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Effect of glycemic control on self-perceived oral health, periodontal parameters, and alveolar bone loss among patients with prediabetes 2014 Eng. A.B. Research Chair for Growth Factors and Bone Regeneration, Three-Dimensional Imaging and Biomechanical Laboratory, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
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Journal Article
Periodical, Full
Journal of periodontology
Periodical, Abbrev.
J.Periodontol.
Pub Date Free Form
Feb
Volume
85
Issue
2
Start Page
234
Other Pages
241
Notes
JID: 8000345; 0 (Blood Glucose); 0 (Hemoglobin A, Glycosylated); 2013/05/09 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1943-3670; 0022-3492
Accession Number
PMID: 23659422
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; D; IM
DOI
10.1902/jop.2013.130008 [doi]
Output Language
Unknown(0)
PMID
23659422
Abstract
BACKGROUND: The effect of glycemic control on severity of periodontal inflammatory parameters in patients with prediabetes is unknown. The aim of the present study is to assess the effects of glycemic control on self-perceived oral health, periodontal parameters, and marginal bone loss (MBL) in patients with prediabetes. METHODS: A total of 303 individuals were included. Hemoglobin A1c (HbA1c) and fasting blood glucose levels (FBGLs) were recorded. Participants were divided into three groups: 1) group A: 75 patients with prediabetes (FBGLs = 100 to 125 mg/dL [HbA1c >/=5%]); 2) group B: 78 individuals previously considered prediabetic but having FBGLs
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Javed,F., Thafeed Alghamdi,A.S., Mikami,T., Mehmood,A., Ahmed,H.B., Samaranayake,L.P., Tenenbaum,H.C.
Original/Translated Title
URL
Date of Electronic
20130509
PMCID
Editors
Effect of heat processing and storage time on migration of bisphenol A (BPA) and bisphenol A-diglycidyl ether (BADGE) to aqueous food simulant from Mexican can coatings 2001 Centro de Investigacion en Alimentacion y Desarrollo, A.C. Apartado Postal 1735, Hermosillo, Sonora 83000, Mexico.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of Agricultural and Food Chemistry
Periodical, Abbrev.
J.Agric.Food Chem.
Pub Date Free Form
Aug
Volume
49
Issue
8
Start Page
3666
Other Pages
3671
Notes
LR: 20131121; JID: 0374755; 0 (Benzhydryl Compounds); 0 (Carcinogens); 0 (Epoxy Compounds); 0 (Phenols); F3XRM1NX4H (2,2-bis(4-glycidyloxyphenyl)propane); MLT3645I99 (bisphenol A); ppublish
Place of Publication
United States
ISSN/ISBN
0021-8561; 0021-8561
Accession Number
PMID: 11513645
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
jf0009044 [pii]
Output Language
Unknown(0)
PMID
11513645
Abstract
Effects of heat processing and storage time (up to 70 days) on migration of bisphenol A (BPA) and bisphenol A-diglycidyl ether (BADGE) from can coatings into an aqueous food simulant were determined. Distilled water was canned in two types of Mexican cans: for tuna and for jalapeno peppers. Results showed that there is an effect of heat treatment on migration of both compounds. Storage time did not show any effect in BPA migration from tuna cans. There was an effect of storage time on BPA migration from jalapeno pepper cans. Results for BADGE migration were affected by its susceptibility to hydrolyze in aqueous simulants. BADGE concentration decreased, or was not detected, during storage in both types of cans. Migration levels for BPA and BADGE were within 0.6-83.4 and <0.25-4.3 microg/kg, respectively. Both were below European and Mercosur legislation limits. Other migrating compounds were detected, although no identification was performed.
Descriptors
Benzhydryl Compounds, Carcinogens/analysis, Epoxy Compounds/analysis, Food Contamination, Food Handling/methods, Food Packaging, Food Preservation, Hot Temperature/adverse effects, Humans, Phenols/analysis, Time Factors
Links
Book Title
Database
Publisher
Data Source
Authors
Munguia-Lopez,E. M., Soto-Valdez,H.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Effect of heavy metals and benzene on porphyrin synthesis of human epithelial larynx carcinoma cells (HEp-2) 2001 Herbarth, O., UFZ - Umweltforsch. Ztrm. L.-H. GmbH, Sekt. Expositionsforsch./Epidemiol., Medizinische Fak. der Univ. Leipzig, D-04318 Leipzig, Germany
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Print(0)
Ref Type
Journal Article
Periodical, Full
Umweltmedizin in Forschung und Praxis
Periodical, Abbrev.
