WTS database

Title	Pub Year Sort descending	Author	SearchLink
In vitro evaluation of antibiotic lock technique for the treatment of Candida albicans, C. glabrata, and C. tropicalis biofilms	2010	Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of Korean medical science Periodical, Abbrev. J.Korean Med.Sci. Pub Date Free Form Dec Volume 25 Issue 12 Start Page 1722 Other Pages 1726 Notes LR: 20150205; JID: 8703518; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Pyrimidines); 0 (Triazoles); 304NUG5GF4 (Itraconazole); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole); OID: NLM: PMC29952 Place of Publication Korea (South) ISSN/ISBN 1598-6357; 1011-8934 Accession Number PMID: 21165285 Language eng SubFile Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.3346/jkms.2010.25.12.1722 [doi] Output Language Unknown(0) PMID 21165285 Abstract Candidaemia associated with intravascular catheter-associated infections is of great concern due to the resulting high morbidity and mortality. The antibiotic lock technique (ALT) was previously introduced to treat catheter-associated bacterial infections without removal of catheter. So far, the efficacy of ALT against Candida infections has not been rigorously evaluated. We investigated in vitro activity of ALT against Candida biofilms formed by C. albicans, C. glabrata, and C. tropicalis using five antifungal agents (caspofungin, amphotericin B, itraconazole, fluconazole, and voriconazole). The effectiveness of antifungal treatment was assayed by monitoring viable cell counts after exposure to 1 mg/mL solutions of each antibiotic. Fluconazole, itraconazole, and voriconazole eliminated detectable viability in the biofilms of all Candida species within 7, 10, and 14 days, respectively, while caspofungin and amphotericin B did not completely kill fungi in C. albicans and C. glabrata biofilms within 14 days. For C. tropicalis biofilm, caspofungin lock achieved eradication more rapidly than amphotericin B and three azoles. Our study suggests that azoles may be useful ALT agents in the treatment of catheter-related candidemia. Descriptors Amphotericin B/administration & dosage/pharmacology, Antifungal Agents/administration & dosage/pharmacology/therapeutic use, Biofilms/drug effects, Candida albicans/drug effects/physiology, Candida glabrata/drug effects/physiology, Candida tropicalis/drug effects/physiology, Candidiasis/drug therapy, Catheter-Related Infections/drug therapy, Catheterization, Central Venous, Drug Administration Routes, Echinocandins/administration & dosage/pharmacology, Fluconazole/administration & dosage/pharmacology, Humans, Itraconazole/administration & dosage/pharmacology, Microbial Sensitivity Tests, Pyrimidines/administration & dosage/pharmacology, Triazoles/administration & dosage/pharmacology, Voriconazole, Antibiotic Lock Technique, Biofilms, Candida Links Book Title Database Publisher Data Source Authors Ko,K. S., Lee,J. Y., Song,J. H., Peck,K. R. Original/Translated Title URL Date of Electronic 20101124 PMCID PMC2995224 Editors
Metabolic syndrome and angiographic coronary artery disease prevalence in association with the Framingham risk score	2010	First Cardiology Department, AHEPA University Hospital, Aristotle University Medical School, Thessaloniki, Greece.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Metabolic syndrome and related disorders Periodical, Abbrev. Metab.Syndr.Relat.Disord. Pub Date Free Form Jun Volume 8 Issue 3 Start Page 201 Other Pages 208 Notes JID: 101150318; ppublish Place of Publication United States ISSN/ISBN 1557-8518; 1540-4196 Accession Number PMID: 20156070 Language eng SubFile Journal Article; IM DOI 10.1089/met.2009.0059 [doi] Output Language Unknown(0) PMID 20156070 Abstract BACKGROUND: The association of metabolic syndrome with coronary artery disease (CAD) has been studied extensively. However, little is known about the effect of Framingham risk score (FRS) and metabolic syndrome components on the association of metabolic syndrome with angiographically significant CAD. Our aim was to investigate whether that relationship is influenced by individual's 10-year CAD risk profile as assessed