WTS database

Title	Pub Year	Author Sort descending	SearchLink
Intraskeletal isotopic compositions (delta(13) C, delta(15) N) of bone collagen: nonpathological and pathological variation	2014	Department of Anthropology, The University of Western Ontario, London, ON, Canada.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Physical Anthropology Periodical, Abbrev. Am.J.Phys.Anthropol. Pub Date Free Form Apr Volume 153 Issue 4 Start Page 598 Other Pages 604 Notes CI: Copyright (c) 2013; JID: 0400654; 0 (Carbon Isotopes); 0 (Nitrogen Isotopes); 9007-34-5 (Collagen); OTO: NOTNLM; 2012/09/30 [received]; 2013/12/11 [accepted]; 2013/12/30 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1096-8644; 0002-9483 Accession Number PMID: 24374993 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1002/ajpa.22459 [doi] Output Language Unknown(0) PMID 24374993 Abstract Paleodiet research traditionally interprets differences in collagen isotopic compositions (delta(13) C, delta(15) N) as indicators of dietary distinction even though physiological processes likely play some role in creating variation. This research investigates the degree to which bone collagen delta(13) C and delta(15) N values normally vary within the skeleton and examines the influence of several diseases common to ancient populations on these isotopic compositions. The samples derive from two medieval German cemeteries and one Swiss reference collection and include examples of metabolic disease (rickets/osteomalacia), degenerative joint disease (osteoarthritis), trauma (fracture), infection (osteomyelitis), and inflammation (periostitis). A separate subset of visibly nonpathological skeletal elements from the German collections established normal intraindividual variation. For each disease type, tests compared bone lesion samples to those near and distant to the lesions sites. Results show that normal (nonpathological) skeletons exhibit limited intraskeletal variation in carbon- and nitrogen-isotope ratios, suggesting that sampling of distinct elements is appropriate for paleodiet studies. In contrast, individuals with osteomyelitis, healed fractures, and osteoarthritis exhibit significant intraskeletal differences in isotope values, depending on whether one is comparing lesions to near or to distant sites. Skeletons with periostitis result in significant intraskeletal differences in nitrogen isotope values only, while those with rickets/osteomalacia do not exhibit significant intraskeletal differences. Based on these results, we suggest that paleodiet researchers avoid sampling collagen at or close to lesion sites because the isotope values may be reflecting both altered metabolic processes and differences in diet relative to others in the population. Descriptors Links Book Title Database Publisher Wiley Periodicals, Inc Data Source Authors Olsen,K.C., White,C.D., Longstaffe,F.J., von Heyking,K., McGlynn,G., Grupe,G., Ruhli,F.J. Original/Translated Title URL Date of Electronic 20131230 PMCID Editors
Diet and gender in the Tiwanaku colonies: Stable isotope analysis of human bone collagen and apatite from Moquegua, Peru	2015	Department of Anthropology, University of California, San Diego, La Jolla, CA, 92093-0532.; Department of Anthropology, University of California, San Diego, La Jolla, CA, 92093-0532.; Department of Anthropology, University of California, San Diego, La Jol	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Physical Anthropology Periodical, Abbrev. Am.J.Phys.Anthropol. Pub Date Free Form Nov Volume 158 Issue 3 Start Page 408 Other Pages 422 Notes CI: (c) 2015; JID: 0400654; 0 (Apatites); 0 (Carbon Isotopes); 0 (Nitrogen Isotopes); 9007-34-5 (Collagen); OTO: NOTNLM; 2014/08/11 [received]; 2015/05/31 [revised]; 2015/06/01 [accepted]; 2015/07/14 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1096-8644; 0002-9483 Accession Number PMID: 26173647 Language eng SubFile Journal Article; IM DOI 10.1002/ajpa.22795 [doi] Output Language Unknown(0) PMID 26173647 Abstract OBJECTIVES: Gender and other facets of social identity play important roles in the organization of complex societies. This study