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Patent foramen ovale: an underrated risk for divers? 2004 Klinik fur Anasthesiologie und Spezielle Intensivmedizin, Rheinische Friedrich-Wilhelms-Universitat Bonn. Heiko.Lier@ukb.uni-bonn.de
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Deutsche medizinische Wochenschrift (1946)
Periodical, Abbrev.
Dtsch.Med.Wochenschr.
Pub Date Free Form
2-Jan
Volume
129
Issue
2-Jan
Start Page
27
Other Pages
30
Notes
LR: 20061115; JID: 0006723; RF: 26; ppublish
Place of Publication
Germany
ISSN/ISBN
0012-0472; 0012-0472
Accession Number
PMID: 14703578
Language
ger
SubFile
English Abstract; Journal Article; Review; IM
DOI
10.1055/s-2004-812652 [doi]
Output Language
Unknown(0)
PMID
14703578
Abstract
The foramen ovale which is the fetal connection between the right and left atrium persists in about 30 % of the adult population. In the presence of a persistent foramen ovale (PFO) shunting of blood may occur from the right to the left atrium, and bubbles can reach the systemic circulation during or after the decompression phase of a dive with compressed air. Therefore, divers with PFO may have an increased risk to develop ischemic cerebral lesions and neurologic decompression sickness (DCS). Significant right-to-left shunting may be diagnosed using transcranial doppler ultrasound of the medial cerebral artery and echocardiography with echo contrast media and Valsalva provocation. However, there are no official guidelines concerning PFO screening in medical fitness exams for professional or recreational divers in Germany. Therefore, it remains in the diver's choice to be screened for PFO. Divers with a history of DCS should be monitored for PFO, especially when diving strictly adhered to decompression tables. Divers with PFO who refuse to stop diving after DCS should be advised to adhere to very save dive profiles.
Descriptors
Decompression Sickness/etiology, Diving, Echocardiography, Doppler, Echocardiography, Transesophageal, Heart Septal Defects, Atrial/complications/diagnosis/physiopathology, Humans, Mass Screening, Risk Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Lier,H., Schroeder,S., Hering,R.
Original/Translated Title
Persistierendes Foramen ovale: ein unterschatztes Risiko fur Taucher?
URL
Date of Electronic
PMCID
Editors
Patent foramen ovale: a review of associated conditions and the impact of physiological size 2001 Cardiovascular Research Laboratory, Division of Cardiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112-2822, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of the American College of Cardiology
Periodical, Abbrev.
J.Am.Coll.Cardiol.
Pub Date Free Form
Sep
Volume
38
Issue
3
Start Page
613
Other Pages
623
Notes
LR: 20071115; JID: 8301365; RF: 66; ppublish
Place of Publication
United States
ISSN/ISBN
0735-1097; 0735-1097
Accession Number
PMID: 11527606
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Review; AIM; IM; S
DOI
S0735-1097(01)01427-9 [pii]
Output Language
Unknown(0)
PMID
11527606
Abstract
Patent foramen ovale (PFO) is implicated in platypnea-orthodeoxia, stroke and decompression sickness (DCS) in divers and astronauts. However, PFO size in relation to clinical illness is largely unknown since few studies evaluate PFO, either functionally or anatomically. The autopsy incidence of PFO is approximately 27% and 6% for a large defect (0.6 cm to 1.0 cm). A PFO is often associated with atrial septal aneurysm and Chiari network, although these anatomic variations are uncommon. Methodologies for diagnosis and anatomic and functional sizing of a PFO include transthoracic echocardiography (TTE), transesophageal echocardiography (TEE) and transcranial Doppler (TCD), with saline contrast. Saline injection via the right femoral vein appears to have a higher diagnostic yield for PFO than via the right antecubital vein. Saline contrast with TTE using native tissue harmonics or transmitral pulsed wave Doppler have quantitated PFO functional size, while TEE is presently the reference standard. The platypnea-orthodeoxia syndrome is associated with a large resting PFO shunt. Transthoracic echocardiography, TEE and TCD have been used in an attempt to quantitate PFO in patients with cryptogenic stroke. The larger PFOs (approximately > or =4 mm size) or those with significant resting shunts appear to be clinically significant. Approximately two-thirds of divers with unexplained DCS have a PFO that may be responsible and may be related to PFO size. Limited data are available on the incidence of PFO in high altitude aviators with DCS, but there appears to be a relationship. A large decompression stress is associated with extra vehicular activity (EVA) from spacecraft. After four cases of serious DCS in EVA simulations, a resting PFO was detected by contrast TTE in three cases. Patent foramen ovales vary in both anatomical and functional size, and the clinical impact of a particular PFO in various situations (platypnea-orthodeoxia, thromboembolism, DCS in underwater divers, DCS in high-altitude aviators and astronauts) may be different.