by FRS. Furthermore, we sought to elucidate whether metabolic syndrome is associated with angiographically significant CAD independently of its individual components. METHODS: We studied a consecutive sample of 150 patients undergoing coronary angiography for the evaluation of chest pain. Metabolic syndrome was defined according to the revised National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria, and the 10-year CAD risk was estimated by the FRS. RESULTS: Metabolic syndrome patients had a 2-fold higher CAD prevalence compared to those without metabolic syndrome [odds ratio (OR), 2.004; 95% confidence interval (CI), 1.029-3.905] but this finding was attenuated after adjustment for FRS (OR, 1.770; 95% CI, 0.872-3.594). Stratification of patients into three groups according to FRS revealed that metabolic syndrome predictive ability was confined in those being at <10% 10-year CAD risk. Including metabolic syndrome and its individual components into the same logistic regression model, only the glucose criterion was an independent predictor of angiographically significant CAD (OR, 4.137; 95% CI, 1.477-11.583). CONCLUSIONS: Metabolic syndrome is an independent determinant of angiographically significant CAD only among those individuals at low 10-year risk for future coronary events. Individual components of the syndrome, such as impaired fasting glucose, have a stronger association with CAD than the syndrome as a whole. Descriptors Aged, Chi-Square Distribution, Coronary Angiography, Coronary Artery Disease/epidemiology/etiology/radiography, Cross-Sectional Studies, Female, Greece/epidemiology, Humans, Logistic Models, Male, Metabolic Syndrome X/complications/diagnosis/epidemiology, Middle Aged, Odds Ratio, Prevalence, Risk Assessment, Risk Factors, Severity of Illness Index, Time Factors Links Book Title Database Publisher Data Source Authors Konstantinou,D. M., Chatzizisis,Y. S., Louridas,G. E., Giannoglou,G. D. Original/Translated Title URL Date of Electronic PMCID Editors
Identification of lactic acid bacteria associated with the production of plaa-som, a traditional fermented fish product of Thailand	2010	Graduate School, Department of Biotechnology, Khon Kaen University, Khon Kaen 40002, Thailand.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of food microbiology Periodical, Abbrev. Int.J.Food Microbiol. Pub Date Free Form 15-Apr Volume 138 Issue 3 Start Page 200 Other Pages 204 Notes CI: (c) 2009; JID: 8412849; 0 (DNA, Bacterial); 0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S); 2008/06/24 [received]; 2009/12/31 [revised]; 2010/01/17 [accepted]; 2010/01/28 [aheadofprint]; ppublish Place of Publication Netherlands ISSN/ISBN 1879-3460; 0168-1605 Accession Number PMID: 20167386 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.ijfoodmicro.2010.01.024 [doi] Output Language Unknown(0) PMID 20167386 Abstract Plaa-som is a Thai fermented fish product for which whole fish or fish fillets are fermented with either cooked rice or steamed sticky rice, salt, and garlic. A total of 762 lactic acid bacteria (LAB) were isolated during plaa-som fermentation by culture on CaCO(3)-MRS agar plates. They were screened and grouped by amplified ribosomal DNA restriction analysis (ARDRA), giving six groups that were identified by ribosomal DNA sequencing as Lactococcus garvieae, Streptococcus bovis, Weissella cibaria, Pediococcus pentosaceus, Lactobacillus plantarum, and Lactobacillus fermentum. Freshly mixed ingredients contained low populations of LAB (less than 10 CFU/g) that subsequently grew during fermentation to final populations of approximately 10(7)CFU/g. Early stages of the process were dominated by the presence of Lc. garvieae, S. bovis, and W. cibaria. At 48 h into fermentation, W. cibaria, P. pentosaceus, and Lb. plantarum were prevalent, and gave way to a dominance of Lb. plantarum that completed the fermentation. A mixture of these LAB species could be considered as species for development of a starter culture for plaa-som fermentation. Descriptors Base Sequence, Colony Count, Microbial, DNA, Bacterial/isolation & purification, DNA, Ribosomal/analysis, Fermentation, Fish Products/microbiology, Food Microbiology, Lactobacillaceae/genetics/growth & development/isolation & purification, RNA, Ribosomal, 16S/analysis, Thailand Links Book Title Database Publisher Elsevier B.V Data Source Authors Kopermsub,P., Yunchalard,S. Original/Translated Title URL Date of Electronic 20100128 PMCID Editors
