WTS database

Title	Pub Year	Author	SearchLink Sort ascending
Hookah use among adolescents in the United States: results of a national survey	2014	Department of Pediatrics, New York University School of Medicine, New York, NY;	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Periodical, Abbrev. Nicotine Tob.Res. Pub Date Free Form Feb Volume 16 Issue 2 Start Page 231 Other Pages 237 Notes JID: 9815751; 2013/10/23 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-994X; 1462-2203 Accession Number PMID: 24154512 Language eng SubFile Journal Article; IM DOI 10.1093/ntr/ntt160 [doi] Output Language Unknown(0) PMID 24154512 Abstract INTRODUCTION: U.S. adolescents increasingly use alternative tobacco products (ATPs), including hookah. No study has previously assessed correlates of adolescent hookah use in a nationally representative sample. METHODS: Cross-sectional, nationally representative data of adolescents from the 2011 National Youth Tobacco Survey (NYTS) were used. Student demographics and their use of, exposure to, and beliefs about tobacco were examined as correlates of hookah use. RESULTS: Of adolescents nationwide, 7.3% reported ever trying hookah and 2.6% reported using hookah within the past month. Increasing age was associated with trying hookah, but not current hookah use. Sex was unassociated with hookah use. Asians were most likely to have tried hookah; Hispanics and those of another race reported greater current hookah use. Hookah use increased with perceived ease of access to and willingness to try tobacco. Students with a hookah user at home were more likely to have tried hookah and to currently use hookah. Current cigarette use was not associated with current hookah use (odds ratio [OR] = 1.3, 95% CI = 0.8-2.1), but was associated with trying hookah (OR = 1.5, 95% CI = 1.1-2.2). Non-cigarette tobacco use was associated with trying hookah (OR = 2.7, 95% CI = 2.1-3.5) and current hookah use (OR = 4.8, 95% CI = 2.7-8.7). CONCLUSIONS: A sizeable minority of U.S. adolescents use hookah, particularly those living with hookah users, those who use other ATPs, and those who perceive tobacco as easily accessible. Current cigarette use was not associated with current hookah use. Future studies assessing the dangers of hookah use and interventions to curb this emerging problem appear warranted. Descriptors Links Book Title Database Publisher Data Source Authors Amrock,S.M., Gordon,T., Zelikoff,J.T., Weitzman,M. Original/Translated Title URL Date of Electronic 20131023 PMCID Editors
Carbon nanotubes reinforced hollow fiber solid phase microextraction for the determination of strychnine and brucine in urine	2013	Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China; University of Chinese Academy of Sciences,	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Talanta Periodical, Abbrev. Talanta Pub Date Free Form 15-Nov Volume 116 Issue Start Page 188 Other Pages 194 Notes CI: (c) 2013; JID: 2984816R; 0 (Membranes, Artificial); 0 (Nanotubes, Carbon); 6NG17YCK6H (brucine); H9Y79VD43J (Strychnine); NV1779205D (1-Octanol); OTO: NOTNLM; 2013/03/01 [received]; 2013/05/09 [revised]; 2013/05/11 [accepted]; 2013/05/16 [aheadofprint Place of Publication Netherlands ISSN/ISBN 1873-3573; 0039-9140 Accession Number PMID: 24148391 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.talanta.2013.05.025 [doi] Output Language Unknown(0) PMID 24148391 Abstract A mixed matrix membrane (MMM), based on carbon nanotubes (CNTs) and hollow fiber (HF), was prepared and combined with solid phase microextraction (SPME) mode to determine strychnine and brucine in urine. This MMM was prepared by dispersing CNTs in water via surfactant assistance, and then immobilizing CNTs into the pores of HF by capillary forces and sonification. The prepared carbon nanotubes reinforced hollow fiber (CNTs-HF) was subsequently wetted by a few microliters of organic solvent (1-octanol), and then applied to extract the target analytes in direct immersion sampling mode. After extraction, analytes were desorbed via ultrasonic-assisted effect, and then detected via high-performance liquid chromatography (HPLC). To achieve the highest extraction efficiency, main extraction parameters such as the type and amount of surfactant, the diameter and doping level of CNTs, extraction time, desorption condition, pH value, stirring rate and volume of the donor phase were optimized. Under the optimum extraction conditions, the method showed good linearity ranges with correlation coefficients higher than 0.9990, good repeatability and batch-to-batch reproducibility with relative standard deviations (RSDs) less than 6% and 5% for strychnine and brucine, respectively, and low limits of detection (0.7 and 0.9 microg L(-1) for strychnine and brucine, respectively). The recoveries were in the range of 83.81-116.14% at three spiked levels. The developed method was successfully applied to real urine sample with mean relative recoveries of 94.28% and 91.30% for strychnine and brucine, respectively. The developed method shows comparable results against reference methods and is a simple, green, and cost-effective microextraction technique. Descriptors Links Book Title Database Publisher Elsevier B.V Data Source Authors Song,X.Y., Shi,Y.P., Chen,J. Original/Translated Title URL Date of Electronic 20130516 PMCID Editors
