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WTS Database
The subject of interest is:
waterpipe, water-pipe, nargile, narghile, arguileh, arguile, shisha, sheesha, chichi, hubble bubble, hubbly bubbly, goza, hookah, bong
| Title | Pub Year | Author | SearchLink Sort ascending |
|---|---|---|---|
| Solvent-impregnated agarose gel liquid phase microextraction of polycyclic aromatic hydrocarbons in water | 2013 | Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia. | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of chromatography.A
Periodical, Abbrev.
J.Chromatogr.A
Pub Date Free Form
9-Aug
Volume
1302
Issue
Start Page
14
Other Pages
19
Notes
LR: 20131121; CI: Copyright (c) 2013; JID: 9318488; 0 (Polycyclic Hydrocarbons, Aromatic); 059QF0KO0R (Water); 9012-36-6 (Sepharose); OTO: NOTNLM; 2013/01/02 [received]; 2013/06/01 [revised]; 2013/06/03 [accepted]; 2013/06/14 [aheadofprint]; ppublish
Place of Publication
Netherlands
ISSN/ISBN
1873-3778; 0021-9673
Accession Number
PMID: 23809804
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.chroma.2013.06.010 [doi]
Output Language
Unknown(0)
PMID
23809804
Abstract
A new microextraction procedure termed agarose gel liquid phase microextraction (AG-LPME) combined with gas chromatography-mass spectrometry (GC-MS) was developed for the determination of selected polycyclic aromatic hydrocarbons (PAHs) in water. The technique utilized an agarose gel disc impregnated with the acceptor phase (1-octanol). The extraction procedure was performed by allowing the solvent-impregnated agarose gel disc to tumble freely in the stirred sample solution. After extraction, the agarose gel disc was removed and subjected to centrifugation to disrupt its framework and to release the impregnated solvent, which was subsequently withdrawn and injected into the GC-MS for analysis. Under optimized extraction conditions, the new method offered high enrichment factors (89-177), trace level LODs (9-14ngL(-1)) and efficient extraction with good relative recoveries in the range of 93.3-108.2% for spiked drinking water samples. AG-LPME did not exhibit any problems related to solvent dissolution, and it provided high extraction efficiencies that were comparable to those of hollow fiber liquid phase microextraction (HF-LPME) and significantly higher than those of agarose film liquid phase microextraction (AF-LPME). This technique employed a microextraction format and utilized an environmentally compatible solvent holder that supported the green chemistry concept.
Descriptors
Links
Book Title
Database
Publisher
Elsevier B.V
Data Source
Authors
Loh,S.H., Sanagi,M.M., Wan Ibrahim,W.A., Hasan,M.N.
Original/Translated Title
URL
Date of Electronic
20130614
PMCID
Editors
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| Controlled experiments measuring personal exposure to PM2.5 in close proximity to cigarette smoking | 2014 | Civil and Environmental Engineering Department, Stanford University, Stanford, CA, USA. | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Indoor air
Periodical, Abbrev.
Indoor Air
Pub Date Free Form
Apr
Volume
24
Issue
2
Start Page
199
Other Pages
212
Notes
CI: (c) 2013; JID: 9423515; 0 (Particulate Matter); 0 (Tobacco Smoke Pollution); OTO: NOTNLM; 2012/11/29 [received]; 2013/06/20 [accepted]; 2013/08/02 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1600-0668; 0905-6947
Accession Number
PMID: 23808850
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1111/ina.12057 [doi]
Output Language
Unknown(0)
PMID
23808850
Abstract
Few measurements of exposure to secondhand smoke (SHS) in close proximity to a smoker are available. Recent health studies have demonstrated an association between acute (160 mug/m(3) of PM2.5 . The average incremental exposure of the non-smokers was higher indoors (42 mug/m(3) , n = 35) than outdoors (29 mug/m(3) , n = 47), but the overall indoor and outdoor frequency distributions were similar. The 10-s PM2.5 averages during the smoking periods showed great variability, with multiple high concentrations of short duration (microplumes) both indoors and outdoors.