Highly sensitive determination of polycyclic aromatic hydrocarbons in ambient air dust by gas chromatography-mass spectrometry after molecularly imprinted polymer extraction	2010	National Environmental Engineering Research Institute, Nehru Marg, Nagpur 440 020, India. rj_krupadam@neeri.res.in	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Analytical and bioanalytical chemistry Periodical, Abbrev. Anal.Bioanal Chem. Pub Date Free Form Aug Volume 397 Issue 7 Start Page 3097 Other Pages 3106 Notes LR: 20160512; JID: 101134327; 0 (Air Pollutants); 0 (Dust); 0 (Methacrylates); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Polymers); 0 (Polyvinyls); 0 (poly(vinylpyridine-ethylene dimethacrylate)); 2010/03/05 [received]; 2010/05/18 [accepted]; 2010/05/14 [ Place of Publication Germany ISSN/ISBN 1618-2650; 1618-2642 Accession Number PMID: 20526768 Language eng SubFile Evaluation Studies; Journal Article; IM DOI 10.1007/s00216-010-3858-6 [doi] Output Language Unknown(0) PMID 20526768 Abstract A method based on solid--phase extraction with a molecularly imprinted polymer (MIP) has been developed to determine five probable human carcinogenic polycyclic aromatic hydrocarbons (PAHs) in ambient air dust by gas chromatography-mass spectrometry (GC-MS). Molecularly imprinted poly(vinylpyridine-co-ethylene glycol dimethacrylate) was chosen as solid-phase extraction (SPE) material for PAHs. The conditions affecting extraction efficiency, for example surface properties, concentration of PAHs, and equilibration times were evaluated and optimized. Under optimum conditions, pre-concentration factors for MIP-SPE ranged between 80 and 93 for 10 mL ambient air dust leachate. PAHs recoveries from MIP-SPE after extraction from air dust were between 85% and 97% and calibration graphs of the PAHs showed a good linearity between 10 and 1000 ng L(-1) (r = 0.99). The extraction efficiency of MIP for PAHs was compared with that of commercially available SPE materials--powdered activated carbon (PAC) and polystyrene-divinylbenzene resin (XAD)--and it was shown that the extraction capacity of the MIP was better than that of the other two SPE materials. Organic matter in air dust had no effect on MIP extraction, which produced a clean extract for GC-MS analysis. The detection limit of the method proposed in this article is 0.15 ng L(-1) for benzo[a]pyrene, which is a marker molecule of air pollution. The method has been applied to the determination of probable carcinogenic PAHs in air dust of industrial zones and satisfactory results were obtained. Descriptors Adsorption, Air Pollutants/analysis, Dust/analysis, Gas Chromatography-Mass Spectrometry/methods, Limit of Detection, Methacrylates/chemistry, Molecular Imprinting, Polycyclic Hydrocarbons, Aromatic/analysis/isolation & purification, Polymers/chemistry, Polyvinyls/chemistry, Solid Phase Extraction/instrumentation/methods Links Book Title Database Publisher Data Source Authors Krupadam,R. J., Bhagat,B., Khan,M. S. Original/Translated Title URL Date of Electronic 20100606 PMCID Editors
11-[(E)-Benzyl-idene]-14-hy-droxy-8-phenyl-3,13-diaza-hepta-cyclo-[13.7.1.1.0.0.0 .0]tetra-cosa-1(22),15,17,19(23),20-pentaen-10-one	2010		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Acta crystallographica.Section E, Structure reports online Periodical, Abbrev. Acta Crystallogr.Sect.E.Struct.Rep.Online Pub Date Free Form 6-Nov Volume 66 Issue Pt 12 Start Page o3045 Other Pages Notes LR: 20111209; JID: 101089178; OID: NLM: PMC3011470; 2010/10/22 [received]; 2010/10/27 [accepted]; 2010/11/06 [epublish]; epublish Place of Publication England ISSN/ISBN 1600-5368; 1600-5368 Accession Number PMID: 21589358 Language eng SubFile Journal Article DOI 10.1107/S1600536810043874 [doi] Output Language Unknown(0) PMID 21589358 Abstract In the title compound, C(35)H(30)N(2)O(2), the