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Title Sort ascending	Pub Year	Author	SearchLink
Parental smoking and children's respiratory health: independent effects of prenatal and postnatal exposure	2006	London School of Hygiene & Tropical Medicine, London, UK.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Aug Volume 15 Issue 4 Start Page 294 Other Pages 301 Notes LR: 20151119; JID: 9209612; 0 (Tobacco Smoke Pollution); RF: 40; OID: NLM: PMC2563598; ppublish Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 16885578 Language eng SubFile Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; IM DOI 15/4/294 [pii] Output Language Unknown(0) PMID 16885578 Abstract OBJECTIVES: Adverse effects have been reported of prenatal and/or postnatal passive exposure to smoking on children's health. Uncertainties remain about the relative importance of smoking at different periods in the child's life. We investigate this in a pooled analysis, on 53,879 children from 12 cross-sectional studies--components of the PATY study (Pollution And The Young). METHODS: Effects were estimated, within each study, of three exposures: mother smoked during pregnancy, parental smoking in the first two years, current parental smoking. Outcomes were: wheeze, asthma, "woken by wheeze", bronchitis, nocturnal cough, morning cough, "sensitivity to inhaled allergens" and hay fever. Logistic regressions were used, controlling for individual risk factors and study area. Heterogeneity between study-specific results, and mean effects (allowing for heterogeneity) were estimated using meta-analytical tools. RESULTS: There was strong evidence linking parental smoking to wheeze, asthma, bronchitis and nocturnal cough, with mean odds ratios all around 1.15, with independent effects of prenatal and postnatal exposures for most associations. CONCLUSIONS: Adverse effects of both pre- and postnatal parental smoking on children's respiratory health were confirmed. Asthma was most strongly associated with maternal smoking during pregnancy, but postnatal exposure showed independent associations with a range of other respiratory symptoms. All tobacco smoke exposure has serious consequences for children's respiratory health and needs to be reduced urgently. Descriptors Air Pollution, Indoor/adverse effects, Child, Child Welfare, Cough/etiology, Cross-Sectional Studies, Epidemiologic Methods, Female, Humans, Male, Parents, Pregnancy, Prenatal Exposure Delayed Effects, Prevalence, Respiratory Sounds/etiology, Respiratory Tract Diseases/epidemiology/etiology, Surveys and Questionnaires, Tobacco Smoke Pollution/adverse effects Links Book Title Database Publisher Data Source Authors Pattenden,S., Antova,T., Neuberger,M., Nikiforov,B., De Sario,M., Grize,L., Heinrich,J., Hruba,F., Janssen,N., Luttmann-Gibson,H., Privalova,L., Rudnai,P., Splichalova,A., Zlotkowska,R., Fletcher,T. Original/Translated Title URL Date of Electronic PMCID PMC2563598 Editors
Parental intentions to enroll children in a voluntary expanded newborn screening program	2016	Center for Communication Science, RTI International, Research Triangle Park, NC, United States. Electronic address: rpaquin@rti.org.; Center for P-12 Education, RTI International, Research Triangle Park, NC, United States.; Center for P-12 Education, RTI	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Social science & medicine (1982) Periodical, Abbrev. Soc.Sci.Med. Pub Date Free Form 29-Jul Volume 166 Issue Start Page 17 Other Pages 24 Notes LR: 20160815; CI: Copyright (c) 2016; JID: 8303205; OTO: NOTNLM; 2016/02/25 [received]; 2016/07/16 [revised]; 2016/07/26 [accepted]; aheadofprint Place of Publication ISSN/ISBN 1873-5347; 0277-9536 Accession Number PMID: 27526258 Language ENG SubFile JOURNAL ARTICLE DOI S0277-9536(16)30397-5 [pii] Output Language Unknown(0) PMID 27526258 Abstract BACKGROUND AND OBJECTIVES: Nearly all babies in the United States are tested at birth for rare, serious, and treatable disorders through mandatory state newborn screening (NBS). Recently, there have been calls for an expanded, voluntary model to facilitate early diagnosis and treatment of a wider range of disorders. We applied the reasoned action framework to examine parental intentions to participate in voluntary expanded screening. METHODS: We recruited a national