reconstructs dietary practices within the Middle Horizon (AD 500-1000) Tiwanaku colonies in southern Peru to increase our knowledge of gendered patterns of consumption within this early expansive state. METHODS: We use stable isotope analysis of 43 human bone samples representing 14 females, 20 males, 8 juveniles, and 1 indeterminate individual recovered from burial excavations at the sites of Rio Muerto and Omo in the Moquegua Valley. Data are contextualized by comparisons with previously published Tiwanaku isotope data from the period. RESULTS: Our results find mean values of delta(13) Capatite = -7.3 +/- 1.6% (N = 36, 1SD), delta(13) Ccollagen = -12.3 +/- 1.5% (N = 43, 1SD), and delta(15) Ncollagen = 8.4 +/- 1.6% (N = 43, 1SD). Between the sexes, Mann-Whitney U tests demonstrate significant differences in delta(13) Ccollagen (U = 74, P = 0.021), but no differences in delta(13) Capatite (U = 58, P = 0.095) or delta(15) Ncollagen (U = 116, P = 0.755) values. CONCLUSIONS: These data indicate relatively high C4 plant consumption among the Tiwanaku colonies, and support paleobotanical and archaeological evidence that maize (Zea mays) was the staple crop. Dietary values are similar overall between the sexes, but significantly higher delta(13) Ccollagen values in males is consistent with a model of gendered norms of consumption similar to that of the later Inca (AD 1438-1533), where males consumed more maize than females, often in the form of beer (chicha). Results provide new insights on social dynamics within the Tiwanaku colonies and suggest the increased importance maize consumption for males during the Tiwanaku expansion. Descriptors Links Book Title Database Publisher Wiley Periodicals, Inc Data Source Authors Somerville,A.D., Goldstein,P.S., Baitzel,S.I., Bruwelheide,K.L., Dahlstedt,A.C., Yzurdiaga,L., Raubenheimer,S., Knudson,K.J., Schoeninger,M.J. Original/Translated Title URL Date of Electronic 20150714 PMCID Editors
Local domestication of lactic acid bacteria via cassava beer fermentation	2014	Department of Anthropology, University of Oregon , Eugene, OR , USA ; Institute of Ecology and Evolution, University of Oregon , Eugene, OR , USA.; Institute of Ecology and Evolution, University of Oregon , Eugene, OR , USA.; Department of Anthropology, U	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full PeerJ Periodical, Abbrev. PeerJ Pub Date Free Form 8-Jul Volume 2 Issue Start Page e479 Other Pages Notes LR: 20140731; JID: 101603425; OID: NLM: PMC4103073; OTO: NOTNLM; 2014 [ecollection]; 2014/02/02 [received]; 2014/06/18 [accepted]; 2014/07/08 [epublish]; epublish Place of Publication United States ISSN/ISBN 2167-8359 Accession Number PMID: 25071997 Language eng SubFile Journal Article DOI 10.7717/peerj.479 [doi] Output Language Unknown(0) PMID 25071997 Abstract Cassava beer, or chicha, is typically consumed daily by the indigenous Shuar people of the Ecuadorian Amazon. This traditional beverage made from cassava tuber (Manihot esculenta) is thought to improve nutritional quality and flavor while extending shelf life in a tropical climate. Bacteria responsible for chicha fermentation could be a source of microbes for the human microbiome, but little is known regarding the microbiology of chicha. We investigated bacterial community composition of chicha batches using Illumina high-throughput sequencing. Fermented chicha samples were collected from seven Shuar households in two neighboring villages in the Morona-Santiago region of Ecuador, and the composition of the bacterial communities within each chicha sample was determined by sequencing a region of the 16S ribosomal gene. Members of the genus Lactobacillus dominated all samples. Significantly greater phylogenetic similarity was observed among chicha samples taken within a village than those from different villages. Community composition varied among chicha samples, even those separated by short geographic distances, suggesting that ecological and/or evolutionary processes, including human-mediated factors, may be responsible for creating locally distinct ferments. Our results add to evidence from other fermentation systems suggesting that traditional fermentation may be a form of domestication, providing endemic beneficial inocula for consumers, but additional research is needed to identify the mechanisms and extent of microbial dispersal. Descriptors Links Book Title Database Publisher Data Source Authors Colehour,A.M., Meadow,J.F., Liebert,M.A., Cepon-Robins,T.J., Gildner,T.E., Urlacher,S.S., Bohannan,B.J., Snodgrass,J.J., Sugiyama,L.S. Original/Translated Title URL Date of Electronic 20140708 PMCID PMC4103073 Editors