piperidine ring adopts a chair conformation and the pyrrolidine ring adopts an envelope conformation. The naphthalene ring makes dihedral angles of 24.56 (3) and 36.13 (4) degrees with the terminal phenyl rings. The dihedral angle between the two terminal phenyl rings is 55.27 (5) degrees . One of the C atoms in the pyrrolidine ring is disordered over two sites, with a refined occupany ratio of 0.670 (3):0.330 (3). An intra-molecular O-Hcdots, three dots, centeredN hydrogen bond generates an S(6) ring. In the crystal structure, inversion dimers linked by pairs of C-Hcdots, three dots, centeredO hydrogen bonds generate R(2) (2)(18) loops within sheets of mol-ecules lying parallel to the bc plane. Descriptors Links Book Title Database Publisher Data Source Authors Kumar,R. S., Osman,H., Abdul Rahim,A. S., Hemamalini,M., Fun,H. K. Original/Translated Title URL Date of Electronic 20101106 PMCID PMC3011470 Editors
Motivational interviewing for smoking cessation	2010	Professional Development and Quality Assurance, Department of Health, 1/F Main Block, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Rd, Chai Wan, Hong Kong.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Cochrane database of systematic reviews Periodical, Abbrev. Cochrane Database Syst.Rev. Pub Date Free Form 20-Jan Volume (1):CD006936. doi Issue 1 Start Page CD006936 Other Pages Notes LR: 20150520; JID: 100909747; UIN: Cochrane Database Syst Rev. 2015;3:CD006936. PMID: 25726920; RF: 69; epublish Place of Publication England ISSN/ISBN 1469-493X; 1361-6137 Accession Number PMID: 20091612 Language eng SubFile Journal Article; Meta-Analysis; Review; IM DOI 10.1002/14651858.CD006936.pub2 [doi] Output Language Unknown(0) PMID 20091612 Abstract BACKGROUND: Motivational Interviewing (MI) is a directive patient-centred style of counselling, designed to help people to explore and resolve ambivalence about behaviour change. It was developed as a treatment for alcohol abuse, but may help smokers to a make a successful attempt to quit. OBJECTIVES: To determine the effects of motivational interviewing in promoting smoking cessation. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group Specialized Register for studies with terms (motivational OR motivation OR motivating OR motivate OR behavi* OR motivat) and (interview OR session* OR counsel* OR practi) in the title or abstract, or as keywords. Date of the most recent search: April 2009. SELECTION CRITERIA: Randomized controlled trials in which motivational interviewing or its variants were offered to smokers to assist smoking cessation. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate. The main outcome measure was abstinence from smoking after at least six months follow up. We used the most rigorous definition of abstinence in each trial, and biochemically validated rates where available. Subjects lost to follow up were treated as continuing smokers. We performed meta-analysis using a fixed-effect Mantel-Haenszel model. MAIN RESULTS: We identified 14 studies published between 1997 and 2008, involving over 10,000 smokers. Trials were conducted in one to four sessions, with the duration of each session ranging from 15 to 45 minutes. All but two of the trials used supportive telephone contacts, and supplemented the counselling with self-help materials. MI was generally compared with brief advice or usual care in the trials. Interventions were delivered by primary care physicians, hospital clinicians, nurses or counsellors. Our meta-analysis of MI versus brief advice or usual care yielded a modest but significant increase in quitting (RR 1.27; 95% CI 1.14 to 1.42). Subgroup analyses suggested that MI was effective when delivered by primary care physicians (RR 3.49; 95% CI 1.53 to 7.94) and by counsellors (RR 1.27; 95% CI 1.12 to 1.43), and when it was conducted in longer sessions (more than 20 minutes per session) (RR 1.31; 95% CI 1.16 to 1.49). Multiple session treatments may be slightly more effective than single sessions, but both regimens produced positive outcomes. Evidence is unclear at present on the optimal number of follow-up calls.There was variation across the trials