cohort of recent and expectant parents living in the U.S. who completed a self-administered online survey (N = 1001). Using a mixed-level fractional factorial experiment, we studied parental participation intentions and preferences for timing of consent, cost, consent format, and testing options. RESULTS: We conducted a hierarchical regression analysis assessing parental intentions to participate in voluntary expanded NBS. Attitudes, perceived normative influence, and perceived behavioral control explained substantial variance in intention, with perceived normative influence emerging as the strongest predictor. We found no evidence that the manipulated program features altered mean levels of intention, but timing of parental permission, cost, and permission format moderated the relative importance of reasoned action constructs on intention. CONCLUSION: Program design features may impact the psychological mechanisms underlying parental decision making for voluntary expanded screening. These results have important implications for parent education, outreach, and informed parental permission procedures. Descriptors Links Book Title Database Publisher Elsevier Ltd Data Source Authors Paquin,R.S., Peay,H.L., Gehtland,L.M., Lewis,M.A., Bailey,D.B.,Jr Original/Translated Title URL Date of Electronic 20160729 PMCID Editors
Paradoxical growth effect of caspofungin observed on biofilms and planktonic cells of five different Candida species	2007	Division of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Antimicrobial Agents and Chemotherapy Periodical, Abbrev. Antimicrob.Agents Chemother. Pub Date Free Form Sep Volume 51 Issue 9 Start Page 3081 Other Pages 3088 Notes LR: 20140904; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Tetrazolium Salts); 117038-70-7 (2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazoliu m hydroxide); F0XDI6ZL63 (caspofungin); OID: NLM: PMC2043224; 2007/0 Place of Publication United States ISSN/ISBN 0066-4804; 0066-4804 Accession Number PMID: 17591847 Language eng SubFile Journal Article; IM DOI AAC.00676-07 [pii] Output Language Unknown(0) PMID 17591847 Abstract The paradoxical growth (PG) of Candida sp. biofilms in the presence of high caspofungin (CAS) concentrations was previously unknown. We sought to characterize the PG at supra-MICs of CAS among clinical Candida sp. isolates grown as biofilms in 96-well polystyrene microtiter plates. The MICs of CAS were determined for 30 clinical Candida sp. isolates (4 Candida albicans, 6 C. tropicalis, 7 C. parapsilosis, 8 C. orthopsilosis, and 5 C. metapsilosis isolates) when they were grown as planktonic cells and biofilms and were defined as the lowest drug concentrations that resulted in a prominent decrease in growth and a 50% reduction in metabolic activity, respectively. PG was defined as a resurgence of growth (>50% of that in the drug-free growth control well) at drug concentrations above the MIC. With the exception of C. tropicalis, all isolates displayed PG more frequently when they were grown as biofilms than when they grown as planktonic cells. PG was undetectable among C. metapsilosis isolates in planktonic cell MIC tests but was present in 100% of the isolates in biofilm MIC tests. The drug concentration and the number of drug dilutions supporting PG were higher for biofilms than for planktonic cells. Microscopic changes in cell morphology were observed among both planktonic and biofilm cells with PG. Specifically, the accumulation of enlarged, globose cells was associated with PG, and we hypothesize that CAS-induced changes in the cell wall composition may be the explanation. Descriptors Antifungal Agents/pharmacology, Biofilms/drug effects, Candida/drug effects/growth & development/physiology, Candidiasis/microbiology, Echinocandins/pharmacology, Microbial Sensitivity Tests, Risk, Tetrazolium Salts Links Book Title Database Publisher Data Source Authors Melo,A. S., Colombo,A. L., Arthington-Skaggs,B. A. Original/Translated Title URL Date of Electronic 20070625 PMCID PMC2043224 Editors