Hookah pipe smoking among health sciences students	2013	Faculty of Health Sciences, University of Cape Town, South Africa. nicolina.vandermerwe@gmail.com.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Periodical, Abbrev. S.Afr.Med.J. Pub Date Free Form 30-Sep Volume 103 Issue 11 Start Page 847 Other Pages 849 Notes LR: 20151119; JID: 0404520; 2013/08/31 [received]; 2013/09/05 [accepted]; epublish Place of Publication South Africa ISSN/ISBN 0256-9574 Accession Number PMID: 24148170 Language eng SubFile Journal Article; IM DOI 10.7196/samj.7448 [doi] Output Language Unknown(0) PMID 24148170 Abstract BACKGROUND: Hookah pipe smoking is a social practice and has gained popularity, especially among South African youth. The extent of this practice among health sciences students, and their knowledge regarding the health risks, are unknown. This is important, as these students will become future health professionals possibly influencing the practice of individuals and communities. OBJECTIVE: To explore the knowledge, attitudes and practices of hookah pipe smoking among students at the Faculty of Health Sciences, University of Cape Town. METHODS. A cross-sectional study was conducted among undergraduate and postgraduate students. A self-administered questionnaire was distributed as a hard copy and online survey. RESULTS: Of 228 participants, 66% had smoked a hookah pipe before, with 18% still smoking. Most began smoking in high school, with 25% initiating at university. Of the current smokers, 65% smoked occasionally socially, commonly at friends' houses for 30 - 60 min/session. A further 11% smoked cigarettes concurrently and 30% added other substances, mainly cannabis, to pipes. Most current hookah smokers had no interest in quitting (84%). Only 30% of participants had prior health information about hookah pipe smoking. Most knew that it was harmful (91%), with many not knowing why. A total of 80% of participants perceived that the practice was socially acceptable and 84% would recommend it to others.CONCLUSION; The poor knowledge about the dangers of hookah pipe smoking and the extent of its practice among health sciences students is alarming. These findings highlight the need for school and university health promotion campaigns, and for better regulation of hookah pipe smoking. Descriptors Links Book Title Database Publisher Data Source Authors van der Merwe,N., Banoobhai,T., Gqweta,A., Gwala,A., Masiea,T., Misra,M., Zweigenthal,V. Original/Translated Title URL Date of Electronic 20130930 PMCID Editors
Is consumer response to plain/standardised tobacco packaging consistent with framework convention on tobacco control guidelines? A systematic review of quantitative studies	2013	Institute for Social Marketing & Cancer Research United Kingdom Centre for Tobacco Control Research and United Kingdom Centre for Tobacco and Alcohol Studies, University of Stirling, Stirling, United Kingdom.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PloS one Periodical, Abbrev. PLoS One Pub Date Free Form 16-Oct Volume 8 Issue 10 Start Page e75919 Other Pages Notes LR: 20150708; GR: MR/K023195/1/Medical Research Council/United Kingdom; GR: British Heart Foundation/United Kingdom; GR: Department of Health/United Kingdom; GR: Medical Research Council/United Kingdom; JID: 101285081; OID: NLM: PMC3797796; 2013 [ecollect Place of Publication United States ISSN/ISBN 1932-6203; 1932-6203 Accession Number PMID: 24146791 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; Review; IM DOI 10.1371/journal.pone.0075919 [doi] Output Language Unknown(0) PMID 24146791 Abstract BACKGROUND AND OBJECTIVES: Standardised or 'plain' tobacco packaging was introduced in Australia in December 2012 and is currently being considered in other countries. The primary objective of this systematic review was to locate, assess and synthesise published and grey literature relating to the potential impacts of standardised tobacco packaging as proposed by the guidelines for the international Framework Convention on Tobacco Control: