The lowest number of the strains formed biofilm on the surface of nylon: 12 (48,0%) of C. albicans strains and 9 (36,0%) of Candida non-albicans strains. The studied strains resistant to azoles and anidulafungin display stronger ability to form biofilm on surfaces of all analysed biomaterials.
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Authors
Ciok-Pater,E., Bialucha,A., Gospodarek,E., Ostafin,A.
Original/Translated Title
Lekowrazliwosc a zdolnosc tworzenia biofilmu przez Candida sp
URL
Date of Electronic
PMCID
Editors
Smoking among patients of selected specialist clinics of Miedzylesie Specialist Hospital in Warsaw 2011 Zaklad Pielegniarstwa Klinicznego Wydzialu Nauki o Zdrowiu Warszawskiego Uniwersytetu Medycznego. dpytka@interia.pl
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Print(0)
Ref Type
Journal Article
Periodical, Full
Przeglad lekarski
Periodical, Abbrev.
Przegl.Lek.
Pub Date Free Form
Volume
68
Issue
5
Start Page
243
Other Pages
247
Notes
LR: 20151119; JID: 19840720R; 0 (Tobacco Smoke Pollution); ppublish
Place of Publication
Poland
ISSN/ISBN
0033-2240; 0033-2240
Accession Number
PMID: 21961410
Language
pol
SubFile
English Abstract; Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
21961410
Abstract
The purpose of the study is to examine the issue of smoking among patients of selected clinics of the Miedzylesie Specialist Hospital in Warsaw, assessment of nicotine addiction of smokers and motivation to give up smoking. The survey was carried out in June and July 2009 after obtaining the consent of the Director of Miedzylesie Specialist Hospital in Warsaw. The survey was participated in by 100 patients of selected specialist clinics. The survey was carried out on the basis of a questionnaire consisting of 7 questions. Furthermore, the "Test of motivation to give up smoking" (Schneider's test) and the "Assessment of nicotine addiction level" (Fagerstrom's test), published in the "Consensus regarding recognition and treatment of nicotine addiction", were used. When processing data, the descriptive statistics were applied. Those surveyed included 53 former cigarette smokers 47 active smokers and. In the group of former smokers, 19 people still were exposed to passive smoking. In the past, the problem regarded 41 people. Thirty former smokers smoked cigarettes among non-smokers, including young children (18 people) and when pregnant and breastfeeding (2 people). Also 30 respondents smoked despite medical contraindications and bad conscience. For 27 people, expenditures on cigarettes constituted a considerable burden of their respective household budgets, and 20 said that it was a significant item in their expenditures. Smokers have been smoking cigarettes for 30 years, on average 20 cigarettes a day. Those patients began to smoke at the age of 20. Thirty one active smokers exposed other people to passive smoking and 38 respondents smoked cigarettes despite medical contraindications and with bad conscience. For 22 people, expenditures related to smoking are a considerable burden of the household budget and for 21 people, it is a significant expenditure. Almost one half of the patients smoke cigarettes although they should brake off smoking for medical reasons. Most of those surveyed (32 people) are motivated to brake off smoking. Those people are highly (13 people) and extremely (9 people) addicted to nicotine.
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Data Source
Authors
Pytka,D., Doboszynska,A.
Original/Translated Title
Palenie tytoniu wsrod pacjentow wybranych poradni specjalistycznych Miedzyleskiego Szpitala Specjalistycznego w Warszawie
URL
Date of Electronic
PMCID
Editors
Association of six-minute walk distance (6MWD) with resting pulmonary function in patients with chronic obstructive pulmonary disease (COPD) 2011 Department of Respiratory Medicine, Osaka City University, Graduate School of Medicine, Osaka, Japan. pattypoti@hotmail.com
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Print(0)
Ref Type
Journal Article
Periodical, Full
Osaka city medical journal
Periodical, Abbrev.
Osaka City Med.J.