Paradoxical embolization and patent foramen ovale in scuba divers: screening possibilities	2007	Kardiovaskularni centrum FN Motol, Praha. tomas.honek@volny.cz	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Vnitrni lekarstvi Periodical, Abbrev. Vnitr.Lek. Pub Date Free Form Feb Volume 53 Issue 2 Start Page 143 Other Pages 146 Notes JID: 0413602; ppublish Place of Publication Czech Republic ISSN/ISBN 0042-773X; 0042-773X Accession Number PMID: 17419175 Language cze SubFile English Abstract; Journal Article; IM DOI Output Language Unknown(0) PMID 17419175 Abstract INTRODUCTION: The cause of decompression sickness (DCS) in scuba-divers is bubble formation in tissues and in venous blood during ascent. Divers with patent foramen ovale (PFO) have an increased risk of paradoxical embolization to the brain or other vital organs. The aim of our study was to assess the incidence of PFO in scuba-divers with DCS, to compare the group with asymptomatic controls, and to evaluate ultrasound contrast methods suitable for screening. METHODOLOGY: We examined 28 scuba-divers (more than 100 dives). The right-to-left shunt detection was performed by bubble contrast transthoracic echocardiographic examination (TTE) and transcranial Doppler sonography over arteria cerebri media (TCD) in all divers. In divers with shunting, transoesophageal echocardiography (TEE) was performed to prove PFO. RESULTS: 15 divers had DCS associated with the ascent. In this group, PFO was diagnosed in 53% (8/15). The symptoms of all of them retrospectively were of paradoxical embolization (neurological form of DCS). In the group of asymptomatic divers, PFO was proven on the basis of right-to-left shunt screening in 1 diver (8% 1/13). TCD proved right-to-left shunt in all divers with PFO. CONCLUSION: DCS can unmask a so far asymptomatic intracardiac right-to-left shunting. PFO is a risk factor for paradoxical embolization in divers. TCD is suitable for screening; TEE is a gold standard in PFO detection. Our results showed that PFO detection is a useful clinical tool after repeated DCS and in all frequent divers and instructors. Descriptors Adult, Decompression Sickness/etiology/prevention & control, Diving/adverse effects, Embolism, Paradoxical/etiology/prevention & control, Female, Heart Septal Defects, Atrial/complications/diagnosis, Humans, Male, Middle Aged Links Book Title Database Publisher Data Source Authors Honek,T., Veselka,J., Tomek,A., Sramek,M., Janugka,J., Sefc,L., Kerekes,R., Novotny,S. Original/Translated Title Paradoxni embolizace pri foramen ovale patens u potapecu: moznosti screeningu URL Date of Electronic PMCID Editors
Paradoxical antifungal activity and structural observations in biofilms formed by echinocandin-resistant Candida albicans clinical isolates	2014	University of New Mexico Health Science Center, Albuquerque.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Medical mycology Periodical, Abbrev. Med.Mycol. Pub Date Free Form Feb Volume 52 Issue 2 Start Page 131 Other Pages 139 Notes GR: T32 AI007538/AI/NIAID NIH HHS/United States; JID: 9815835; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Lipopeptides); 0 (Membrane Proteins); 0 (Mutant Proteins); 9HLM53094I (anidulafungin); EC 2.4.1.- (Glucosyltransferases); F0XDI6ZL63 (caspofungin); Place of Publication England ISSN/ISBN 1460-2709; 1369-3786 Accession Number PMID: 24576999 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; IM DOI 10.1093/mmy/myt007 [doi] Output Language Unknown(0) PMID 24576999 Abstract Echinocandin-resistant clinical isolates of Candida albicans have been reported, and key-hot spot mutations in the FKS1 gene, which encodes a major glucan synthase subunit, have been identified in these (caspofungin-resistant [CAS-R]) strains. Although these mutations result in phenotypic resistance to echinocandins in planktonic cells, there is little data on antifungal susceptibilities of CAS-R C. albicans strains within biofilms. Thus, we analyzed biofilms formed by 12 C. albicans CAS-R clinical strains in which we previously identified FKS1 hot-spot mutations and compared the sessile antifungal and paradoxical activity of anidulafungin (ANID), caspofungin (CAS), and micafungin (MICA). Biofilms were formed in a 96-well static microplate model and assayed using both tetrazolium-salt reduction and crystal violet assays, as well as examination by scanning electron microscopy. We first sought to assess biofilm formation and structure in these fks1 mutants and found that the biofilm mass and metabolic activities were reduced in most of the fks1 mutants as compared with