in treatment fidelity. All trials used some variant of motivational interviewing.Critical details in how it was modified for the particular study population, the training of therapists and the content of the counselling were sometimes lacking from trial reports. AUTHORS' CONCLUSIONS: Motivational interviewing may assist smokers to quit. However, the results should be interpreted with caution due to variations in study quality, treatment fidelity and the possibility of publication or selective reporting bias. Descriptors* Behavior Therapy/methods, Hotlines, Humans, Motivation, Randomized Controlled Trials as Topic, Smoking/psychology/therapy, Smoking Cessation/psychology Links Book Title Database Publisher Data Source Authors Lai,D. T., Cahill,K., Qin,Y., Tang,J. L. Original/Translated Title URL Date of Electronic 20100120 PMCID Editors
Secondhand smoke exposures in indoor public places in seven Asian countries	2010	Department of Environmental Health, Graduate School of Public Health and Institute of Health and Environment, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Republic of Korea.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of hygiene and environmental health Periodical, Abbrev. Int.J.Hyg.Environ.Health Pub Date Free Form Sep Volume 213 Issue 5 Start Page 348 Other Pages 351 Notes LR: 20140905; CI: Copyright 2010; GR: 5 D43 TW05750/TW/FIC NIH HHS/United States; GR: D43 TW005750/TW/FIC NIH HHS/United States; JID: 100898843; 0 (Tobacco Smoke Pollution); 2010/01/25 [received]; 2010/05/06 [revised]; 2010/05/12 [accepted]; 2010/06/09 [a Place of Publication Germany ISSN/ISBN 1618-131X; 1438-4639 Accession Number PMID: 20542729 Language eng SubFile Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.ijheh.2010.05.007 [doi] Output Language Unknown(0) PMID 20542729 Abstract Exposure to secondhand smoke (SHS) is a major threat to public health. Asian countries having the highest smoking prevalence are seriously affected by SHS. The objective of the study was to measure SHS levels in hospitality venues in seven Asian countries and to compare the SHS exposure to the levels in Western countries. The study was carried out in four types of related hospitality venues (restaurant, cafe, bar/club and entertainment) in China, India, Japan, Korea, Malaysia, Pakistan and Sri Lanka. Real-time measurement of particulate matter of <2.5microm aerodynamic diameter (PM(2.5)) was made during business hour using a handheld laser operated monitor. A total of 168 venues were measured in seven countries. The average indoor PM(2.5) level was 137microg/m(3), ranging from 46microg/m(3) in Malaysia to 207microg/m(3) in India. Bar/club had the highest PM(2.5) level of 191microg/m(3) and restaurants had the lowest PM(2.5) level of 92microg/m(3). The average indoor PM(2.5) level in smoking venues was 156micro/m(3), which was 3.6 times higher than non-smoking venues (43microg/m(3)). Indoor PM(2.5) levels were significantly associated with country, type of venue, smoking density and air exchange rate (p<0.05). In the seven Asian countries, PM(2.5) levels were high due to SHS in public places. The current levels are comparable to the levels in Western countries before the adoption of smoke-free policy. Since Asian country has high prevalence of SHS in public places, there is an urgent need for comprehensive smoke-free regulation in Asian countries. Descriptors Air Pollution, Indoor/analysis/statistics & numerical data, Asia, Cross-Sectional Studies, Humans, Inhalation Exposure, Restaurants/statistics & numerical data, Tobacco Smoke Pollution/analysis/statistics & numerical data Links Book Title Database Publisher Elsevier GmbH Data Source Authors Lee,J., Lim,S., Lee,K., Guo,X., Kamath,R., Yamato,H., Abas,A. L., Nandasena,S., Nafees,A. A., Sathiakumar,N. Original/Translated Title URL Date of Electronic 20100609 PMCID Editors