Pub Date Free Form
Jun
Volume
57
Issue
1
Start Page
21
Other Pages
29
Notes
JID: 0376413; ppublish
Place of Publication
Japan
ISSN/ISBN
0030-6096; 0030-6096
Accession Number
PMID: 22106764
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
22106764
Abstract
BACKGROUND: The six-minute walk test (6MWT) is widely used for integrated assessment of patients with chronic obstructive pulmonary disease (COPD). However, little is known concerning which resting pulmonary function test measurements relate to six-minute walk distance (6MWD). METHODS: We retrospectively analyzed consecutive data of spirometry, lung volume analysis, and measurements of diffusing capacity of the lung for carbon monoxide (DLCO) and 6MWT from total of one-hundred and thirty patients with COPD. Univariate and multivariate analyses were performed to examine the relationships between 6MWD and variables. RESULTS: By linear regression analysis, 6MWD was significantly associated with age, weight, BMI, FEV1.0, FEV1.0 (% predicted), IC, TLC, IC/TLC, FEF25-75, DLCO (% predicted), and DLCO/VA. Stepwise multiple regression analysis revealed that age (r2 = 0.173; p
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Database
Publisher
Data Source
Authors
Fujimoto,H., Asai,K., Watanabe,T., Kanazawa,H., Hirata,K.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Cigarette smoking and its association with overlapping gastroesophageal reflux disease, functional dyspepsia, or irritable bowel syndrome 2011 Department of Gastroenterology, Osaka City University Graduate School of Medicine, Japan. yasu@med.osaka-cu.ac.jp
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Print(0)
Ref Type
Journal Article
Periodical, Full
Internal medicine (Tokyo, Japan)
Periodical, Abbrev.
Intern.Med.
Pub Date Free Form
Volume
50
Issue
21
Start Page
2443
Other Pages
2447
Notes
LR: 20151119; JID: 9204241; 2011/11/01 [epublish]; ppublish
Place of Publication
Japan
ISSN/ISBN
1349-7235; 0918-2918
Accession Number
PMID: 22041340
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
JST.JSTAGE/internalmedicine/50.6012 [pii]
Output Language
Unknown(0)
PMID
22041340
Abstract
BACKGROUND: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD), and irritable bowel syndrome (IBS) are common gastrointestinal diseases. Several studies have shown a significant occurrence of overlap among these 3 diseases. The purpose of this study was to examine the factors associated with such disease overlap in Japanese adults. METHODS: We performed a cross-sectional study on Japanese workers who visited a clinic for a routine health check-up and asked them to fill out a self-report questionnaire. GERD was defined as episodes of heartburn and/or acid regurgitation at least once a week, and the diagnosis of FD and IBS was based on Rome III criteria. A logistic regression model was used to identify risk factors, and odds ratio (OR) was calculated with 95% confidence intervals (CIs). RESULTS: Disease overlaps were found in 160 (6.0%) of the 2680 eligible subjects. Female gender was associated with GERD + IBS (OR=1.99; 95% CI, 1.06-3.75), and FD + IBS (OR=1.72; 95% CI, 1.03-2.85), and lower body mass index was negatively associated with FD + IBS (OR=0.54; 96% CI, 0.34-0.87). Cigarette smoking was a common factor associated with the overlaps: GERD + FD (OR=2.14; 95% CI, 1.22-3.76), GERD + IBS (OR=3.16; 95% CI, 1.75-3.71), FD + IBS (OR=2.26; 95% CI, 1.40-3.66), and GERD + FD + IBS (OR=4.08; 95% CI, 1.66-10.07). The associations between smoking habits and overlaps were stronger in smokers who smoked >/=1 pack per day as compared to those who smoked
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Authors
Fujiwara,Y., Kubo,M., Kohata,Y., Machida,H., Okazaki,H., Yamagami,H., Tanigawa,T., Watanabe,K., Watanabe,T., Tominaga,K., Arakawa,T.
Original/Translated Title
URL
Date of Electronic
20111101
PMCID
Editors
Effects of dissuasive packaging on young adult smokers 2011 Department of Marketing, University of Otago, PO Box 56, Dunedin, 9054, New Zealand. janet.hoek@otago.ac.nz
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
May
Volume
20
Issue
3
Start Page
183
Other Pages
188
Notes
JID: 9209612; 2010/10/21 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 20966135
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1136/tc.2010.037861 [doi]
Output Language
Unknown(0)
PMID
20966135
Abstract
BACKGROUND: Tobacco industry documents illustrate how packaging promotes smoking experimentation and reinforces existing smokers' behaviour. Plain packaging reduces the perceived attractiveness of smoking and creates an opportunity to introduce larger pictorial warnings that could promote cessation-linked behaviours. However, little is known about the effects such a combined policy measure would have on smokers' behaviour. METHODS: A 3 (warning size) *4 (branding level) plus control (completely plain pack) best-worst experiment was conducted via face-to-face interviews with 292 young adult smokers from a New Zealand provincial city. The Juster Scale was also used to estimate cessation-linked behaviours among participants. RESULTS: Of the 13 options tested, respondents were significantly less likely to choose those featuring fewer branding elements or larger health warnings. Options that featured more branding elements were still preferred even when they also featured a 50% health warning, but were significantly less likely to be chosen when they featured a 75% warning. Comparison of a control pack representing the status quo (branded with 30% front of pack warning) and a plain pack (with a 75% warning) revealed the latter would be significantly more likely to elicit cessation-related behaviours. CONCLUSIONS: Plain packs that feature large graphic health warnings are significantly more likely to promote cessation among young adult smokers than fully or partially branded packs. The findings support the introduction of plain packaging and suggest use of unbranded package space to feature larger health warnings would further promote cessation.