reduced appeal, increased salience and effectiveness of health warnings, and more accurate perceptions of product strength and harm. METHODS: Electronic databases were searched and researchers in the field were contacted to identify studies. Eligible studies were published or unpublished primary research of any design, issued since 1980 and concerning tobacco packaging. Twenty-five quantitative studies reported relevant outcomes and met the inclusion criteria. A narrative synthesis was conducted. RESULTS: Studies that explored the impact of package design on appeal consistently found that standardised packaging reduced the appeal of cigarettes and smoking, and was associated with perceived lower quality, poorer taste and less desirable smoker identities. Although findings were mixed, standardised packs tended to increase the salience and effectiveness of health warnings in terms of recall, attention, believability and seriousness, with effects being mediated by the warning size, type and position on pack. Pack colour was found to influence perceptions of product harm and strength, with darker coloured standardised packs generally perceived as containing stronger tasting and more harmful cigarettes than fully branded packs; lighter coloured standardised packs suggested weaker and less harmful cigarettes. Findings were largely consistent, irrespective of location and sample. CONCLUSIONS: The evidence strongly suggests that standardised packaging will reduce the appeal of packaging and of smoking in general; that it will go some way to reduce consumer misperceptions regarding product harm based upon package design; and will help make the legally required on-pack health warnings more salient. Descriptors Links Book Title Database Publisher Data Source Authors Stead,M., Moodie,C., Angus,K., Bauld,L., McNeill,A., Thomas,J., Hastings,G., Hinds,K., O'Mara-Eves,A., Kwan,I., Purves,R.I., Bryce,S.L. Original/Translated Title URL Date of Electronic 20131016 PMCID PMC3797796 Editors
Tobacco use in older adults in Ghana: sociodemographic characteristics, health risks and subjective wellbeing	2013	Department of Community Health, University of Ghana Medical School, College of Health Sciences, Room 46, P, O, Box 4236, Korle-Bu, Accra, Ghana. aeyawson@yahoo.com.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC public health Periodical, Abbrev. BMC Public Health Pub Date Free Form 20-Oct Volume 13 Issue Start Page 979 Other Pages 2458-13-979 Notes GR: OGHA 04034785/PHS HHS/United States; GR: R01 AG034479-64401A1/AG/NIA NIH HHS/United States; GR: Y1-AG-1005-01/AG/NIA NIH HHS/United States; GR: YA1323-08-CN-0020/CN/NCI NIH HHS/United States; JID: 100968562; OID: NLM: PMC3924352; 2013/08/14 [received] Place of Publication England ISSN/ISBN 1471-2458; 1471-2458 Accession Number PMID: 24138966 Language eng SubFile Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1186/1471-2458-13-979 [doi] Output Language Unknown(0) PMID 24138966 Abstract BACKGROUND: Tobacco use over the life-course threatens to increase disease burden in older adulthood, including lower income countries like Ghana. This paper describes demographic, socioeconomic, health risks and life satisfaction indices related to tobacco use among older adults in Ghana. METHODS: This work was based on the World Health Organization's multi-country Study on global AGEing and adult health (SAGE), conducted in six countries including Ghana. Wave one of SAGE in Ghana was conducted in 2007-2008 as collaboration between WHO and the University of Ghana Medical School through the Department of Community Health. A nationally representative sample of 4305 older adults aged 50 years and above were interviewed. Associations between tobacco consumption and sociodemographic, socioeconomic, health risk and life satisfaction were evaluated using chi-square and odds ratio (OR). Logistic regression analyses, adjusted for age, sex and other variables, were conducted to determine predictors of tobacco consumption in older persons. RESULTS: Overall prevalence of current daily smokers among older adults in Ghana was 7.6%. Tobacco use (i.e. ever used tobacco) was associated with older males, (AOR = 1.10, CI 1.05-1.15), older adults residing in rural locations (AOR = 1.37, CI 1.083-1.724), and older adults who used alcohol (AOR = 1.13, CI 0.230-2.418). Tobacco use was also associated (although not statistically significant per p-values) with increased self-reporting of angina, arthritis, asthma, chronic lung disease, depression, diabetes, hypertension, and stroke. Older adults who used tobacco and with increased health risks, tended to be without health insurance (AOR = 1.41, CI 1.111-1.787). Satisfaction with life