Descriptors
Aerospace Medicine, Coronary Circulation, Decompression Sickness/complications/ultrasonography, Diving, Echocardiography, Transesophageal, Embolism, Paradoxical/etiology, Heart Septal Defects, Atrial/diagnosis/pathology/physiopathology, Heart Septum/embryology, Humans, Stroke/etiology, Ultrasonography, Doppler, Transcranial
Links
Book Title
Database
Publisher
Data Source
Authors
Kerut,E. K., Norfleet,W. T., Plotnick,G. D., Giles,T. D.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Patent foramen ovale influences the presentation of decompression illness in SCUBA divers 2015 Eastern Heart Clinic, Prince of Wales Hospital, Barker Street, Randwick, 2031, Australia. Electronic address: k_liou@hotmail.com.; Australian Diving and Hyperbaric Medicine Research Group, Prince of Wales Hospital, Barker Street, Randwick, 2031, Australia
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Heart, lung & circulation
Periodical, Abbrev.
Heart Lung Circ.
Pub Date Free Form
Jan
Volume
24
Issue
1
Start Page
26
Other Pages
31
Notes
CI: Copyright (c) 2014; JID: 100963739; OTO: NOTNLM; 2014/04/22 [received]; 2014/07/02 [revised]; 2014/07/07 [accepted]; 2014/07/17 [aheadofprint]; ppublish
Place of Publication
Australia
ISSN/ISBN
1444-2892; 1443-9506
Accession Number
PMID: 25130890
Language
eng
SubFile
Journal Article; IM
DOI
10.1016/j.hlc.2014.07.057 [doi]
Output Language
Unknown(0)
PMID
25130890
Abstract
BACKGROUND: Few have examined the influence of patent foramen ovale (PFO) on the phenotype of decompression illness (DCI) in affected divers. METHODOLOGY: A retrospective review of our database was performed for 75 SCUBA divers over a 10-year period. RESULTS: Overall 4,945 bubble studies were performed at our institution during the study period. Divers with DCI were more likely to have positive bubble studies than other indications (p
Descriptors
Links
Book Title
Database
Publisher
Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V
Data Source
Authors
Liou,K., Wolfers,D., Turner,R., Bennett,M., Allan,R., Jepson,N., Cranney,G.
Original/Translated Title
URL
Date of Electronic
20140717
PMCID
Editors
Patent Foramen Ovale in Recreational and Professional Divers: An Important and Largely Unrecognized Problem 2015 Department of Cardiology, Charles University in Prague, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic; Institute of Pathological Physiology, Charles University in Prague, 1st Faculty of Medicine, Prague, Czech Republic.; In
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Canadian journal of cardiology
Periodical, Abbrev.
Can.J.Cardiol.
Pub Date Free Form
Aug
Volume
31
Issue
8
Start Page
1061
Other Pages
1066
Notes
CI: Copyright (c) 2015; JID: 8510280; 2015/01/25 [received]; 2015/03/10 [revised]; 2015/03/10 [accepted]; 2015/03/12 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1916-7075; 0828-282X
Accession Number
PMID: 26143138
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Review; IM
DOI
10.1016/j.cjca.2015.03.010 [doi]
Output Language
Unknown(0)
PMID
26143138
Abstract
Patent foramen ovale (PFO) is associated with an increased risk of decompression sickness (DCS) in divers that results from a paradoxical embolization of nitrogen bubbles. The number of scuba divers worldwide is estimated in the millions, and the prevalence of PFO is 25%-30% in adults. It is interesting that despite these numbers, many important issues regarding optimal screening, risk stratification, and management strategy still remain to be resolved. Recently published data suggest the possible effectiveness of both PFO closure and conservative diving measures in preventing arterial gas embolization. This review aims to introduce the basic principles of physiology and the pathophysiology of bubble formation and DCS, summarize the current literature on PFO and diving, and review the possibilities of diagnostic workup and management.
Descriptors
Links
Book Title
Database
Publisher
Canadian Cardiovascular Society. Published by Elsevier Inc
Data Source
Authors
Honek,J., Sefc,L., Honek,T., Sramek,M., Horvath,M., Veselka,J.