Descriptors
Links
Book Title
Database
Publisher
John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Data Source
Authors
Acevedo-Bolton,V., Ott,W.R., Cheng,K.C., Jiang,R.T., Klepeis,N.E., Hildemann,L.M.
Original/Translated Title
URL
Date of Electronic
20130802
PMCID
Editors
|
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| A qualitative exploration of young adult smokers' responses to novel tobacco warnings | 2013 | University of Otago, P O Box 56, Dunedin, New Zealand. janet.hoek@otago.ac.nz | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
25-Jun
Volume
13
Issue
Start Page
609
Other Pages
2458-13-609
Notes
LR: 20150423; JID: 100968562; OID: NLM: PMC3694466; 2013/02/01 [received]; 2013/06/18 [accepted]; 2013/06/25 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 23800292
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2458-13-609 [doi]
Output Language
Unknown(0)
PMID
23800292
Abstract
BACKGROUND: Despite reduced smoking among adolescents, smoking prevalence peaks among young adults aged 18-30, many of whom believe themselves exempt from the health risks of smoking shown in warning labels. We explored how young adult smokers perceived warnings featuring proximal risks, and whether these encouraged cessation more effectively than traditional health messages. METHODS: We conducted in-depth interviews with 17 young adult smokers and explored their perceptions of current warnings as well as novel warnings representing short-term health consequences; immediate social risks, and tobacco's toxicity (denormalizing tobacco as an everyday product). We used a thematic analysis approach to explore how participants rationalized existing warnings and interpreted the novel messages. RESULTS: Participants considered the immediate social and physiological benefits they gained from smoking outweighed the distal risks shown in health warnings, which they regarded as improbable and irrelevant. Of the novel warnings, those presenting immediate social risks altered the balance of gains and losses young adults associated with smoking; however, those presenting short-term health risks or depicting tobacco as a toxin were less effective. CONCLUSIONS: Participants regarded warnings featuring proximal social risks as more salient and they were less likely to rationalise these as irrelevant. Social risk messages merit further investigation to examine their potential as a complement to traditional health warnings.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Hoek,J., Hoek-Sims,A., Gendall,P.
Original/Translated Title
URL
Date of Electronic
20130625
PMCID
PMC3694466
Editors
|
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| Molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli in Tunisia and characterization of their virulence factors and plasmid addiction systems | 2013 | Laboratoire de Microbiologie, Hopital Habib Bourguiba, Sfax, Tunisie. basma_mnif@yahoo.fr | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC microbiology
Periodical, Abbrev.
BMC Microbiol.
Pub Date Free Form
25-Jun
Volume
13
Issue
Start Page
147
Other Pages
2180-13-147
Notes
LR: 20150423; JID: 100966981; 0 (Virulence Factors); EC 3.5.2.6 (beta-Lactamases); OID: NLM: PMC3701463; 2013/03/28 [received]; 2013/05/27 [accepted]; 2013/06/25 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-2180; 1471-2180
Accession Number
PMID: 23800277
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2180-13-147 [doi]
Output Language
Unknown(0)
PMID
23800277
Abstract
BACKGROUND: Extended-spectrum beta-lactamases (ESBLs), particularly CTX-M- type ESBLs, are among the most important resistance determinants spreading worldwide in Enterobacteriaceae. The aim of this study was to characterize a collection of 163 ESBL-producing Escherichia coli collected in Tunisia, their ESBL-encoding plasmids and plasmid associated addiction systems. RESULTS: The collection comprised 163 ESBL producers collected from two university hospitals of Sfax between 1989 and 2009. 118 isolates harbored blaCTX-M gene (101 blaCTX-M-15 gene and 17 blaCTX-M-14 gene). 49 isolates carried blaSHV-12 gene, 9 blaSHV-2a gene and only 3 blaTEM-26 gene. 16 isolates produced both CTX-M and SHV-12. The 101 CTX-M-15-producing isolates were significantly associated to phylogroup B2 and exhibiting a high number of virulence factors. 24 (23.7%) of the group B2 isolates belonged to clonal complex ST131. Pulsed-field gel electrophoresis (PFGE) typing revealed a genetic diversity of the isolates. 144 ESBL determinants were transferable mostly by conjugation. The majority of plasmid carrying blaCTX-M-15 genes (72/88) were assigned to various single replicon or multireplicon IncF types and had significantly a higher frequency of addiction systems, notably the VagCD module. CONCLUSION: This study demonstrates that the dissemination of CTX-M-15 producing E. coli in our setting was due to the spread of various IncF-type plasmids harboring multiple addiction systems, into related clones with high frequency of virulence determinants.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Mnif,B., Harhour,H., Jdidi,J., Mahjoubi,F., Genel,N., Arlet,G., Hammami,A.