Fungi from a Groundwater-Fed Drinking Water Supply System in Brazil	2016	Department of Antibiotics, Federal University of Pernambuco, Av. Prof. Morais Rego, 1235, Recife, Pernambuco 50670-901, Brazil. helenambo@yahoo.com.br.; Department of Chemical Sciences and Natural Resources, BIOREN-UFRO Scientific and Technological Biores	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of environmental research and public health Periodical, Abbrev. Int.J.Environ.Res.Public.Health. Pub Date Free Form 9-Mar Volume 13 Issue 3 Start Page 10.3390/ijerph13030304 Other Pages Notes LR: 20160405; JID: 101238455; OID: NLM: PMC4808967; OTO: NOTNLM; 2016/02/11 [received]; 2016/02/28 [revised]; 2016/03/04 [accepted]; epublish Place of Publication Switzerland ISSN/ISBN 1660-4601; 1660-4601 Accession Number PMID: 27005653 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.3390/ijerph13030304 [doi] Output Language Unknown(0) PMID 27005653 Abstract Filamentous fungi in drinking water distribution systems are known to (a) block water pipes; (b) cause organoleptic biodeterioration; (c) act as pathogens or allergens and (d) cause mycotoxin contamination. Yeasts might also cause problems. This study describes the occurrence of several fungal species in a water distribution system supplied by groundwater in Recife-Pernambuco, Brazil. Water samples were collected from four sampling sites from which fungi were recovered by membrane filtration. The numbers in all sampling sites ranged from 5 to 207 colony forming units (CFU)/100 mL with a mean value of 53 CFU/100 mL. In total, 859 isolates were identified morphologically, with Aspergillus and Penicillium the most representative genera (37% and 25% respectively), followed by Trichoderma and Fusarium (9% each), Curvularia (5%) and finally the species Pestalotiopsis karstenii (2%). Ramichloridium and Leptodontium were isolated and are black yeasts, a group that include emergent pathogens. The drinking water system in Recife may play a role in fungal dissemination, including opportunistic pathogens. Descriptors Links Book Title Database Publisher Data Source Authors Oliveira,H.M., Santos,C., Paterson,R.R., Gusmao,N.B., Lima,N. Original/Translated Title URL Date of Electronic 20160309 PMCID PMC4808967 Editors
Prevalence, social acceptance, and awareness of waterpipe smoking among dental university students: a cross sectional survey conducted in Jordan	2014	Department of Applied Dental Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan. saobeidat@just.edu.jo.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full BMC research notes Periodical, Abbrev. BMC Res.Notes Pub Date Free Form 24-Nov Volume 7 Issue Start Page 832 Other Pages 0500-7-832 Notes LR: 20151028; JID: 101462768; OID: NLM: PMC4253988; 2014/07/01 [received]; 2014/11/18 [accepted]; 2014/11/24 [aheadofprint]; epublish Place of Publication England ISSN/ISBN 1756-0500; 1756-0500 Accession Number PMID: 25421621 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1186/1756-0500-7-832 [doi] Output Language Unknown(0) PMID 25421621 Abstract BACKGROUND: Waterpipe tobacco smoking is increasing in popularity especially among young adults. This spread could be related to limited knowledge of the negative health effects of waterpipe smoking. In this study, prevalence, social acceptance, and awareness of waterpipe smoking were examined among dental university students. METHODS: This is a cross-sectional survey study, where a self-administered questionnaire was completed by a sample of dental university students in Jordan. RESULTS: Students (n=547) reported current tobacco use of 54.3% for males versus 11.1% for females (P Descriptors Links Book Title Database Publisher Data Source Authors Obeidat,S.R., Khabour,O.F., Alzoubi,K.H., Mahasneh,A.M., Bibars,A.R., Khader,Y.S., Alsa'di,A. Original/Translated Title URL Date of Electronic 20141124 PMCID PMC4253988 Editors