Umweltmed.Forsch.Prax.
Pub Date Free Form
2001/
Volume
6
Issue
4
Start Page
221
Other Pages
230
Notes
Place of Publication
ISSN/ISBN
1430-8681
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Aim of the investigation was to prepare an environmental epidemiological test to detect the effects of pollutants by a pattern of porphyrin excretion in the urine. The task was to test whether lead, mercury, copper, zinc and benzene in environmentally relevant concentrations influence porphyrin synthesis of cells. The model used was the permanent epithelial larynx carcinoma cell line HEp-2, which was stimulated to synthesize porphyrins by adding δ-amino-levulinic acid (δ-ALA) in excess. 8- to 4-carboxyporphyrins and protoporphyrin IX were measured both in the cells and in the culture medium by means of high performance liquid cromatography (HPLC). The following pollutant effects were found: lead: extracellular increase of hexacarboxyporphyrin and intracellular decrease of heptacarboxy- and copro-porphyrin; mercury: extracellular decrease of heptacarboxyporphyrin and intracellular increase of coproporphyrin; copper: extracellular decrease of uro-, coproporphyrin and protoporphyrin IX, extracellular increase of heptacarboxyporphyrin and intracellular decrease of uro-, heptacarboxy- and coproporphyrin; zinc: extracellular increase of coproporphyrin; benzene: a tendency to extracellular increase of hexacarboxyporphyrin. The main result is the decrease in the concentrations of porphyrins caused by copper. This result is possibly linked to gastro-intestinal diseases among children due to drinking water from copper water pipes.
Descriptors
aminolevulinic acid, benzene, copper, heavy metal, lead, mercury, porphyrin, protoporphyrin, zinc, article, carcinoma cell, cell culture, culture medium, drinking, gastrointestinal disease, heme synthesis, high performance liquid chromatography, human, larynx carcinoma, pollutant, urinary excretion, water contamination
Links
Book Title
Wirkung von schwermetallen und benzol auf die porphyrinsynthese von humanen epithelialen larynxkarzinomzellen (HEp-2)
Database
Embase
Publisher
Data Source
Embase
Authors
Tumat,C., Kath,H. -G, Perlewitz,J., Herbarth,O., Manuwald,O.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Effect of in-office bleaching agents on the color changes of stained ceromers and direct composite resins 2014 The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University , Wuhan , PR China.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta Odontologica Scandinavica
Periodical, Abbrev.
Acta Odontol.Scand.
Pub Date Free Form
Nov
Volume
72
Issue
8
Start Page
1032
Other Pages
1038
Notes
JID: 0370344; 0 (Coffee); 0 (Composite Resins); 0 (Dental Materials); 0 (Drug Combinations); 0 (Gradia); 0 (Peroxides); 0 (Polyvinyls); 0 (Silicates); 0 (Tea); 0 (Tooth Bleaching Agents); 0 (ceramage); 0 (ceromer); 0 (tooth-bleaching agent, Opalescence);
Place of Publication
England
ISSN/ISBN
1502-3850; 0001-6357
Accession Number
PMID: 25196263
Language
eng
SubFile
Comparative Study; Journal Article; D; IM
DOI
10.3109/00016357.2014.946962 [doi]
Output Language
Unknown(0)
PMID
25196263
Abstract
PURPOSE: To evaluate the effect of two in-office bleaching agents on the color changes of two ceromers (Ceramage and Adoro SR) and one direct composite resin (Gradia Direct Anterior) after staining by tea and coffee. MATERIALS AND METHODS: Twenty-four disk-shaped specimens were fabricated for each resin material and randomly divided into three groups (n = 8). The specimens were immersed in tea, coffee or deionized water, respectively, for 7 days. Each group was then equally divided into two sub-groups (n = 4), which were subjected to two in-office bleaching agents (BEYOND and Opalescence Boost), respectively. The color of the specimens was measured by a spectrophotometer at baseline, after staining and after bleaching. The color differences (DeltaE values) between baseline and after treatments were calculated. RESULTS: Statistical analysis indicated that the staining solution had significant influence on the color change of resin composites tested (p 2.0). There was no statistically significant difference between BEYOND and Opalescence Boost in stains removal from discolored resins (p = 0.550). The color changes in DeltaE value between baseline and after bleaching were less than 2.0 for all resin composite groups. CONCLUSIONS: Tea solution produces severe discoloration of three resin composites tested. The two in-office bleaching agents can effectively remove the stains from two ceromers and one direct composite resin tested in this study.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Xing,W., Jiang,T., Liang,S., Sa,Y., Wang,Z., Chen,X., Wang,Y.