Original/Translated Title
URL
Date of Electronic
20130625
PMCID
PMC3701463
Editors
|
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| 'Roll-your-own' cigarette smoking in South Africa between 2007 and 2010 | 2013 | Department of Community Dentistry, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa. lekan.ayoyusuf@up.ac.za. | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
24-Jun
Volume
13
Issue
Start Page
597
Other Pages
2458-13-597
Notes
LR: 20151119; JID: 100968562; OID: NLM: PMC3694453; 2013/01/02 [received]; 2013/06/14 [accepted]; 2013/06/24 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 23800007
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2458-13-597 [doi]
Output Language
Unknown(0)
PMID
23800007
Abstract
BACKGROUND: The prevalence of smoking and consumption of cigarettes have decreased in South Africa over the last 20 years. This decrease is a result of comprehensive tobacco control legislation, particularly large cigarette tax increases. However, little attention has been given to the potential use of 'roll-your-own' cigarettes as cheaper alternatives, especially among the socio-economically disadvantaged population. This study therefore sought to determine socio-demographic correlates of 'roll-your-own' cigarette use among South African adults (2007-2010). METHODS: This secondary data analysis used a merged dataset from two nationally representative samples of 2 907 and 3 112 South African adults (aged >/=16 years) who participated in the 2007 and 2010 annual South African Social Attitude Surveys respectively. The surveys used a face-to-face interviewer-administered questionnaire. The overall response rates were 83.1% for 2007 and 88.9% for 2010. Data elicited included socio-demographic data, current smoking status, type of tobacco products used, past quit attempts and self-efficacy in quitting. Data analysis included chi-square statistics and multi-variable adjusted logistic regression analysis. RESULTS: Of the 1 296 current smokers in this study, 24.1% (n = 306) reported using roll-your-own cigarettes. Some of whom also smoked factory-made cigarettes. Roll-your-own cigarette smoking was most common among black Africans and was more common among male smokers than among female smokers (27% vs 15.8%; p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Ayo-Yusuf,O.A., Olutola,B.G.
Original/Translated Title
URL
Date of Electronic
20130624
PMCID
PMC3694453
Editors
|
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| An epidemiologic analysis of low back pain in primary care: a hot humid country and global comparison | 2013 | Department of Medical Statistics & Epidemiology, Hamad Medical Corporation & Department of Public Health, Weill Cornell Medical College, Doha, Qatar. abener@hmc.org.qa | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of primary care & community health
Periodical, Abbrev.
J.Prim.Care.Community Health.
Pub Date Free Form
1-Jul
Volume
4
Issue
3
Start Page
220
Other Pages
227
Notes
LR: 20151119; JID: 101518419; OTO: NOTNLM; 2013/02/19 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
2150-1327; 2150-1319
Accession Number
PMID: 23799711
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1177/2150131913479385 [doi]
Output Language
Unknown(0)
PMID
23799711
Abstract
BACKGROUND: Low back pain is one of the most common conditions for which patients seek medical care. AIM: The aim of the study was to study the epidemiology of low back pain in primary care setting with emphasis on frequency, sociodemographic factors, and impact of low back pain on lifestyle habits. SUBJECTS AND METHODS: This is a cross-sectional study. A representative sample of 2742 patients was approached and 2180 subjects agreed to participate in this study (79.5%). The survey was conducted among primary health care visitors during the period from March to October 2012. The questionnaire collected the sociodemographic characteristics, lifestyle habits, and type of treatment taken for relief from recruited subjects. RESULTS: Of the subjects studied, 52.9% were males and 47.1% were females. The prevalence of low back pain in the study sample was 59.2%. Low back pain was more prevalent among women (67.7%) than among men (51.6%). The proportion of low back pain was highest in the age-group 45 to 55 years in both the genders (37.6% and 36.4%, respectively). Nearly half of the men (45.7%) and women (45.2%) with low back pain were overweight with a significant difference (P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Bener,A., Dafeeah,E.E., Alnaqbi,K., Falah,O., Aljuhaisi,T., Sadeeq,A., Khan,S., Schlogl,J.