Association between exposure to secondhand smoke during pregnancy and low birthweight: a narrative review	2015	Department of Applied Health Sciences, College of Nursing, Health, and Human Services, Indiana State University, Terre Haute, Indiana.; Division of Respiratory Therapy, School of Health Professions, Georgia State University, Atlanta, Georgia. oliver2387@b	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Respiratory care Periodical, Abbrev. Respir.Care Pub Date Free Form Jan Volume 60 Issue 1 Start Page 135 Other Pages 140 Notes CI: Copyright (c) 2015; JID: 7510357; 0 (Tobacco Smoke Pollution); OTO: NOTNLM; 2014/07/08 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1943-3654; 0020-1324 Accession Number PMID: 25006271 Language eng SubFile Journal Article; Review; IM DOI 10.4187/respcare.02798 [doi] Output Language Unknown(0) PMID 25006271 Abstract Exposure to secondhand smoke (SHS) during pregnancy may have adverse effects on the mother and infant. This study investigates the association of maternal exposure to SHS with low birthweight (LBW) in infants. Smoking during pregnancy has been linked to multiple complications for both mother and infant. To examine association of LBW and environmental tobacco smoke exposure during pregnancy, we reviewed 20 articles. Articles were accessed using the following electronic databases: CINAHL Plus with full text (EBSCO), PubMed, Embase, and MEDLINE. The findings of this review revealed that maternal exposure to environmental smoke is correlated with LBW in infants as well as numerous other adverse effects. The majority of the studies found negative consequences of SHS on the birthweight of infants born to nonsmoking women. Thus, this review helps to confirm the association between maternal exposure to SHS and LBW in infants. Descriptors Links Book Title Database Publisher by Daedalus Enterprises Data Source Authors Hawsawi,A.M., Bryant,L.O., Goodfellow,L.T. Original/Translated Title URL Date of Electronic 20140708 PMCID Editors
6-{5-Amino-3-tert-butyl-4-[(E)-(3-methyl-1,2,4-thiadiazol-5-yl)diazen-yl]-1H-pyra zol-1-yl}-1,3,5-triazine-2,4(1H,3H)-dione-1-methyl-pyrrolidin-2-one-water (1/1/1)	2010	Department of Applied Physics, Graduate School of Engineering, Yokohama National University, Tokiwadai 79-5, Hodogaya-ku, Yokohama 240-8501, Japan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 27-Mar Volume 66 Issue Pt 4 Start Page o944 Other Pages 5 Notes LR: 20130314; JID: 101089178; OID: NLM: PMC2983887; 2010/03/18 [received]; 2010/03/23 [accepted]; 2010/03/27 [epublish]; epublish Place of Publication England ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 21580749 Language eng SubFile Journal Article DOI 10.1107/S1600536810010871 [doi] Output Language Unknown(0) PMID 21580749 Abstract In the title compound, C(13)H(16)N(10)O(2)S.C(5)H(9)NO.H(2)O, the entire 1-methylpyrrolidin-2-one (NMP) mol-ecule is disordered over two sites with occupancies of 0.488 (5) and 0.512 (5). The six-membered triazine ring and the two five-membered pyrazole and thiadia-zole rings, together with the diazene (-N=N-) linkage are almost coplanar (r.m.s. deviation for the non-H atoms = 0.0256 A) with methyl groups from the tert-butyl substituent on the pyrazole ring located above and below the plane. Three intra-molecular N-Hcdots, three dots, centeredN hydrogen bonds contribute to the planarity of the system. The O atom of the NMP mol-ecule is hydrogen bonded to an O-H group of water. In turn, the water mol-ecule is hydrogen bonded to the mono-azo skeleton through inter-molecular N-Hcdots, three dots, centeredO and O-Hcdots, three dots, centeredN hydrogen bonds. At both ends of the long mol-ecular axis of the main mol-ecule there are inter-molecular N-Hcdots, three dots, centeredN hydrogen bonds, arranged in a head-to-tail fashion, between the N-H group of the triazine ring of one mol-ecule and the N atom of the thia-diazole ring of a neighboring mol-ecule. These form a polymeric chain along [110] or [10]. The main mol-ecules are stacked alternately along the b axis, which effectively cancels their dipole moments. In addition, pairs of alternate molecules are dimerized via inter-molecular hydrogen bonds involving the solvent mol-ecules. Descriptors Links Book Title Database Publisher Data Source Authors Shibata,H., Mizuguchi,J. Original/Translated Title URL Date of Electronic 20100327 PMCID PMC2983887 Editors