Air quality in and around airport enclosed smoking rooms	2010	Graduate School of Public Health, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Periodical, Abbrev. Nicotine Tob.Res. Pub Date Free Form Jun Volume 12 Issue 6 Start Page 665 Other Pages 668 Notes JID: 9815751; 0 (Tobacco Smoke Pollution); 2010/04/21 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 1469-994X; 1462-2203 Accession Number PMID: 20410143 Language eng SubFile Journal Article; IM DOI 10.1093/ntr/ntq054 [doi] Output Language Unknown(0) PMID 20410143 Abstract INTRODUCTION: Smoking rooms have been installed in some airports to allow indoor smoking. There have been few field studies to measure fine particle leakage in operational smoking rooms. The objective of the research was to assess air quality inside and outside the 4 smoking rooms located within a medium-sized, regional commercial airport. METHODS: Particulate matter less than 2.5-microm (PM(2.5)) concentrations were simultaneously measured inside and outside the 4 smoking rooms in the airport and in the public lobby. The monitoring was conducted during normal hours of operation. Numbers of people and smokers were counted. The airport had separate ventilation systems for all 4 rooms checked by the airport prior to monitoring, and they were operating properly. RESULTS: Although there were few smokers in each room, average PM(2.5) concentrations inside the smoking rooms were significantly higher than the National Ambient Air Quality Standard for 24 hr (35 microg/m(3)). Fine particles from secondhand smoke (SHS) leaked to the outside in 3 of the 4 smoking rooms, exposing workers and the public. DISCUSSION: Although the ventilation systems in the smoking rooms were operating properly, fine particles from SHS leaked to the surrounding smoke-free areas in the airport. Indoor space inside airports should be completely nonsmoking, and enclosed smoking rooms are not recommended. Descriptors Air Pollution, Indoor/analysis, Environmental Monitoring, Public Facilities, Tobacco Smoke Pollution/analysis Links Book Title Database Publisher Data Source Authors Lee,K., Hahn,E. J., Robertson,H. E., Whitten,L., Jones,L. K., Zahn,B. Original/Translated Title URL Date of Electronic 20100421 PMCID Editors
Interobserver reliability in the endoscopic diagnosis and grading of Barrett's esophagus: an Asian multinational study	2010	Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Endoscopy Periodical, Abbrev. Endoscopy Pub Date Free Form Sep Volume 42 Issue 9 Start Page 699 Other Pages 704 Notes LR: 20150325; CI: Copyright Georg Thieme Verlag KG Stuttgart . New York.; GR: ZIA CP010136-15/Intramural NIH HHS/United States; JID: 0215166; NIHMS256200; OID: NLM: NIHMS256200; OID: NLM: PMC3000217; 2010/08/30 [epublish]; ppublish Place of Publication Germany ISSN/ISBN 1438-8812; 0013-726X Accession Number PMID: 20806154 Language eng SubFile Journal Article; Multicenter Study; IM DOI 10.1055/s-0030-1255629 [doi] Output Language Unknown(0) PMID 20806154 Abstract BACKGROUND AND STUDY AIM: The establishment of precise and valid diagnostic criteria is important for any disease. We determined the interobserver reliability in the endoscopic diagnosis and grading of Barrett's esophagus. PATIENTS AND METHODS: Video clips of endoscopy in 21 patients with/without Barrett's esophagus were used for training (n = 3) and for diagnosis/grading (n = 18) of Barrett's esophagus by endoscopists from seven hospitals in Asia. Barrett's esophagus was graded using the Prague C & M Criteria whereby the circumferential extent of the Barrett's segment (C value), maximum extent of Barrett's segment (M value), location of the gastroesophageal junction, and location of the diaphragmatic hiatus were scored. The intraclass correlation coefficients (ICC) were calculated as a measure of interobserver reliability. RESULTS: A total of 34 endoscopists participated. ICC values for the scores of the C value, M value, location of the gastroesophageal junction, and location of the diaphragmatic hiatus were: 0.92 (95 % confidence interval [CI] 0.88 - 0.97), 0.94 (95 %CI 0.90 - 0.98), 0.86 (95 %CI 0.78 - 0.94), and 0.81 (95 %CI 0.71 - 0.92), respectively, indicating excellent interobserver agreement. The differences in region/country, endoscopists' experience, case volume of participating centers, or primary practice type had no significant effect on the reliability. The ICC values for recognition of Barrett's esophagus