and daily living was much lower for those who use tobacco. Regional differences existed in tobacco use; the three northern regions (Upper East, Northern and Upper West) had higher proportions of tobacco use among older adults in the country. Quitting tobacco use was higher in the 70+ years age group, in women, among urban residents and in those with at least secondary education. Quitting tobacco use also increased with increasing income levels. CONCLUSIONS: Tobacco use among older adults in Ghana was associated with older men living in rural locations, chronic ill-health and reduced life satisfaction. A high proportion of older adults have stopped using tobacco, demonstrating the possibilities for effective public health interventions. Health risk reduction strategies through targeted anti-smoking health campaigns, improvement in access to health and social protection (such as health insurance) will reduce health risks among older persons who use tobacco. Descriptors Links Book Title Database Publisher Data Source Authors Yawson,A.E., Baddoo,A., Hagan-Seneadza,N.A., Calys-Tagoe,B., Hewlett,S., Dako-Gyeke,P., Mensah,G., Minicuci,N., Naidoo,N., Chatterji,S., Kowal,P., Biritwum,R. Original/Translated Title URL Date of Electronic 20131020 PMCID PMC3924352 Editors
Depression in smoking pregnant women: impact on motivation to quit smoking	2014	Service de maternite, groupe hospitalier mutualiste de Grenoble, 38000 Grenoble, France.; Institut Rhone-Alpes Auvergne de tabacologie (IRAAT), hopital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69004 Lyon, France; Dispensaire Emile-Roux, 11,	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal de gynecologie, obstetrique et biologie de la reproduction Periodical, Abbrev. J.Gynecol.Obstet.Biol.Reprod.(Paris) Pub Date Free Form Nov Volume 43 Issue 9 Start Page 691 Other Pages 697 Notes CI: Copyright (c) 2013; JID: 0322206; OTO: NOTNLM; 2013/07/01 [received]; 2013/09/09 [revised]; 2013/09/13 [accepted]; 2013/10/14 [aheadofprint]; ppublish Place of Publication France ISSN/ISBN 1773-0430; 0150-9918 Accession Number PMID: 24135016 Language fre SubFile English Abstract; Journal Article; Multicenter Study; IM DOI 10.1016/j.jgyn.2013.09.005 [doi] Output Language Unknown(0) PMID 24135016 Abstract Despite the organization of smoking cessation program, the percentage of pregnant smokers remains too high in France. The knowledge of the factors limiting success of the attempt can help the smoking cessation. AIM: To evaluate the prevalence of depressive disorders in pregnant smokers compared to nonsmokers; assess their impact on motivation stopping smoking; verify their identification can be performed by midwives. MATERIALS AND METHODS: Prospective multicenter survey on 792 women (435 smokers and 357 non-smokers), the assessment of the current depression is made by the Hospital Anxiety Depression scale, and motivation to quit smoking by the Richmond test. RESULTS: Pregnant smokers compared to non-smokers, have more frequent depressive disorders (current: OR=2.4; history: OR=2). These problems do not decrease the motivation to quit, they are associated with a high nicotine dependence and low socioeconomic levels. Their testing can be done by midwives. CONCLUSION: Systematic screening for depression in pregnant women smoking could facilitate smoking cessation. Descriptors Links Book Title Database Publisher Elsevier Masson SAS Data Source Authors Dupre,F., Perriot,J., Defay,I., Lavessiere,C., Defay,F., Guillon,C., Mathern,G., Berland,M. Original/Translated Title Depression chez la femme enceinte fumeuse : impact sur la motivation a l'arret du tabac URL Date of Electronic 20131014 PMCID Editors
Minnesota smokers' perceived helpfulness of 2009 federal tobacco tax increase in assisting smoking cessation: a prospective cohort study	2013	Division of Epidemiology and Community Health, University of Minnesota, 1300 South Second Street # 300, Minneapolis, MN 55454, USA. Choix137@umn.edu.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC public health Periodical, Abbrev. BMC Public Health Pub Date Free Form 18-Oct Volume 13 Issue Start Page 965 Other Pages 2458-13-965 Notes LR: 20151119; JID: 100968562; OID: NLM: PMC3853445; 2013/07/24 [received]; 2013/10/14 [accepted]; 2013/10/18 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1471-2458; 1471-2458 Accession Number PMID: 24134094 Language eng SubFile Journal Article; IM DOI 10.1186/1471-2458-13-965 [doi] Output Language Unknown(0) PMID 24134094 Abstract BACKGROUND: The cost of cigarettes has been cited as a motivating factor for smokers to quit smoking, and a cigarette tax increase is an effective way to increase the cost of cigarettes. Scholars