Original/Translated Title
URL
Date of Electronic
20130219
PMCID
Editors
|
|||
| Neglected role of hookah and opium in gastric carcinogenesis: a cohort study on risk factors and attributable fractions | 2014 | Digestive Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of cancer
Periodical, Abbrev.
Int.J.Cancer
Pub Date Free Form
1-Jan
Volume
134
Issue
1
Start Page
181
Other Pages
188
Notes
LR: 20160303; CI: (c) 2013; JID: 0042124; 0 (Narcotics); 8008-60-4 (Opium); OTO: NOTNLM; 2013/04/12 [received]; 2013/05/30 [revised]; 2013/06/03 [accepted]; 2013/08/05 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1097-0215; 0020-7136
Accession Number
PMID: 23797606
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1002/ijc.28344 [doi]
Output Language
Unknown(0)
PMID
23797606
Abstract
A recent study showed an association between hookah/opium use and gastric cancer but no study has investigated the relationship with gastric precancerous lesions. We examined the association between hookah/opium and gastric precancerous lesions and subsequent gastric cancer. In a population-based cohort study, 928 randomly selected, healthy, Helicobacter pylori-infected subjects in Ardabil Province, Iran, were followed for 10 years. The association between baseline precancerous lesions and lifestyle risk factors (including hookah/opium) was analyzed using logistic regression and presented as odds ratios (ORs) and 95% confidence intervals (CIs). We also calculated hazard ratios (HRs) and 95% CIs for the associations of lifestyle risk factors and endoscopic and histological parameters with incident gastric cancers using Cox regression models. Additionally, the proportion of cancers attributable to modifiable risk factors was calculated. During 9,096 person-years of follow-up, 36 new cases of gastric cancer were observed (incidence rate: 3.96/1,000 persons-years). Opium consumption was strongly associated with baseline antral (OR: 3.2; 95% CI: 1.2-9.1) and body intestinal metaplasia (OR: 7.3; 95% CI: 2.5-21.5). Opium (HR: 3.2; 95% CI: 1.4-7.7), hookah (HR: 3.4; 95% CI: 1.7-7.1) and cigarette use (HR: 3.2; 95% CI: 1.4-7.5), as well as high salt intake, family history of gastric cancer, gastric ulcer and histological atrophic gastritis and intestinal metaplasia of body were associated with higher risk of gastric cancer. The fraction of cancers attributable jointly to high salt, low fruit intake, smoking (including hookah) and opium was 93% (95% CI: 83-98). Hookah and opium use are risk factors for gastric cancer as well as for precancerous lesions. Hookah, opium, cigarette and high salt intake are important modifiable risk factors in this high-incidence gastric cancer area.
Descriptors
Links
Book Title
Database
Publisher
UICC
Data Source
Authors
Sadjadi,A., Derakhshan,M.H., Yazdanbod,A., Boreiri,M., Parsaeian,M., Babaei,M., Alimohammadian,M., Samadi,F., Etemadi,A., Pourfarzi,F., Ahmadi,E., Delavari,A., Islami,F., Farzadfar,F., Sotoudeh,M., Nikmanesh,A., Alizadeh,B.Z., de Bock,G.H., Malekzadeh,R.
Original/Translated Title
URL
Date of Electronic
20130805
PMCID
Editors
|
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| Evaluation of electronic cigarette use (vaping) topography and estimation of liquid consumption: implications for research protocol standards definition and for public health authorities' regulation | 2013 | Onassis Cardiac Surgery Center, Sygrou 356, Kallithea, Greece. kfarsalinos@gmail.com | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of environmental research and public health
Periodical, Abbrev.