Original/Translated Title
URL
Date of Electronic
20150312
PMCID
Editors
Patent foramen ovale closure in recreational divers: effect on decompression illness and ischaemic brain lesions during long-term follow-up 2011 Department of Cardiology, University Hospital, Bern, Switzerland.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Heart (British Cardiac Society)
Periodical, Abbrev.
Heart
Pub Date Free Form
Dec
Volume
97
Issue
23
Start Page
1932
Other Pages
1937
Notes
LR: 20140730; JID: 9602087; 2011/09/13 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1468-201X; 1355-6037
Accession Number
PMID: 21917666
Language
eng
SubFile
Journal Article; AIM; IM
DOI
10.1136/heartjnl-2011-300436 [doi]
Output Language
Unknown(0)
PMID
21917666
Abstract
OBJECTIVE: To test the effect of patent foramen ovale (PFO) closure on neurological events in divers. DESIGN: Prospective, non-randomised, longitudinal three-arm study. SETTING: Tertiary referral centre. POPULATION: 104 scuba divers with a history of major decompression illness (DCI). INTERVENTION: Transcutaneous PFO closure. MAIN OUTCOME MEASURES: Baseline and three follow-up examinations with a questionnaire about health status and diving habits/accidents, transoesophageal echocardiography at baseline for PFO grading, cerebral MRI at all examinations. RESULTS: 39 divers had no PFO, 26 had a PFO and chose to undergo percutaneous closure and 39 had a PFO, but decided not to undergo closure. The total number of dives, including those performed before baseline and those during long-term follow-up, was 81,654; 18,394 dives during the follow-up period of 5.3 +/- 0.3 years, during which there were a total of five major neurological DCI events-namely 0 in the no PFO group, 0.5 +/- 2.5/10(4) dives in the PFO closure group and 35.8 +/- 102.5/10(4) dives in the PFO no closure group (four events; p = 0.045 between the PFO groups). In the groups, no PFO, PFO closure and PFO no closure, there were 1.1 +/- 2.6, 0.8 +/- 1.4, 3.3 +/- 6.9 ischaemic brain lesions, respectively, at follow-up (p = 0.039 between the PFO groups)-that is, 16 +/- 42/10(4) dives in the no PFO group, 6 +/- 13/10(4) dives in the PFO closure group and 104 +/- 246/10(4) dives in the PFO no closure group (overall p = 0.042; p = 0.024 between the PFO groups). CONCLUSION: PFO closure in continuing divers appears to prevent symptomatic (major DCI) and asymptomatic (ischaemic brain lesions) neurological events during long-term follow-up.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Billinger,M., Zbinden,R., Mordasini,R., Windecker,S., Schwerzmann,M., Meier,B., Seiler,C.
Original/Translated Title
URL
Date of Electronic
20110913
PMCID
Editors
Patent foramen ovale and the risk of paradoxical embolization of venous bubbles in divers - cave for foam sclerotization of varicose veins 2012 Kardiologicka klinika. jakub.honek@gmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti
Periodical, Abbrev.
Rozhl.Chir.
Pub Date Free Form
Jul
Volume
91
Issue
7
Start Page
378
Other Pages
380
Notes
JID: 9815441; ppublish
Place of Publication
Czech Republic
ISSN/ISBN
0035-9351; 0035-9351
Accession Number
PMID: 23078256
Language
cze
SubFile
English Abstract; Journal Article; IM
DOI
38891 [pii]
Output Language
Unknown(0)
PMID
23078256
Abstract
INTRODUCTION: Foam sclerotization of varicose veins may cause paradoxical embolization through patent foramen ovale (PFO). The aim of our study was to: 1) select an optimal screening method for the detection of PFO; 2) determine the prevalence of PFO in a non-selected population; and 3) test the risk of paradoxical embolization of venous bubbles in patients with PFO. MATERIALS AND METHODS: A diver after decompression is a suitable model for determining the risk of paradoxical embolization of venous gas bubbles. 329 Czech divers were screened for PFO. In a pilot study, we compared Transcranial Doppler Sonography (TCD) with Transesophageal Echocardiography (TEE) in 100 patients. TCD alone was used for further screening. In 31 divers with PFO, nitrogen bubbles were detected after simulated dives. Transthoracic Echocardiography (TTE) was used to detect venous bubbles in right-sided heart chambers; TTE and TCD were used to detect arterial bubbles. The right-to-left shunt was rated as non-significant (
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Honek,J., Honek,T., Januska,J., Sebesta,P., Novotny,S., Sefc,L., Fiedler,J., Sramek,M., Horvath,M., Parobkova,M.