reference strain SC5314. Structural analyses revealed that the fks1 mutant biofilms were generally less dense and had a clear predominance of yeast and pseudohyphae, with unusual "pit"-like cell surface structures. We also noted that sessile minimum inhibitory concentrations (MICs) to ANID, CAS, and MICA were higher than planktonic MICs of all but one strain. The majority of strains demonstrated a paradoxical effect (PE) to particular echinocandins, in either planktonic or sessile forms. Overall, biofilms formed by echinocandin-resistant clinical isolates demonstrated varied PEs to echinocandins and were structurally characterized by a preponderance of yeast, pseudohyphae, and pit-like structures. Descriptors Links Book Title Database Publisher Data Source Authors Walraven,C.J., Bernardo,S.M., Wiederhold,N.P., Lee,S.A. Original/Translated Title URL Date of Electronic 20131222 PMCID Editors
Paliperidonium nitrate	2012	School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 1-Oct Volume 68 Issue Pt 10 Start Page o2932 Other Pages Notes JID: 101089178; OID: NLM: PMC3470306; 2012/07/09 [received]; 2012/09/07 [accepted]; 2012/09/15 [epublish]; ppublish Place of Publication United States ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 23125719 Language eng SubFile Journal Article DOI 10.1107/S160053681203841X [doi] Output Language Unknown(0) PMID 23125719 Abstract In the title mol-ecular salt (systematic name: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]eth-yl}-9-hy-droxy-2-methyl- 1,6,7,8,9,9a-hexa-hydro-pyrido[1,2-a]pyrimidin-4-one nitrate), C(23)H(29)FN(4)O(3) (+).NO(3) (-), the piperidine ring displays a chair conformation and its N atom is protonated; the N-H bond is in an axial orientation. The ring bearing the hy-droxy group exhibits a half-chair conformation. The hy-droxy group as well as the adjacent methyl-ene group are disordered over two sets of sites in a 0.823 (5):0.177 (5) ratio. In the crystal, O-Hcdots, three dots, centeredN, O-Hcdots, three dots, centeredO, N-Hcdots, three dots, centeredO and N-Hcdots, three dots, centeredN hydrogen bonds connect the components into a three-dimensional network. Descriptors Links Book Title Database Publisher Data Source Authors Ge,J., Luo,Y.H. Original/Translated Title URL Date of Electronic 20120915 PMCID PMC3470306 Editors
Paan (pan) and paan (pan) masala should be considered tobacco products	2015	Division of General Internal Medicine, Department of Medicine, University of California, Davis, Sacramento, CA, USA Department of Health Sciences, California State University, East Bay, Hayward, CA, USA.; Institute for Population Health Improvement, Unive	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Tobacco control Periodical, Abbrev. Tob.Control Pub Date Free Form Dec Volume 24 Issue e4 Start Page e280 Other Pages 4 Notes CI: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/; GR: 1-TW-02-005/TW/FIC NIH HHS/United States; GR: U54CA15 Place of Publication England ISSN/ISBN 1468-3318; 0964-4563 Accession Number PMID: 25335900 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1136/tobaccocontrol-2014-051700 [doi] Output Language Unknown(0) PMID 25335900 Abstract Two products indigenous to the Indian subcontinent and popular among South Asians globally - paan and paan masala - are inconsistently categorised as tobacco by researchers, clinicians, program planners and policymakers. This article calls for a universally standard classification of these smokeless carcinogenic products as tobacco products and thus, subject to the same public health and clinical protections applied to other forms of tobacco. This recommendation is guided by scientific evidence strongly indicating the common presence of tobacco in paan and paan masala. Inclusion of these two products in population-level surveillance, clinical screening, as well as public health program planning and policy interventions may have considerable impact on preventing and reducing tobacco-related disparities among South Asians around the world. Descriptors Links Book Title Database Publisher Data Source Authors Mukherjea,A., Modayil,M.V., Tong,E.K. Original/Translated Title URL Date of Electronic 20141021 PMCID Editors