Trend of Legionella colonization in hospital water supply	2015	Department of Architecture and Planning, Sapienza University of Rome, Italy.; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.; Medical Direction Unit, San Filippo Neri Hospital, Rome, Italy.; Department of Public H	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Annali di Igiene : Medicina Preventiva e di Comunita Periodical, Abbrev. Ann.Ig. Pub Date Free Form Mar-Apr Volume 27 Issue 2 Start Page 460 Other Pages 466 Notes JID: 9002865; OTO: NOTNLM; ppublish Place of Publication Italy ISSN/ISBN 1120-9135; 1120-9135 Accession Number PMID: 26051144 Language eng SubFile Journal Article; IM DOI 10.7416/ai.2015.2032 [doi] Output Language Unknown(0) PMID 26051144 Abstract BACKGROUND: In many nosocomial Legionella outbreaks water distribution systems are the most frequent source of infection. OBJECTIVES: Considering the hospital waterline old age, an investigation on colonization by Legionella spp was carried out in order to evaluate the pipeline system weaknesses and to implement environmental preventive measures. METHODS: From 2004 to 2010, overall 97 samples from the water line were collected. The samples were analyzed according to the italian Legionella spp standard methods; water temperature, pH and residual free chlorine were determined at the time of collection. X2 test, exact-test and t-test were used to compare proportions and means. RESULTS: Overall 28 samples (23.7%) were positive for Legionella spp, and five of them (17.9%) exceeded the threshold level >104 cfu/L. The number of positive samples varied along the years, showing a significant increasing trend (X2 for trend = 11.5; p104 cfu/L occurred in the C-building. No cases of nosocomial legionellosis were reported during the study period. CONCLUSIONS: Hospital water system showed a diffuse colonization by Legionella spp, although the degree of contamination reached the threshold level (>104 cfu/L) only in a small percentage of samples, showing a substantial effectiveness of the control measures applied. Descriptors Links Book Title Database Publisher Data Source Authors D'Alessandro,D., Fabiani,M., Cerquetani,F., Orsi,G.B. Original/Translated Title URL Date of Electronic PMCID Editors
Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation	2010	Department of Basic and Applied Medical Sciences, Ud'A Chieti-Pescara, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of applied physiology (Bethesda, Md.: 1985) Periodical, Abbrev. J.Appl.Physiol.(1985) Pub Date Free Form May Volume 108 Issue 5 Start Page 1077 Other Pages 1083 Notes LR: 20131121; JID: 8502536; 0 (ITGB3 protein, human); 0 (Integrin beta3); 0 (P-Selectin); 0 (Platelet Membrane Glycoprotein IIb); S88TT14065 (Oxygen); 2010/02/25 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1522-1601; 0161-7567 Accession Number PMID: 20185629 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1152/japplphysiol.01058.2009 [doi] Output Language Unknown(0) PMID 20185629 Abstract Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation in scuba divers was evaluated. Six volunteers participated in four diving protocols, with 2 wk of recovery between dives. On dive 1, before diving, all divers breathed normally for 20 min at the surface of the sea (Air). On dive 2, before diving, all divers breathed 100% oxygen for 20 min at the surface of the sea [normobaric oxygenation (NBO)]. On dive 3, before diving, all divers breathed 100% O2 for 20 min at 6 m of seawater [msw; hyperbaric oxygenation (HBO) 1.6 atmospheres absolute (ATA)]. On dive 4, before diving, all