Original/Translated Title
URL
Date of Electronic
20140908
PMCID
Editors
Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation 2010 Department of Basic and Applied Medical Sciences, Ud'A Chieti-Pescara, Italy.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of applied physiology (Bethesda, Md.: 1985)
Periodical, Abbrev.
J.Appl.Physiol.(1985)
Pub Date Free Form
May
Volume
108
Issue
5
Start Page
1077
Other Pages
1083
Notes
LR: 20131121; JID: 8502536; 0 (ITGB3 protein, human); 0 (Integrin beta3); 0 (P-Selectin); 0 (Platelet Membrane Glycoprotein IIb); S88TT14065 (Oxygen); 2010/02/25 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
1522-1601; 0161-7567
Accession Number
PMID: 20185629
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1152/japplphysiol.01058.2009 [doi]
Output Language
Unknown(0)
PMID
20185629
Abstract
Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation in scuba divers was evaluated. Six volunteers participated in four diving protocols, with 2 wk of recovery between dives. On dive 1, before diving, all divers breathed normally for 20 min at the surface of the sea (Air). On dive 2, before diving, all divers breathed 100% oxygen for 20 min at the surface of the sea [normobaric oxygenation (NBO)]. On dive 3, before diving, all divers breathed 100% O2 for 20 min at 6 m of seawater [msw; hyperbaric oxygenation (HBO) 1.6 atmospheres absolute (ATA)]. On dive 4, before diving, all divers breathed 100% O2 for 20 min at 12 msw (HBO 2.2 ATA). Then they dove to 30 msw (4 ATA) for 20 min breathing air from scuba. After each dive, blood samples were collected as soon as the divers surfaced. Bubbles were measured at 20 and 50 min after decompression and converted to bubble count estimate (BCE) and numeric bubble grade (NBG). BCE and NBG were significantly lower in NBO than in Air [0.142+/-0.034 vs. 0.191+/-0.066 (P<0.05) and 1.61+/-0.25 vs. 1.89+/-0.31 (P<0.05), respectively] at 20 min, but not at 50 min. HBO at 1.6 ATA and 2.2 ATA has a similar significant effect of reducing BCE and NBG. BCE was 0.067+/-0.026 and 0.040+/-0.018 at 20 min and 0.030+/-0.022 and 0.020+/-0.020 at 50 min. NBG was 1.11+/-0.17 and 0.92+/-0.16 at 20 min and 0.83+/-0.18 and 0.75+/-0.16 at 50 min. Prebreathing NBO and HBO significantly alleviated decompression-induced platelet activation. Activation of CD62p was 3.0+/-0.4, 13.5+/-1.3, 10.7+/-0.9, 4.5+/-0.7, and 7.6+/-0.8% for baseline, Air, NBO, HBO at 1.6 ATA, and HBO at 2.2 ATA, respectively. The data show that prebreathing oxygen, more effective with HBO than NBO, decreases air bubbles and platelet activation and, therefore, may be beneficial in reducing the development of decompression sickness.
Descriptors
Administration, Inhalation, Adult, Decompression/adverse effects, Decompression Sickness/blood/physiopathology/prevention & control/ultrasonography, Diving, Embolism, Air/blood/physiopathology/prevention & control/ultrasonography, Humans, Hyperbaric Oxygenation, Immersion, Inhalation, Integrin beta3/blood, Male, Middle Aged, Oxygen/administration & dosage, P-Selectin/blood, Platelet Activation, Platelet Membrane Glycoprotein IIb/blood, Time Factors, Ultrasonography, Doppler, Young Adult
Links
Book Title
Database
Publisher
Data Source
Authors
Bosco,G., Yang,Z. J., Di Tano,G., Camporesi,E. M., Faralli,F., Savini,F., Landolfi,A., Doria,C., Fano,G.
Original/Translated Title
URL
Date of Electronic
20100225
PMCID
Editors
Effect of in-water recompression with oxygen to 6 msw versus normobaric oxygen breathing on bubble formation in divers 2009 Ecole de Plongee Marine Nationale, 83800 Toulon Armees, France. je.blatteau@infonie.fr
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
European journal of applied physiology
Periodical, Abbrev.
Eur.J.Appl.Physiol.