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Database
Publisher
Data Source
Authors
Hoek,J., Wong,C., Gendall,P., Louviere,J., Cong,K.
Original/Translated Title
URL
Date of Electronic
20101021
PMCID
Editors
A novel graphene nanosheets coated stainless steel fiber for microwave assisted headspace solid phase microextraction of organochlorine pesticides in aqueous samples followed by gas chromatography with electron capture detection 2011 Department of Chemistry, National Chung-Hsing University, Taichung 402, Taiwan.
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Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
28-Sep
Volume
1218
Issue
39
Start Page
6861
Other Pages
6868
Notes
CI: Copyright (c) 2011; JID: 9318488; 0 (Hydrocarbons, Chlorinated); 0 (Pesticides); 0 (Water Pollutants, Chemical); 12597-68-1 (Stainless Steel); 7782-42-5 (Graphite); 2011/04/15 [received]; 2011/08/08 [revised]; 2011/08/08 [accepted]; 2011/08/16 [aheado
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 21872868
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.chroma.2011.08.019 [doi]
Output Language
Unknown(0)
PMID
21872868
Abstract
In this study, a novel graphene nanosheets (GNSs) coated solid phase microextraction (SPME) fiber was prepared by immobilizing microwave synthesized GNSs on a stainless steel wire. Microwave synthesized GNSs were verified by X-ray diffraction, field emission-scanning electron microscopy (FE-SEM) and transmission electron microscope (TEM). GNS-SPME fiber was characterized using FE-SEM and the results showed the GNS coating was homogeneous, porous, and highly adherent to the surface of the stainless steel fiber. The performance and feasibility of the GNS-SPME fiber was evaluated under one-step microwave assisted (MA) headspace (HS) SPME followed by gas chromatography with electron capture detection for five organochlorine pesticides (OCPs) in aqueous samples. Parameters influencing the extraction efficiency of MA-HS-GNS-SPME such as microwave irradiation power and time, pH, ionic strength, and desorption conditions were thoroughly examined. Under the optimized conditions, detection limits for the OCPs varied between 0.16 and 0.93 ng L(-1) and linear ranges varied between 1 and 1500 n gL(-1), with correlation coefficients ranging from 0.9984 to 0.9998, and RSDs in the range of 3.6-15.8% (n=5). In comparison with the commercial 100 mum polydimethylsiloxane fiber, the GNS coated fiber showed better extraction efficiency, higher mechanical and thermal stability (up to 290 degrees C), longer life span (over 250 times), and lower production cost. The method was successfully applied to the analysis of real water samples with recoveries ranged between 80.1 and 101.1% for river water samples. The results demonstrated that the developed MA-HS-GNS-SPME method was a simple, rapid, efficient pretreatment and environmentally friendly procedure for the analysis of OCPs in aqueous samples.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Ponnusamy,V.K., Jen,J.F.
Original/Translated Title
URL
Date of Electronic
20110816
PMCID
Editors
Measurement of fine particles and smoking activity in a statewide survey of 36 California Indian casinos 2011 Department of Civil and Environmental Engineering, Stanford University, Stanford, California 94305, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of exposure science & environmental epidemiology
Periodical, Abbrev.
J.Expo.Sci.Environ.Epidemiol.
Pub Date Free Form
Jan-Feb
Volume
21
Issue
1
Start Page
31
Other Pages
41
Notes
LR: 20141204; JID: 101262796; 0 (Air Pollutants); 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); OID: NLM: PMC3007589; 2010/02/17 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1559-064X; 1559-0631
Accession Number
PMID: 20160761
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1038/jes.2009.75 [doi]
Output Language
Unknown(0)
PMID
20160761
Abstract
Despite California's 1994 statewide smoking ban, exposure to secondhand smoke (SHS) continues in California's Indian casinos. Few data are available on exposure to airborne fine particles (PM(2).(5)) in casinos, especially on a statewide basis. We sought to measure PM(2).(5) concentrations in Indian casinos widely distributed across California, exploring differences due to casino size, separation of smoking and non-smoking areas, and area smoker density. A selection of 36 out of the 58 Indian casinos throughout California were each visited for 1-3 h on weekend or holiday evenings, using two or more concealed monitors to measure PM(2).(5) concentrations every 10 s. For each casino, the physical dimensions and the number of patrons and smokers were estimated. As a preliminary assessment of representativeness, we also measured eight casinos in Reno, NV. The average PM(2).(5) concentration for the smoking slot machine areas (63 mug/m(3)) was nine times as high as outdoors (7 mug/m(3)), whereas casino non-smoking restaurants (29 mug/m(3)) were four times as high. Levels in non-smoking slot machine areas varied: complete physical separation reduced concentrations almost to outdoor levels, but two other separation types had mean levels that were 13 and 29 mug/m(3), respectively, higher than outdoors. Elevated PM(2).(5) concentrations in casinos can be attributed primarily to SHS. Average PM(2).(5) concentrations during 0.5-1 h visits to smoking areas exceeded 35 mug/m(3) for 90% of the casino visits.