Original/Translated Title
Perzistence foramen ovale patens a riziko paradoxni embolizace zilnich bublin u potapecu - cave pro sklerotizaci varixu penovou metodou
URL
Date of Electronic
PMCID
Editors
Patent foramen ovale and diving 2005 Centre for Hyperbaric Oxygen Therapy, Military Hospital Brussels, Bruynstraat 200, Brussels 1120, Belgium. peter.germonpre@mil.be
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Cardiology clinics
Periodical, Abbrev.
Cardiol.Clin.
Pub Date Free Form
Feb
Volume
23
Issue
1
Start Page
97
Other Pages
104
Notes
LR: 20091103; JID: 8300331; RF: 60; ppublish
Place of Publication
United States
ISSN/ISBN
0733-8651; 0733-8651
Accession Number
PMID: 15676273
Language
eng
SubFile
Journal Article; Review; IM
DOI
S0733-8651(04)00082-7 [pii]
Output Language
Unknown(0)
PMID
15676273
Abstract
Patency of the foramen ovale is a risk factor for DCS in SCUBA divers, even if they adhere to the currently accepted and used decompression tables. The primary cause of DCS, however, is the nitrogen bubble, not the PFO. There are a number of techniques any diver can use to minimize the occurrence of nitrogen bubbles after a dive. The authors current practice is to inform civilian sports divers of the increased risk and to advise them to adopt conservative dive profiles. This can be achieved by selecting a more conservative dive computer, performing only dives that do not require obligatory decompression stops, or using oxygen-enriched breathing gas mixtures("nitrox") while still diving on "air profiles" [56].Dive-safety organizations are currently under-taking studies aimed at proposing changes in the decompression algorithms to produce low-bubble dive tables [12]. In the meantime, PFO remains a reason for caution. Whether all divers should be screened for PFOis an ongoing discussion [50] in view of methodologic and practical issues outlined in this article. Any definitive recommendations can be made only after a careful, prospective evaluation of the real relative risk for DCS and long-term cerebral damage.
Descriptors
Decompression Sickness/epidemiology/physiopathology, Diving/adverse effects, Embolism/etiology/physiopathology, Heart Septal Defects, Atrial/epidemiology/physiopathology, Humans, Risk Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Germonpre,P.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Patent foramen ovale and decompression sickness in divers 1989 Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Lancet (London, England)
Periodical, Abbrev.
Lancet
Pub Date Free Form
11-Mar
Volume
1
Issue
8637
Start Page
513
Other Pages
514
Notes
LR: 20150616; JID: 2985213R; CIN: Lancet. 1990 Sep 1;336(8714):568. PMID: 1975062; ppublish
Place of Publication
ENGLAND
ISSN/ISBN
0140-6736; 0140-6736
Accession Number
PMID: 2564057
Language
eng
SubFile
Comparative Study; Journal Article; AIM; IM
DOI
Output Language
Unknown(0)
PMID
2564057
Abstract
30 patients with a history of decompression sickness were examined for the presence of patent foramen ovale by bubble contrast, two-dimensional echocardiography and colour flow doppler imaging. With bubble contrast, 11 (37%) of the patients had right-to-left shunting through a patent foramen ovale during spontaneous breathing. 61% of a subset of 18 patients with serious signs and symptoms had shunting. This number was significantly higher than the 5% prevalence seen with the same diagnostic technique in 176 healthy volunteers. The presence of patent foramen ovale seems to be a risk factor for the development of decompression sickness in divers.
Descriptors
Acute Disease, Adolescent, Adult, Child, Decompression Sickness/etiology, Diving/adverse effects, Echocardiography, Echocardiography, Doppler, Female, Heart Septal Defects, Atrial/complications/diagnosis/physiopathology, Humans, Male, Middle Aged, Valsalva Maneuver
Links
Book Title
Database
Publisher
Data Source
Authors
Moon,R. E., Camporesi,E. M., Kisslo,J. A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Patent foramen ovale and decompression illness in divers 2010 Seksjon for pediatri, Institutt for klinisk medisin, Universitetet i Bergen, Norway.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
Periodical, Abbrev.
Tidsskr.Nor.Laegeforen.