Pub Date Free Form
Jul
Volume
106
Issue
5
Start Page
691
Other Pages
695
Notes
LR: 20131121; JID: 100954790; 059QF0KO0R (Water); S88TT14065 (Oxygen); 2009/04/15 [accepted]; 2009/05/08 [aheadofprint]; ppublish
Place of Publication
Germany
ISSN/ISBN
1439-6327; 1439-6319
Accession Number
PMID: 19424716
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; IM
DOI
10.1007/s00421-009-1065-y [doi]
Output Language
Unknown(0)
PMID
19424716
Abstract
It is generally accepted that the incidence of decompression sickness (DCS) from hyperbaric exposures is low when few or no bubbles are present in the circulation. To date, no data are available on the influence of in-water oxygen breathing on bubble formation following a provocative dive in man. The purpose of this study was to compare the effect of post-dive hyperbaric versus normobaric oxygen breathing (NOB) on venous circulating bubbles. Nineteen divers carried out open-sea field air dives at 30 msw depth for 30 min followed by a 9 min stop at 3 msw. Each diver performed three dives: one control dive, and two dives followed by 30 min of hyperbaric oxygen breathing (HOB) or NOB; both HOB and NOB started 10 min after surfacing. For HOB, divers were recompressed in-water to 6 msw at rest, whereas NOB was performed in a dry room in supine position. Decompression bubbles were examined by a precordial pulsed Doppler. Bubble count was significantly lower for post-dive NOB than for control dives. HOB dramatically suppressed circulating bubble formation with a bubble count significantly lower than for NOB or controls. In-water recompression with oxygen to 6 msw is more effective in removing gas bubbles than NOB. This treatment could be used in situations of "interrupted" or "omitted" decompression, where a diver returns to the water in order to complete decompression prior to the onset of symptoms. Further investigations are needed before to recommend this protocol as an emergency treatment for DCS.
Descriptors
Adult, Decompression/adverse effects, Decompression Sickness/physiopathology/prevention & control, Diving/physiology, Embolism, Air/prevention & control, Humans, Hyperbaric Oxygenation/methods, Immersion, Male, Middle Aged, Osmolar Concentration, Oxygen/pharmacology/therapeutic use, Oxygen Consumption/physiology, Respiration, Water, Young Adult
Links
Book Title
Database
Publisher
Data Source
Authors
Blatteau,J. E., Pontier,J. M.
Original/Translated Title
URL
Date of Electronic
20090508
PMCID
Editors
Effect of light-cured filled sealant on shear bond strength of metal and ceramic brackets bonded with a resin-modified glass ionomer cement 2009 Department of Orthodontics, Faculty of Dentistry, Gazi University, Ankara, Turkey. kaleselin@yahoo.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, its Constituent Societies, and the American Board of Orthodontics
Periodical, Abbrev.
Am.J.Orthod.Dentofacial Orthop.
Pub Date Free Form
Feb
Volume
135
Issue
2
Start Page
194
Other Pages
198
Notes
LR: 20151119; JID: 8610224; 0 (Acrylic Resins); 0 (Aluminum Silicates); 0 (Dental Alloys); 0 (Fuji Ortho LC); 0 (Glass Ionomer Cements); 0 (Phosphoric Acids); 0 (Pro Seal); 0 (Resin Cements); 059QF0KO0R (Water); E4GA8884NN (phosphoric acid); 2007/08/01 [r
Place of Publication
United States
ISSN/ISBN
1097-6752; 0889-5406
Accession Number
PMID: 19201326
Language
eng
SubFile
Comparative Study; Journal Article; Randomized Controlled Trial; D; IM
DOI
10.1016/j.ajodo.2007.12.024 [doi]
Output Language
Unknown(0)
PMID
19201326
Abstract
INTRODUCTION: Our objective was to evaluate the effects of a highly filled light-cured sealant (HFLCS) on the shear bond strength and bond failure site of metal and ceramic brackets bonded with resin-modified glass ionomer cement (RMGIC). METHODS: Eighty freshly extracted maxillary premolars were randomly divided into 4 groups (20 in each group). In all groups, the teeth were etched with 37% phosphoric acid for 20 seconds, and RMGIC (Fuji Ortho LC, GC Europe, Leuven, Belgium) was used for bracket bonding. In groups 1 and 3, the brackets were bonded directly to etched enamel surfaces; in groups 2 and 4, the etched enamel was covered with HFLCS (Pro Seal, Reliance Orthodontic Products, Itasca, Ill). Groups 1 and 2 received metal brackets, and groups 3 and 4 had ceramic brackets. The specimens were stored in distilled water at room temperature for 24 hours and subsequently tested in shear mode