have suggested that smokers may see cigarette tax increases as commitment devices to help them quit smoking. Little is known about whether smokers actually think cigarette tax increases help them quit, and whether this perception predicts subsequent smoking cessation behaviors. We used data from the Minnesota Adult Tobacco Survey Cohort Study collected after the 2009 federal tobacco tax increase to answer these questions. METHODS: In 2009, 727 smokers were asked whether they thought the federal tobacco tax increase helped them to: (1) think about quitting, (2) cut down on cigarettes, and (3) make a quit attempt. We also collected data on demographics, number of cigarette price-minimizing strategies used, and cigarette consumption. In 2010, we assessed if these smokers had made a quit attempt, had cut down on their cigarette consumption, and had stopped smoking. Logistic regression models were used to assess the characteristics associated with the perceptions that the tax increase was helpful in assisting smoking cessation, and the association between these perceptions in 2009 and cessation behaviors in 2010. RESULTS: Overall, 65% of the sample thought that the 2009 tax increase helped them think about quitting, 47% thought it helped them cut down on cigarettes, and 29% thought it helped them make a quit attempt. Lower education, lower income, lower cigarette consumption, and using more cigarette price-minimizing strategies were associated with the perceptions that the tax increase was helpful in assisting smoking cessation (p Descriptors Links Book Title Database Publisher Data Source Authors Choi,K., Boyle,R.G. Original/Translated Title URL Date of Electronic 20131018 PMCID PMC3853445 Editors
Brief, instructional smokeless tobacco use among cigarette smokers who do not intend to quit: a pilot randomized clinical trial	2014	Department of Psychiatry and Behavioral Sciences and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC;	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Periodical, Abbrev. Nicotine Tob.Res. Pub Date Free Form Apr Volume 16 Issue 4 Start Page 397 Other Pages 405 Notes LR: 20160218; GR: T32 DA007288/DA/NIDA NIH HHS/United States; JID: 9815751; 0 (Nitrosamines); OID: NLM: PMC3954419; 2013/10/15 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-994X; 1462-2203 Accession Number PMID: 24130144 Language eng SubFile Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; IM DOI 10.1093/ntr/ntt161 [doi] Output Language Unknown(0) PMID 24130144 Abstract INTRODUCTION: Low-nitrosamine smokeless tobacco (SLT) may have efficacy for smoking reduction and cessation, but its public health impact depends on how smokers use it. METHODS: This pilot study explored brief, instructional low-nitrosamine SLT use among smokers unmotivated to quit. Participants (N = 57) were randomized to either a free 2-week supply of Camel Snus group or a no-supply group. Of those randomized to use Camel Snus, half were told to use it to cope with smoking restrictions (Snus to Cope), and the remaining half were advised to use it to reduce smoking (Snus to Reduce). Participants were assessed before, during, and immediately after the intervention. RESULTS: Many Snus to Cope and Snus to Reduce participants reported daily use of Camel Snus, although the amount of use was low. Snus to Cope (18.4%) and Snus to Reduce (37.6%) participants reported a decline in number of cigarettes used per day, which was not reported by the control participants (p Descriptors Links Book Title Database Publisher Data Source Authors Burris,J.L., Carpenter,M.J., Wahlquist,A.E., Cummings,K.M., Gray,K.M. Original/Translated Title URL Date of Electronic 20131015 PMCID PMC3954419 Editors
Impact of active and passive smoking as risk factors for asthma and COPD in women presenting to primary care in Syria: first report by the WHO-GARD survey group	2013	National Center for Research in Chronic Respiratory Diseases, Tishreen University School of Medicine, Latakia, Syria.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of chronic obstructive pulmonary disease Periodical, Abbrev. Int.J.Chron.Obstruct Pulmon Dis. Pub Date Free Form Volume 8 Issue Start Page 473 Other Pages 482 Notes LR: 20151119; JID: 101273481; 0 (Bronchodilator Agents); 0 (Tobacco Smoke Pollution); OID: NLM: PMC3794890; OTO: NOTNLM; 2013 [ecollection]; 2013/10/02 [epublish]; ppublish Place of Publication New Zealand ISSN/ISBN 1178-2005; 1176-9106 Accession Number PMID: 24124359 Language eng SubFile Journal Article; Multicenter Study; Observational Study; Video-Audio Media; IM DOI 10.2147/COPD.S50551 [doi] Output Language Unknown(0) PMID 24124359 Abstract BACKGROUND: The burden of chronic respiratory