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Diethyl 2,6-dihy-droxy-4-(3-nitro-phen-yl)-2,6-bis-(trifluoro-meth-yl)piperidine-3,5-dica rboxyl-ate 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Acta crystallographica.Section E, Structure reports online
Periodical, Abbrev.
Acta Crystallogr.Sect.E.Struct.Rep.Online
Pub Date Free Form
1-Feb
Volume
68
Issue
Pt 2
Start Page
o400
Other Pages
1
Notes
JID: 101089178; OID: NLM: PMC3275076; 2011/12/16 [received]; 2011/12/23 [accepted]; 2012/01/14 [epublish]; ppublish
Place of Publication
United States
ISSN/ISBN
1600-5368; 1600-5368
Accession Number
PMID: 22347021
Language
eng
SubFile
Journal Article
DOI
10.1107/S1600536811055346 [doi]
Output Language
Unknown(0)
PMID
22347021
Abstract
In the title compound, C(19)H(20)F(6)N(2)O(8), the eth-oxy and ethyl groups are disordered over two sets of sites, with occupancy ratios of 0.212 (18):0.788 (18) and 0.746 (6):0.254 (6), respectively. The piperidine ring adopts a chair conformation. In the mol-ecule, intra-molecular O-Hcdots, three dots, centeredO hydrogen bonds form two S(6) ring motifs. In the crystal, mol-ecules are linked via O-Hcdots, three dots, centeredO and C-Hcdots, three dots, centeredO hydrogen bonds, forming dimers.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Fun,H.K., Arshad,S., Reddy,B.P., Vijayakumar,V., Sarveswari,S.
Original/Translated Title
URL
Date of Electronic
20120114
PMCID
PMC3275076
Editors
Differences in bonding to acid-etched or Er:YAG-laser-treated enamel and dentin surfaces 2000 Santiago de Compostela University, Santiago de Compostela, Spain. odamain@uscmail.usc.es
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of prosthetic dentistry
Periodical, Abbrev.
J.Prosthet.Dent.
Pub Date Free Form
Sep
Volume
84
Issue
3
Start Page
280
Other Pages
288
Notes
LR: 20061115; JID: 0376364; 0 (Resin Cements); ppublish
Place of Publication
UNITED STATES
ISSN/ISBN
0022-3913; 0022-3913
Accession Number
PMID: 11005900
Language
eng
SubFile
Comparative Study; Evaluation Studies; Journal Article; D; IM
DOI
S0022-3913(00)78826-3 [pii]
Output Language
Unknown(0)
PMID
11005900
Abstract
STATEMENT OF PROBLEM: Er:YAG (erbium-doped yttrium aluminium garnet) lasers have been effective in the removal of dental tissues. It has been suggested that they are also useful for preparing dental surfaces for adhesion, but results to date have been controversial. PURPOSE: This study compared the tensile strength of bracket-tooth bonds obtained after preparation of the surface for adhesion (dentin or enamel) by conventional acid-etching or by Er:YAG laser etching and investigated microstructure of resin-tooth interfaces using the 2 procedures. MATERIAL AND METHODS: Eighty healthy human premolars were used. Brackets were cemented to acid-etched enamel, laser-etched enamel, acid-etched dentin, or laser-etched dentin (20 teeth per group). Dentin was previously exposed using a high-speed handpiece. Acid-etching was with 37% orthophosphoric acid (15 seconds for enamel, 5 seconds for dentin). Laser etching was with Er:YAG laser (four 200 mJ pulses per second for enamel; four 160 mJ pulses per second for dentin). Brackets were bonded with autocuring resin paste, having first applied a primer (dentin only) and then light-cured bonding resin. Tensile strength was determined with a universal testing machine. Data were analyzed with 2-way ANOVA and subsequent t test with Bonferroni correction. Fracture patterns were compared by the Wilcoxon test with Bonferroni correction. For SEM studies of the resin-tooth interface, a total of 12 premolars were used (3 for each tissue per treatment combination). RESULTS: Mean tensile bond strength for acid-etched enamel (14.05 +/- 5.03 MPa) was significantly higher (P<.05) than for laser-etched enamel (8.45 +/- 3.07 MPa), and significantly higher (P<.05) for acid-etched dentin (4.70 +/- 2.50 MPa) than laser-etched dentin (2.48 +/- 1.94 MPa). Bond failure after laser etching was due to microcohesive fracture of tooth tissue. SEM studies of both resin-enamel and resin-dentin interfaces indicated extensive subsurface fissuring after laser etching. CONCLUSION: Adhesion to dental hard tissues after Er:YAG laser etching is inferior to that obtained after conventional acid etching. Enamel and dentin surfaces prepared by Er:YAG laser etching show extensive subsurface fissuring that is unfavorable to adhesion.