Int.J.Environ.Res.Public.Health.
Pub Date Free Form
18-Jun
Volume
10
Issue
6
Start Page
2500
Other Pages
2514
Notes
LR: 20151119; JID: 101238455; 6M3C89ZY6R (Nicotine); OID: NLM: PMC3717749; 2013/05/18 [received]; 2013/06/06 [revised]; 2013/06/07 [accepted]; epublish
Place of Publication
Switzerland
ISSN/ISBN
1660-4601; 1660-4601
Accession Number
PMID: 23778060
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; IM
DOI
10.3390/ijerph10062500 [doi]
Output Language
Unknown(0)
PMID
23778060
Abstract
BACKGROUND: Although millions of people are using electronic cigarettes (ECs) and research on this topic has intensified in recent years, the pattern of EC use has not been systematically studied. Additionally, no comparative measure of exposure and nicotine delivery between EC and tobacco cigarette or nicotine replacement therapy (NRTs) has been established. This is important, especially in the context of the proposal for a new Tobacco Product Directive issued by the European Commission. METHODS: A second generation EC device, consisting of a higher capacity battery and tank atomiser design compared to smaller cigarette-like batteries and cartomizers, and a 9 mg/mL nicotine-concentration liquid were used in this study. Eighty subjects were recruited; 45 experienced EC users and 35 smokers. EC users were video-recorded when using the device (ECIG group), while smokers were recorded when smoking (SM-S group) and when using the EC (SM-E group) in a randomized cross-over design. Puff, inhalation and exhalation duration were measured. Additionally, the amount of EC liquid consumed by experienced EC users was measured at 5 min (similar to the time needed to smoke one tobacco cigarette) and at 20 min (similar to the time needed for a nicotine inhaler to deliver 4 mg nicotine). RESULTS: Puff duration was significantly higher in ECIG (4.2 +/- 0.7 s) compared to SM-S (2.1 +/- 0.4 s) and SM-E (2.3 +/- 0.5 s), while inhalation time was lower (1.3 +/- 0.4, 2.1 +/- 0.4 and 2.1 +/- 0.4 respectively). No difference was observed in exhalation duration. EC users took 13 puffs and consumed 62 +/- 16 mg liquid in 5 min; they took 43 puffs and consumed 219 +/- 56 mg liquid in 20 min. Nicotine delivery was estimated at 0.46 +/- 0.12 mg after 5 min and 1.63 +/- 0.41 mg after 20 min of use. Therefore, 20.8 mg/mL and 23.8 mg/mL nicotine-containing liquids would deliver 1 mg of nicotine in 5 min and 4 mg nicotine in 20 min, respectively. Since the ISO method significantly underestimates nicotine delivery by tobacco cigarettes, it seems that liquids with even higher than 24 mg/mL nicotine concentration would be comparable to one tobacco cigarette. CONCLUSIONS: EC use topography is significantly different compared to smoking. Four-second puffs with 20-30 s interpuff interval should be used when assessing EC effects in laboratory experiments, provided that the equipment used does not get overheated. Based on the characteristics of the device used in this study, a 20 mg/mL nicotine concentration liquid would be needed in order to deliver nicotine at amounts similar to the maximum allowable content of one tobacco cigarette (as measured by the ISO 3308 method). The results of this study do not support the statement of the European Commission Tobacco Product Directive that liquids with nicotine concentration of 4 mg/mL are comparable to NRTs in the amount of nicotine delivered to the user.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Farsalinos,K.E., Romagna,G., Tsiapras,D., Kyrzopoulos,S., Voudris,V.
Original/Translated Title
URL
Date of Electronic
20130618
PMCID
PMC3717749
Editors
|
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| Khat chewing habit among school students of Jazan region, Saudi Arabia | 2013 | Family and Community Medicine Department, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia. | Read more... |
|
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
PloS one
Periodical, Abbrev.