divers breathed 100% O2 for 20 min at 12 msw (HBO 2.2 ATA). Then they dove to 30 msw (4 ATA) for 20 min breathing air from scuba. After each dive, blood samples were collected as soon as the divers surfaced. Bubbles were measured at 20 and 50 min after decompression and converted to bubble count estimate (BCE) and numeric bubble grade (NBG). BCE and NBG were significantly lower in NBO than in Air [0.142+/-0.034 vs. 0.191+/-0.066 (P<0.05) and 1.61+/-0.25 vs. 1.89+/-0.31 (P<0.05), respectively] at 20 min, but not at 50 min. HBO at 1.6 ATA and 2.2 ATA has a similar significant effect of reducing BCE and NBG. BCE was 0.067+/-0.026 and 0.040+/-0.018 at 20 min and 0.030+/-0.022 and 0.020+/-0.020 at 50 min. NBG was 1.11+/-0.17 and 0.92+/-0.16 at 20 min and 0.83+/-0.18 and 0.75+/-0.16 at 50 min. Prebreathing NBO and HBO significantly alleviated decompression-induced platelet activation. Activation of CD62p was 3.0+/-0.4, 13.5+/-1.3, 10.7+/-0.9, 4.5+/-0.7, and 7.6+/-0.8% for baseline, Air, NBO, HBO at 1.6 ATA, and HBO at 2.2 ATA, respectively. The data show that prebreathing oxygen, more effective with HBO than NBO, decreases air bubbles and platelet activation and, therefore, may be beneficial in reducing the development of decompression sickness. Descriptors Administration, Inhalation, Adult, Decompression/adverse effects, Decompression Sickness/blood/physiopathology/prevention & control/ultrasonography, Diving, Embolism, Air/blood/physiopathology/prevention & control/ultrasonography, Humans, Hyperbaric Oxygenation, Immersion, Inhalation, Integrin beta3/blood, Male, Middle Aged, Oxygen/administration & dosage, P-Selectin/blood, Platelet Activation, Platelet Membrane Glycoprotein IIb/blood, Time Factors, Ultrasonography, Doppler, Young Adult Links Book Title Database Publisher Data Source Authors Bosco,G., Yang,Z. J., Di Tano,G., Camporesi,E. M., Faralli,F., Savini,F., Landolfi,A., Doria,C., Fano,G. Original/Translated Title URL Date of Electronic 20100225 PMCID Editors
Assessment of genotoxicity of waterpipe smoking using 8-OHdG biomarker	2015	Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa, Jordan azabmohd@yahoo.com.; Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, Jordan.; Department of Clinical Pharmacy	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Genetics and molecular research : GMR Periodical, Abbrev. Genet.Mol.Res. Pub Date Free Form 14-Aug Volume 14 Issue 3 Start Page 9555 Other Pages 9561 Notes JID: 101169387; 0 (Biomarkers); 0 (Mutagens); 88847-89-6 (8-oxo-7-hydrodeoxyguanosine); G9481N71RO (Deoxyguanosine); epublish Place of Publication Brazil ISSN/ISBN 1676-5680; 1676-5680 Accession Number PMID: 26345888 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.4238/2015.August.14.18 [doi] Output Language Unknown(0) PMID 26345888 Abstract Waterpipe tobacco smoking is increasing in popularity, particularly among young adults. This popularity is related to the lack knowledge regarding the health effects of waterpipe smoking. In this study, we examined the genotoxicity of waterpipe smoking using an 8-hydroxy deoxyguanosine (8-OHdG) assay. Genotoxicity was evaluated in the saliva, urine, and serum of 66 waterpipe adult smokers and 46 healthy nonsmokers. The level of addiction to waterpipe smoking was evaluated using the Lebanon Waterpipe Dependence Scale-11. Levels of 8-OHdG in the samples were measured using commercially available enzyme-linked immunosorbent assays. Levels of 8-OHdG in the saliva (52,430 +/- 2923 vs 48,430 +/- 4189 pg/mL), urine (2815 +/- 312 vs 2608 +/- 180 pg/mL), and serum (19,720 +/- 202 vs 19,670 +/- 254 pg/mL) were similar between waterpipe smokers and nonsmokers (P > 0.05). In addition, no correlations were found between dependence score and levels of 8-OHdG in all sample types. In conclusion, 8-OHdG is not a good biomarker for genotoxic effect of waterpipe smoking. Descriptors Links Book Title Database Publisher Data Source Authors Azab,M., Khabour,O.F., Alzoubi,K.H., Mahmoud,S.A., Anabtawi,M., Quttina,M. Original/Translated Title URL Date of Electronic 20150814 PMCID Editors

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