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Data Source
Authors
Jiang,R.T., Cheng,K.C., Acevedo-Bolton,V., Klepeis,N.E., Repace,J.L., Ott,W.R., Hildemann,L.M.
Original/Translated Title
URL
Date of Electronic
20100217
PMCID
PMC3007589
Editors
The SCIDOTS Project: evidence of benefits of an integrated tobacco cessation intervention in tuberculosis care on treatment outcomes 2011 Clinical Pharmacy and Practice Section, College of Pharmacy, Qatar University, P.O. Box 2713, Doha, Qatar. aawaisu@qu.edu.qa
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Substance abuse treatment, prevention, and policy
Periodical, Abbrev.
Subst.Abuse Treat.Prev.Policy.
Pub Date Free Form
23-Sep
Volume
6
Issue
Start Page
26
Other Pages
597X-6-26
Notes
LR: 20150129; JID: 101258060; OID: NLM: PMC3196696; 2011/05/26 [received]; 2011/09/23 [accepted]; 2011/09/23 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1747-597X; 1747-597X
Accession Number
PMID: 21943384
Language
eng
SubFile
Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1747-597X-6-26 [doi]
Output Language
Unknown(0)
PMID
21943384
Abstract
BACKGROUND: There is substantial evidence to support the association between tuberculosis (TB) and tobacco smoking and that the smoking-related immunological abnormalities in TB are reversible within six weeks of cessation. Therefore, connecting TB and tobacco cessation interventions may produce significant benefits and positively impact TB treatment outcomes. However, no study has extensively documented the evidence of benefits of such integration. SCIDOTS Project is a study from the context of a developing nation aimed to determine this. METHODS: An integrated TB-tobacco intervention was provided by trained TB directly observed therapy short-course (DOTS) providers at five chest clinics in Malaysia. The study was a prospective non-randomized controlled intervention using quasi-experimental design. Using Transtheoretical Model approach, 120 eligible participants who were current smokers at the time of TB diagnosis were assigned to either of two treatment groups: conventional TB DOTS plus smoking cessation intervention (integrated intervention or SCIDOTS group) or conventional TB DOTS alone (comparison or DOTS group). At baseline, newly diagnosed TB patients considering quitting smoking within the next 30 days were placed in the integrated intervention group, while those who were contemplating quitting were assigned to the comparison group. Eleven sessions of individualized cognitive behavioral therapy with or without nicotine replacement therapy were provided to each participant in the integrated intervention group. The impacts of the novel approach on biochemically validated smoking cessation and TB treatment outcomes were measured periodically as appropriate. RESULTS: A linear effect on both 7-day point prevalence abstinence and continuous abstinence was observed over time in the intervention group. At the end of 6 months, patients who received the integrated intervention had significantly higher rate of success in quitting smoking when compared with those who received the conventional TB treatment alone (77.5% vs. 8.7%; p
Descriptors
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Database
Publisher
Data Source
Authors
Awaisu,A., Nik Mohamed,M.H., Mohamad Noordin,N., Abd Aziz,N., Syed Sulaiman,S.A., Muttalif,A.R., Ahmad Mahayiddin,A.