PLoS One
Pub Date Free Form
11-Jun
Volume
8
Issue
6
Start Page
e65504
Other Pages
Notes
LR: 20151119; JID: 101285081; OID: NLM: PMC3679146; 2013 [ppublish]; 2013/02/12 [received]; 2013/04/26 [accepted]; 2013/06/11 [epublish]; epublish
Place of Publication
United States
ISSN/ISBN
1932-6203; 1932-6203
Accession Number
PMID: 23776490
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1371/journal.pone.0065504 [doi]
Output Language
Unknown(0)
PMID
23776490
Abstract
BACKGROUND: The use of Khat leaves (Catha edulis) in Jazan, southwest of KSA, is prevalent among all segments of the population. OBJECTIVE: This study was conducted to assess the prevalence and predictors of Khat chewing among intermediate and secondary school students of Jazan region. METHODOLOGY: A cross-sectional survey was conducted in late 2011 in Jazan region. A random sample of 3923 students was selected from 72 intermediate and upper secondary schools representing the different educational sectors of the region. A structured self-administered questionnaire was used for data collection. Descriptive statistics, a chi-squared test and logistic regression were performed to examine the prevalence, associations and predictors of Khat chewing. RESULT: The overall Khat chewing prevalence among students was 20.5% (95% C.I.: 19.27-21.79). The prevalence was significantly higher among males, at 33.1% (95% CI: 31.16-35.08), than among females 4.3% (95% C.I.: 3.39-5.31) ( P
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Alsanosy,R.M., Mahfouz,M.S., Gaffar,A.M.
Original/Translated Title
URL
Date of Electronic
20130611
PMCID
PMC3679146
Editors
|
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| Clinical features of patients with infections caused by Candida guilliermondii and Candida fermentati and antifungal susceptibility of the isolates at a medical centre in Taiwan, 2001-10 | 2013 | Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. | Read more... |
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Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of antimicrobial chemotherapy
Periodical, Abbrev.
J.Antimicrob.Chemother.
Pub Date Free Form
Nov
Volume
68
Issue
11
Start Page
2632
Other Pages
2635
Notes
JID: 7513617; 0 (Antifungal Agents); OTO: NOTNLM; 2013/06/13 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1460-2091; 0305-7453
Accession Number
PMID: 23766486
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1093/jac/dkt214 [doi]
Output Language
Unknown(0)
PMID
23766486
Abstract
OBJECTIVES: This study was intended to analyse the clinical characteristics and outcomes of patients with infections due to Candida guilliermondii complex and evaluate in vitro susceptibilities of the isolates. METHODS: We searched the Mycology Database of the National Taiwan University Hospital and identified patients with infections due to C. guilliermondii complex from 2001 to 2010. Isolates were identified to species level by two yeast identification systems and restriction fragment length polymorphism of the riboflavin synthetase gene. MICs of nine antifungal agents were determined using the Sensititre YeastOne system (Trek Diagnostic Systems) and were interpreted by breakpoints (BPs) for three echinocandins and epidemiological cut-off values (ECVs) for the other agents. RESULTS: Fifty-two patients with infections due to C. guilliermondii complex were evaluated. The majority (90%, n = 47) of the isolates were C. guilliermondii, followed by Candida fermentati (10%, n = 5). Among them, 42 (81%) were isolated from blood cultures. Among the 52 patients, 27 (52%) had underlying malignancy and 15 (29%) had undergone abdominal surgery. The 30 day mortality rates among patients with C. guilliermondii and C. fermentati infections were 45% and 60%, respectively. Among C. guilliermondii isolates, 98%, 100% and 98% were susceptible to caspofungin, micafungin and anidulafungin, respectively, by BPs. Nearly all (96%-100%) C. guilliermondii isolates belonged to wild-type for the other agents by ECVs. All five C. fermentati were susceptible to three echinocandins and belonged to wild-type for the other agents. CONCLUSIONS: The currently used antifungal agents exhibited good in vitro activities against C. guilliermondii complex isolates.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Chen,C.Y., Huang,S.Y., Tang,J.L., Tsay,W., Yao,M., Ko,B.S., Chou,W.C., Tien,H.F., Hsueh,P.R.
Original/Translated Title
URL
Date of Electronic
20130613
PMCID
Editors
|
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