with a universal testing machine. After debonding, the teeth and the brackets were examined under a stereomicroscope (model SMZ-1B, Nikon, Osaka, Japan) at 20-times magnification to assess the residual adhesive on the tooth surfaces. RESULTS: Interaction between HFLCS and bracket type was not statistically significant (P = 0.15). Pretreatment with HFLCS did not cause a statistically significant change in the shear bond values of either metal or ceramic brackets (P = 0.38). Shear bond values of the ceramic brackets were higher than those of the metal brackets independent of HFLCS application (P <0.001). No significant differences were found in bond failure modes in the 4 groups. CONCLUSIONS: HFLCS application on enamel etched with 37% phosphoric acid did not affect the bond strength values and the bond failure modes of metal and ceramic brackets bonded with RMGIC. RESULTS: Interaction between HFLCS and bracket type was not statistically significant (P = 0.15). Pretreatment with HFLCS did not cause a statistically significant change in the shear bond values of either metal or ceramic brackets (P = 0.38). Shear bond values of the ceramic brackets were higher than those of the metal brackets independent of HFLCS application (P <0.001). No significant differences were found in bond failure modes in the 4 groups. CONCLUSIONS: HFLCS application on enamel etched with 37% phosphoric acid did not affect the bond strength values and the bond failure modes of metal and ceramic brackets bonded with RMGIC.
Descriptors
Acid Etching, Dental, Acrylic Resins/chemistry, Aluminum Silicates/chemistry, Ceramics/chemistry, Dental Alloys/chemistry, Dental Enamel/pathology, Glass Ionomer Cements/chemistry, Humans, Light-Curing of Dental Adhesives, Materials Testing, Orthodontic Appliance Design, Orthodontic Brackets, Phosphoric Acids/chemistry, Resin Cements/chemistry, Shear Strength, Stress, Mechanical, Surface Properties, Temperature, Time Factors, Water/chemistry
Links
Book Title
Database
Publisher
Data Source
Authors
Varlik,S. K., Ulusoy,C.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Effect of low-intensity continuous training on lung function and cardiorespiratory fitness in both cigarette and hookah smokers 2015 Laboratory of Pharmacology, Sfax Medicine Faculty SMF, University of Sfax, Tunisia; Bizerte Sciences Faculty, Department of Biology, University of Carthage. Tunisia; Research Unit (EM2S), Higher Institute of Sport and Physical Education of Sfax, Universit
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
African health sciences
Periodical, Abbrev.
Afr.Health.Sci.
Pub Date Free Form
Dec
Volume
15
Issue
4
Start Page
1170
Other Pages
1181
Notes
LR: 20160311; JID: 101149451; OID: NLM: PMC4765424; OTO: NOTNLM; ppublish
Place of Publication
Uganda
ISSN/ISBN
1729-0503; 1680-6905
Accession Number
PMID: 26958018
Language
eng
SubFile
Journal Article; IM
DOI
10.4314/ahs.v15i4.16 [doi]
Output Language
Unknown(0)
PMID
26958018
Abstract
BACKGROUND: The decline in cardiorespiratory fitness and lung function was higher in smokers. Training method could mitigate some of the negative consequences of smoking among smokers unable or unwilling to quit. OBJECTIVE: To examine the effects of continuous training on lungs functional capability and cardiorespiratory fitness in smokers. METHODS: Fifteen cigarette smokers, 14 hookah smokers, and 14 nonsmokers were assigned to low-intensity continuous training (20-30 minutes of running at 40% of maximum oxygen uptake (O2max)). Lung function and cardiorespiratory fitness parameters were determined using respectively spirometer and treadmill maximal exercise test. RESULTS: Continuous training improved forced expiratory volume in one second (FEV1) and forced expiratory flow at 50% of FVC (FEF50 %) in all participants, smokers and nonsmokers (p
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Koubaa,A., Triki,M., Trabelsi,H., Masmoudi,L., Zeghal,K.N., Sahnoun,Z., Hakim,A.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4765424
Editors
Effect of maternal tobacco smoking or exposure to second-hand smoke on the levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine of mother and the first urine of newborn 2011 Laboratory of Environmental Research, Department of Toxicology, University of Medical Sciences, Poznan, Poland.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Periodical, Abbrev.
J.Physiol.Pharmacol.