Original/Translated Title
URL
Date of Electronic
20110923
PMCID
PMC3196696
Editors
Activities of triazole-echinocandin combinations against Candida species in biofilms and as planktonic cells 2011 3rd Department of Pediatrics, Aristotle University, Hippokration Hospital, Konstantinoupoleos 49, GR-54642 Thessaloniki, Greece.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
May
Volume
55
Issue
5
Start Page
1968
Other Pages
1974
Notes
LR: 20150204; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Pyrimidines); 0 (Triazoles); 6TK1G07BHZ (posaconazole); 9HLM53094I (anidulafungin); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole); OID: NLM: PMC3088240; 2011/02/22 [aheadofprin
Place of Publication
United States
ISSN/ISBN
1098-6596; 0066-4804
Accession Number
PMID: 21343465
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1128/AAC.00959-10 [doi]
Output Language
Unknown(0)
PMID
21343465
Abstract
Biofilm formation complicates the treatment of various infections caused by Candida species. We investigated the effects of simultaneous or sequential combinations of two triazoles, voriconazole (VRC) and posaconazole (PSC), with two echinocandins, anidulafungin (AND) and caspofungin (CAS), against Candida albicans and Candida parapsilosis biofilms in comparison to their planktonic counterparts. Antifungal activity was assessed by the 2,3-bis[2-methoxy-4-nitro-5-sulfophenyl]2H-tetrazolium-5-carboxanilide (XTT) metabolic assay. Antifungal-agent interactions were analyzed by the Bliss independence model in the simultaneous-treatment studies and by analysis of variance (ANOVA) in the sequential-treatment studies. Against C. albicans planktonic cells, the simultaneous combination of PSC (32 to 128 mg/liter) and CAS (0.008 to 0.25 mg/liter) was synergistic; the combinations of PSC (128 to 1,024 mg/liter) with AND (0.03 to 0.5 mg/liter) and VRC (32 to 512 mg/liter) with AND (0.008 to 0.03 mg/liter) were antagonistic. Against C. parapsilosis planktonic cells, the interaction between VRC (32 to 1,024 mg/liter) and CAS (1 to 16 mg/liter) was antagonistic. All simultaneous antifungal combinations demonstrated indifferent interactions against biofilms of both Candida species. Damage to biofilms of both species increased (P
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Database
Publisher
Data Source
Authors
Chatzimoschou,A., Katragkou,A., Simitsopoulou,M., Antachopoulos,C., Georgiadou,E., Walsh,T.J., Roilides,E.
Original/Translated Title
URL
Date of Electronic
20110222
PMCID
PMC3088240
Editors
One-year effects of vitamin D and calcium supplementation on chronic periodontitis 2011 Graduate Periodontics, Saint Louis University Center for Advanced Dental Education, St. Louis, MO 63104, USA. garciamn@slu.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of periodontology
Periodical, Abbrev.
J.Periodontol.
Pub Date Free Form
Jan
Volume
82
Issue
1
Start Page
25
Other Pages
32
Notes
LR: 20141205; GR: P30 AR057235/AR/NIAMS NIH HHS/United States; GR: R21 DE016918/DE/NIDCR NIH HHS/United States; GR: R21 DE016918/DE/NIDCR NIH HHS/United States; GR: UL1 RR024992/RR/NCRR NIH HHS/United States; GR: UL1 RR024992/RR/NCRR NIH HHS/United States
Place of Publication
United States
ISSN/ISBN
1943-3670; 0022-3492
Accession Number
PMID: 20809866
Language
eng
SubFile
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; D; IM
DOI
10.1902/jop.2010.100207 [doi]
Output Language
Unknown(0)
PMID
20809866
Abstract
BACKGROUND: A previous study reported by this group found that patients in periodontal maintenance programs taking vitamin D and calcium supplementation had a trend for better periodontal health compared to patients not taking supplementation. The objective of the present study is to determine, for the same cohort of subjects, whether such differences persist over a 1-year period. METHODS: Fifty-one patients enrolled in maintenance programs from two dental clinics were recruited. Of these, 23 were taking vitamin D (>/=400 IU/day) and calcium (>/=1,000 mg/day) supplementation, and 28 were not. All subjects had at least two interproximal sites with >/=3 mm clinical attachment loss. For mandibular-posterior teeth, gingival index, plaque index, probing depth, attachment loss, bleeding on probing, calculus index, and furcation involvement were evaluated. Photostimulable-phosphor, posterior bitewing radiographs were taken to assess alveolar bone. Daily vitamin D and calcium intakes were estimated by nutritional analysis. Data were collected at baseline, 6 months, and 12 months. RESULTS: Total daily calcium and vitamin D intakes were 1,769 mg (95% confidence interval, 1,606 to 1,933) and 1,049 IU (781 to 1,317) in the taker group, and 642 mg (505 to 779) and 156 IU (117 to 195) in the non-taker group, respectively (P
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Book Title
Database
Publisher
Data Source
Authors
Garcia,M.N., Hildebolt,C.F., Miley,D.D., Dixon,D.A., Couture,R.A., Spearie,C.L., Langenwalter,E.M., Shannon,W.D., Deych,E., Mueller,C., Civitelli,R.
Original/Translated Title
URL
Date of Electronic
20100901
PMCID
PMC3472001
Editors