of > or = 1 cm were 0.90 (95 %CI 0.80 - 1.00) and 0.92 (95 %CI 0.87 - 0.98) for the C and M values, respectively, whereas the corresponding ICC values for Barrett's segment of < 1 cm were 0.18 (95 %CI 0.03 - 0.32) and 0.21 (95 %CI 0.00 - 0.51), respectively. CONCLUSIONS: Despite the uncommon occurrence of Barrett's esophagus in Asia, our endoscopists exhibited excellent agreement in the endoscopic diagnosis and grading of Barrett's esophagus using the Prague C & M Criteria. However, in view of the low interobserver reliability in recognizing Barrett's segments of < 1 cm, future studies in Asia should take this into account when selecting the study population. Descriptors Asia, Barrett Esophagus/diagnosis/pathology, Clinical Competence/statistics & numerical data, Esophagoscopy/standards, Humans, Observer Variation, Reproducibility of Results Links Book Title Database Publisher Data Source Authors Lee,Y. C., Cook,M. B., Bhatia,S., Chow,W. H., El-Omar,E. M., Goto,H., Lin,J. T., Li,Y. Q., Rhee,P. L., Sharma,P., Sung,J. J., Wong,J. Y., Wu,J. C., Ho,K. Y., Asian Barrett's Consortium Original/Translated Title URL Date of Electronic 20100830 PMCID PMC3000217 Editors
Low toxic dispersive liquid-liquid microextraction using halosolvents for extraction of polycyclic aromatic hydrocarbons in water samples	2010	Department of Chemistry, National Tsing Hua University, Sec. 2, Kung Fu Rd., 101, Hsinchu, Taiwan.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of chromatography.A Periodical, Abbrev. J.Chromatogr.A Pub Date Free Form 20-Aug Volume 1217 Issue 34 Start Page 5455 Other Pages 5461 Notes LR: 20151119; CI: Copyright 2010; JID: 9318488; 0 (Hydrocarbons, Brominated); 0 (Hydrocarbons, Chlorinated); 0 (Hydroxides); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Potassium Compounds); 0 (Propionates); 0 (Water Pollutants, Chemical); 451W47IQ8X (Sodiu Place of Publication Netherlands ISSN/ISBN 1873-3778; 0021-9673 Accession Number PMID: 20663510 Language eng SubFile Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1016/j.chroma.2010.06.056 [doi] Output Language Unknown(0) PMID 20663510 Abstract A low toxic dispersive liquid-liquid microextraction (LT-DLLME) combined with gas chromatography-mass spectrometry (GC-MS) had been developed for the extraction and determination of 16 polycyclic aromatic hydrocarbons (PAHs) in water samples. In normal DLLME assay, chlorosolvent had been widely used as extraction solvents; however, these solvents are environmental-unfriendly. In order to solve this problem, we proposed to use low toxic bromosolvent (1-bromo-3-methylbutane, LD(50) 6150mg/kg) as the extraction solvent. In this study we compared the extraction efficiency of five chlorosolvents and thirteen bromo/iodo solvents. The results indicated that some of the bromo/iodo solvents showed better extraction and had much lower toxicity than chlorosolvents. We also found that propionic acid is used as the disperser solvent, as little as 50microL is effective. Under optimum conditions, the range of enrichment factors and extraction recoveries of tap water samples are ranging 372-1308 and 87-105%, respectively. The linear range is wide (0.01-10.00microgL(-1)), and the limits of detection are between 0.0003 and 0.0078microgL(-1) for most of the analytes. The relative standard deviations (RSD) for 0.01microgL(-1) of PAHs in tap water were in the range of 5.1-10.0%. The performance of the method was gauged by analyzing samples of tap water, sea water and lake water samples. Descriptors Chemical Fractionation/methods, Fresh Water/chemistry, Gas Chromatography-Mass Spectrometry, Hydrocarbons, Brominated/chemistry, Hydrocarbons, Chlorinated/chemistry, Hydroxides/chemistry, Polycyclic Hydrocarbons, Aromatic/analysis/isolation & purification, Potassium Compounds/chemistry, Propionates/chemistry, Sodium Chloride/chemistry, Water Pollutants, Chemical/analysis/isolation & purification Links Book Title Database Publisher Elsevier B.V Data Source Authors Leong,M. I., Chang,C. C., Fuh,M. R., Huang,S. D. Original/Translated Title URL Date of Electronic 20100630 PMCID Editors

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