Ozone flux to Picea sitchensis (Bong) carr and Picea abies (L) karst during short episodes and the effects of these on transpiration and photosynthesis	1989	Forestry Commision, Forest Research Station, Farnham, GU10 4LH	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Environmental Pollution Periodical, Abbrev. Environ.Pollut. Pub Date Free Form 1989/ Volume 59 Issue 2 Start Page 161 Other Pages 176 Notes Place of Publication ISSN/ISBN 0269-7491 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Sitka spruce and Norway spruce were grown in controlled environments and then exposed to ozone (O3) for short periods as in mid-afternoon episodes experienced in the forest. For concentrations of between 20 and 300 nl litre-1 there were linear relationships between exposure concentration and O3 uptake rates. Increasing photon flux densities increased rates of photosynthesis and transpiration, the increases being larger in actively growing than dormant seedlings. Physiological condition (dormancy or active growth), species and photo flux density were found in influence O3 flux via their effects on stomatal conductance. Exposure to 80 nl litre-1 O3 resulted in consistent increases of stomatal conductance and there were also indications that water-use efficiency was decreased. Descriptors ozone, nonhuman, photosynthesis, plant, sweating Links Book Title Database Embase Publisher Data Source Embase Authors Freer-Smith,P. H., Dobson,M. C. Original/Translated Title URL Date of Electronic PMCID Editors
Oxidized multiwalled carbon nanotubes as a novel solid-phase microextraction fiber for determination of phenols in aqueous samples	2007	College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 21-Sep Volume 1165 Issue 2-Jan Start Page 10 Other Pages 17 Notes LR: 20131121; JID: 9318488; 0 (Nanotubes, Carbon); 0 (Phenols); 059QF0KO0R (Water); 2007/05/10 [received]; 2007/07/07 [revised]; 2007/07/10 [accepted]; 2007/07/31 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 0021-9673; 0021-9673 Accession Number PMID: 17707386 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI S0021-9673(07)01251-4 [pii] Output Language Unknown(0) PMID 17707386 Abstract A simple and environmentally friendly method for determination of seven phenols using solid-phase microextraction (SPME) coupled to high-performance liquid chromatography (HPLC) has been developed. Several materials were used as stationary phase of SPME fibers and an oxidized multiwalled carbon nanotubes material was found to be effective in carrying out simultaneous extraction of phenols in aqueous samples. Compared with the widely used commercially available SPME fibers, this proposed fiber had much lower cost, longer lifetime (over 150 times), shorter analysis time (30 min of extraction and 3 min of desorption time) and comparable or superior extraction efficiency for the investigated analytes. The extraction and desorption conditions were evaluated and the calibration curves of seven phenols were linear (R(2)> or =0.9908) in the range from 10.2 to 1585 ng mL(-1). The limits of detection at a signal-to-noise (S/N) ratio of 3 were 0.25-3.67 ng mL(-1), and the limits of quantification calculated at S/N=10 were 0.83-12.25 ng mL(-1) for these compounds. The possibility of applying the proposed method to environmental water samples analysis was validated. Descriptors Chromatography, High Pressure Liquid/methods, Nanotubes, Carbon/ultrastructure, Oxidation-Reduction, Phenols/isolation & purification, Reproducibility of Results, Solid Phase Microextraction/methods, Water/chemistry Links Book Title Database Publisher Data Source Authors Liu,X., Ji,Y., Zhang,Y., Zhang,H., Liu,M. Original/Translated Title URL Date of Electronic 20070731 PMCID Editors
Oxides of carbon, particulate matters and volatile organic compounds impact on indoor air quality during waterpipe smoking	2018		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International Journal of Environmental Science and Technology Periodical, Abbrev. Pub Date Free Form Volume Issue Start Page 1 Other Pages 6 Notes Place of Publication ISSN/ISBN Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors Links Book Title Database Publisher Springer Data Source google Authors Al-Dabbous, AN, Khan, AR, Al-Tamimi, SA, Shalash, M, Bajoga, AD, Malek, MJ Original/Translated Title URL Date of Electronic PMCID Editors

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