Pub Date Free Form
Jun
Volume
62
Issue
3
Start Page
377
Other Pages
383
Notes
LR: 20151119; JID: 9114501; 0 (4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol); 0 (Biomarkers); 0 (Carcinogens); 0 (Nitrosamines); 0 (Pyridines); 0 (Tobacco Smoke Pollution); 6M3C89ZY6R (Nicotine); AYI8EX34EU (Creatinine); K5161X06LL (Cotinine); 2011/04
Place of Publication
Poland
ISSN/ISBN
1899-1505; 0867-5910
Accession Number
PMID: 21893699
Language
eng
SubFile
Journal Article; IM
DOI
Output Language
Unknown(0)
PMID
21893699
Abstract
Tobacco smoking during pregnancy is associated with a variety of negative consequences not only for the mother, but also for the developing fetus. Many studies have shown that carcinogens contained in tobacco smoke permeate across the placenta, and are found in fetus. The aim of the study was to determine the prenatal exposure to tobacco-specific carcinogenic N-nitrosamines on the basis of measurements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine of smoking and second-hand smoke (SHS) exposed women and in the first urine of their newborns. A questionnaire documenting demographics and socio-economical data, smoking habits and exposure to SHS was completed by 121 delivering women near or at term. Maternal concentrations of cotinine and NNAL were measured in urine of the mother and the first urine of her newborn infant by liquid chromatography tandem mass spectrometry (LC/MS/MS). The mean concentration of cotinine was 439.2 ng/mg creatinine and NNAL concentration in urine of smoking women was 74.0 pg/mg creatinine, and for her newborn 78.6 pg/mg creatinine. Among mothers exposed to SHS, cotinine and NNAL mean concentration were 23.1 ng/mg creatinine, and 26.4 pg/mg creatinine. In newborns of SHS exposed mothers during pregnancy the mean concentration of NNAL was 34.1 pg/mg creatinine, respectively. Active tobacco smoking as well as passive exposure to smoking during pregnancy is an important source of tobacco specific N-nitrosamines to the fetuses as evidenced by increased concentrations of this carcinogen. Determination of NNAL in maternal urine samples can be a useful biomarker of prenatal exposure of newborn to carcinogenic nitrosamines.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Florek,E., Piekoszewski,W., Basior,A., Merritt,A.T., Mazela,J., Lechowicz,W., Kornacka,M.K., Kramer,L.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
effect of meassel water-pipe smoking versus cigarette smoking on pulmonary arterial pressure and left ventricular and right ventricular function indices in COPD patients, an echodoppler study 2000
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Scientific Journal of Al-Azhar Medical Faculty Girls] The]
Periodical, Abbrev.
Pub Date Free Form
Volume
21
Issue
1
Start Page
649
Other Pages
686
Notes
ID: 63456
Place of Publication
ISSN/ISBN
Accession Number
Language
english
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
This study included 165 COPD heavy smoker patients with a mean age of 59.9 +/- 8.9 year referred for echo Doppler and cardiac assessment. They were divided according to their type of smoked material into three groups; cigarette smoker group, meassel water-pipe smoker group and cigarette and water-pipe smoker group. The aim of the study was to assess the prevalence of echo Doppler abnormalities in those patients looking for any specific pattern induced by meassel. The results have shown that the common effects of the whole smoker groups when compared to the non-smoker group were as follows: Severe reduction in FEV 1/FVC%, arterial pO2 reduction, left ventricular diastolic dysfunction, right ventricular diastolic dysfunction, impaired index of global right ventricular function, decreased pulmonary acceleration time and right ventricular enlargement. However, water-pipe smoker group if compared to cigarette smoker group showed more aggressive pulmonary obstruction, more degree of pulmonary hypertension, more right ventricular enlargement and more deterioration of right ventricular global function index. In conclusion, the hazards of heavy water-pipe meassel smoking on echo Doppler, FEV1/FVC% and arterial blood gases indices are not only similar to those of heavy cigarette smoking but also it cause more respiratory obstruction, more pulmonary hypertension and more deleterious effect on right ventricular size and global function
Descriptors
Humans, Male, Female, Smoking/physiology, Lung Diseases, Obstructive, Pulmonary Heart Disease, Respiratory Function Tests, Blood Gas Analysis, Echocardiography, Pulmonary Emphysema
Links
http://pesquisa.bvsalud.org/ghl/resource/en/emro-63456
Book Title
Database
GHL; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Mazen,Adel Ahmed, Oraby,Sabah Saad
Original/Translated Title
URL
Date of Electronic
PMCID
Editors