disease (CRD) is alarming. International studies suggest that women with CRD are undersurveyed and underdiagnosed by physicians worldwide. It is unclear what the prevalence of CRD is in the general population of Syria, particularly among women, since there has never been a survey on CRD in this nation. The purpose of this study was to investigate the impact of different patterns of smoking on CRD in women. MATERIALS AND METHODS: We extracted data on smoking patterns and outcome in women from the Global Alliance Against Chronic Respiratory Diseases survey. Using spirometric measurements before and after the use of inhaled bronchodilators, we tracked the frequency of CRD in females active and passive narghile or cigarette smokers presenting to primary care. We administered the questionnaire to 788 randomly selected females seen during 1 week in the fiscal year 2009-2010 in 22 primary care centers in six different regions of Syria. Inclusion criteria were age >6 years, presenting for any medical complaint. In this cross-sectional study, three groups of female subjects were evaluated: active smokers of cigarettes, active smokers of narghiles, and passive smokers of either cigarettes or narghiles. These three groups were compared to a control group of female subjects not exposed to active or passive smoking. RESULTS: Exposure to active cigarette smoke but not narghile smoke was associated with doctor-diagnosed chronic obstructive pulmonary disease (COPD). However, neither cigarette nor narghile active smoking was associated with increased incidence of spirometrically diagnosed COPD. Paradoxically, exposure to passive smoking of either cigarettes or narghiles resulted in association with airway obstruction, defined as forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) Descriptors Links Book Title Database Publisher Data Source Authors Mohammad,Y., Shaaban,R., Al-Zahab,B.A., Khaltaev,N., Bousquet,J., Dubaybo,B. Original/Translated Title URL Date of Electronic 20131002 PMCID PMC3794890 Editors
Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome	2013	Nicola de Bortoli, Irene Martinucci, Massimo Bellini, Santino Marchi, Division of Gastroenterology, University of Pisa, 56124 Pisa, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full World journal of gastroenterology Periodical, Abbrev. World J.Gastroenterol. Pub Date Free Form 21-Sep Volume 19 Issue 35 Start Page 5787 Other Pages 5797 Notes LR: 20151022; JID: 100883448; OID: NLM: PMC3793133; OTO: NOTNLM; 2012/09/24 [received]; 2012/11/14 [revised]; 2012/12/25 [accepted]; ppublish Place of Publication China ISSN/ISBN 2219-2840; 1007-9327 Accession Number PMID: 24124323 Language eng SubFile Journal Article; Review; IM DOI 10.3748/wjg.v19.i35.5787 [doi] Output Language Unknown(0) PMID 24124323 Abstract Several studies indicate a significant degree of overlap between irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). Likewise, both functional heartburn (FH) and IBS are functional digestive disorders that may occur in the same patients. However, data establishing a solid link between FH and IBS are lacking, mainly because the clinical definition of FH has undergone substantial changes over the years. The available literature on the overlap between GERD or FH and IBS highlights considerable heterogeneity in terms of the criteria and diagnostic procedures used to assess heartburn and IBS. In particular, several epidemiological studies included patients with concomitant IBS and GERD without any attempt to distinguish FH (as defined by the Rome III criteria) from GERD via pathophysiological investigations. Independent of these critical issues, there is preliminary evidence supporting a significant degree of FH-IBS overlap. This underscores the need for studies based on updated diagnostic criteria and accurate pathophysiological classifications, particularly to distinguish FH from GERD. This distinction would represent an essential starting point to achieving a better understanding of pathophysiology in the subclasses of patients with GERD and FH and properly assessing the different degrees of overlap between IBS and the subcategories of heartburn.The present review article intends to appraise and critically discuss current evidence supporting a possible concomitance of GERD or FH with IBS in the same patients and to highlight the pathophysiological relationships between these disorders. Descriptors Links Book Title Database Publisher Data Source Authors de Bortoli,N., Martinucci,I., Bellini,M., Savarino,E., Savarino,V., Blandizzi,C., Marchi,S. Original/Translated Title URL Date of Electronic PMCID PMC3793133 Editors

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