Pub Date Free Form
22-Apr
Volume
130
Issue
8
Start Page
834
Other Pages
838
Notes
JID: 0413423; RF: 41; ppublish
Place of Publication
Norway
ISSN/ISBN
0807-7096; 0029-2001
Accession Number
PMID: 20418929
Language
nor
SubFile
English Abstract; Journal Article; Review; IM
DOI
10.4045/tidsskr.09.0377 [doi]
Output Language
Unknown(0)
PMID
20418929
Abstract
BACKGROUND: About 25 % of the population has patent foramen ovale, and the condition has been assumed to be a causal factor in decompressive illness. Transcatheter closure is possible and is associated with a relatively low risk, but it has not been clarified whether there is an indication for assessment and treatment of the condition in divers. The present study explored a possible relationship between a patent foramen ovale and the risk for decompression illness in divers, if there are categories of divers that should be screened for the condition and what advice should be given to divers with this condition. MATERIAL AND METHODS: The review is based on literature identified through a search in Pubmed and the authors' long clinical experience in the field. RESULTS: The risk of decompression illness for divers with a persistent foramen ovale is about five times higher than that in divers without this condition, but the absolute risk for decompression illness is only 2.5 after 10,000 dives. A causal association has not been shown between patent foramen ovale and decompression illness. Even if closure of patent foramen ovale may be done with relatively small risk, the usefulness of the procedure has not been documented in divers. INTERPRETATION: We do not recommend screening for patent foramen ovale in divers because the absolute risk of decompression illness is small and transcatheter closure is only indicated after decompression illness in some occupational divers.
Descriptors
Decompression Sickness/etiology, Diving/injuries, Echocardiography, Transesophageal, Foramen Ovale, Patent/complications/diagnosis/therapy, Humans, Occupational Health, Risk Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Sivertsen,W., Risberg,J., Norgard,G.
Original/Translated Title
Apent foramen ovale og trykkfallssyke hos dykkere
URL
Date of Electronic
PMCID
Editors
Passive versus active parental permission: implications for the ability of school-based depression screening to reach youth at risk 2008 Psychology, PGSP-Stanford Consortium, 247 San Carlos Ave, Redwood City, CA 94061, USA. mpcpsyd@stanford.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of school health
Periodical, Abbrev.
J.Sch.Health
Pub Date Free Form
Mar
Volume
78
Issue
3
Start Page
157
Other Pages
64; quiz 184-6
Notes
LR: 20151119; GR: R01 MH079402/MH/NIMH NIH HHS/United States; GR: R01 MH079402-01A2/MH/NIMH NIH HHS/United States; GR: R24 HD042828/HD/NICHD NIH HHS/United States; GR: R24 HD042828-10/HD/NICHD NIH HHS/United States; JID: 0376370; NIHMS99261; OID: NLM: NIH
Place of Publication
United States
ISSN/ISBN
0022-4391; 0022-4391
Accession Number
PMID: 18307611
Language
eng
SubFile
Comparative Study; Journal Article; IM; N
DOI
10.1111/j.1746-1561.2007.00278.x [doi]
Output Language
Unknown(0)
PMID
18307611
Abstract
BACKGROUND: Depression is prevalent among children and adolescents and often goes untreated with adverse effects on academic success and healthy development. Depression screening can facilitate early identification and timely referral to prevention and treatment programs. Conducting school-based emotional health screening, however, raises the controversial issue of how to obtain informed parental permission. METHODS: During implementation of a depression screening program in an urban school district in the Pacific Northwest, the district's parental permission protocol changed from passive (information provided to parents via a school mailer with parents having the option to actively decline their child's participation) to active (information provided to parents via a school mailer requiring the written permission of the parents for their child's participation). This change provided an opportunity to examine differences in participation under these 2 conditions. RESULTS: A total of 1533 students were enrolled in this program across both years. Compared to conditions of passive permission, participation was dramatically reduced when children were required to have written parental permission, dropping from 85% to 66% of eligible children. Furthermore, under conditions of active parental permission, participation decreased differentially among student subgroups with increased risk for depression. CONCLUSIONS: Successful implementation of school-based emotional health screening programs requires careful consideration of how to inform and obtain permission from parents.
Descriptors
Adult, Child, Child Behavior/psychology, Correspondence as Topic, Depression/diagnosis, Education, Continuing, Ethnic Groups, Female, Humans, Male, Mass Screening, Middle Aged, Parental Consent/psychology, Parental Notification, Parents/psychology, Patient Compliance/statistics & numerical data, School Health Services, Schools, Students/psychology, Surveys and Questionnaires, Urban Population, Washington
Links
Book Title
Database
Publisher
Data Source
Authors
Chartier,M., Stoep,A. V., McCauley,E., Herting,J. R., Tracy,M., Lymp,J.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC2713664
Editors