Descriptors
Acid Etching, Dental, Analysis of Variance, Dental Bonding, Dental Enamel/drug effects/radiation effects, Dentin/drug effects/radiation effects, Humans, Lasers, Microscopy, Electron, Scanning, Orthodontic Brackets, Resin Cements, Statistics, Nonparametric, Surface Properties/drug effects/radiation effects, Tensile Strength
Links
Book Title
Database
Publisher
Data Source
Authors
Martinez-Insua,A., Da Silva Dominguez,L., Rivera,F. G., Santana-Penin,U. A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Differences in ERK activation in squamous mucosa in patients who have gastroesophageal reflux disease with and without Barrett&#39;s esophagus 2005 Department of Medicine, Dallas VA Medical Center, University of Texas-Southwestern Medical School, Dallas, Texas, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The American Journal of Gastroenterology
Periodical, Abbrev.
Am.J.Gastroenterol.
Pub Date Free Form
Mar
Volume
100
Issue
3
Start Page
551
Other Pages
559
Notes
LR: 20150923; GR: DK63621/DK/NIDDK NIH HHS/United States; GR: HL61897/HL/NHLBI NIH HHS/United States; GR: HL67256/HL/NHLBI NIH HHS/United States; GR: R01 DK063621/DK/NIDDK NIH HHS/United States; GR: R01 HL061897/HL/NHLBI NIH HHS/United States; GR: R01 HL0
Place of Publication
United States
ISSN/ISBN
0002-9270; 0002-9270
Accession Number
PMID: 15743351
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; IM
DOI
AJG41122 [pii]
Output Language
Unknown(0)
PMID
15743351
Abstract
OBJECTIVES: In some patients with gastroesophageal reflux disease (GERD), the reflux-damaged esophageal squamous epithelium heals through the process of intestinal metaplasia (resulting in Barrett's esophagus) rather than through the regeneration of more squamous cells. We hypothesized that squamous epithelium in Barrett's esophagus might have abnormalities in activation of the extracellular-regulated kinases 1 and 2 (ERK1/2) signaling pathway that may facilitate esophageal repair through metaplasia in response to acid-induced injury. METHODS: Endoscopic biopsies were taken from distal esophageal squamous mucosa in patients who had GERD with and without Barrett's esophagus and in controls, before and after esophageal perfusion with 0.1 N HCl acid. Basal ERK1/2 phosphorylation, acid-induced ERK1/2 activity and phosphorylation, and localization of phosphorylated ERK1/2 were determined using immunoblotting, Western blotting, and immunohistochemistry. RESULTS: Compared to patients with Barrett's esophagus, patients with GERD exhibited significantly lower baseline levels of phosphorylated ERK1/2 expression (35 +/- 4%vs 90 +/- 21% control, p= 0.01) Acid exposure significantly increased ERK1/2 activity (346.6 +/- 51.90 to 446.8 +/- 62.44 RIU, p= 0.02) and phosphorylation (3.55 +/- 1.26 to 4.49 +/- 1.25 [ratio phospho/total ERK], p= 0.01) in the squamous mucosa of GERD patients, but not in those with Barrett's esophagus or in controls. CONCLUSIONS: Between patients with Barrett's esophagus and patients with uncomplicated GERD, there are significant differences in baseline levels and in acid-induced activation of ERK1/2 in esophageal squamous epithelium. To our knowledge, this is the first description of a molecular, phenotypic feature that distinguishes the esophageal squamous mucosa of GERD patients with and without Barrett's esophagus.
Descriptors
Adult, Aged, Barrett Esophagus/complications/enzymology, Biopsy, Blotting, Western, Enzyme Activation, Female, Gastroesophageal Reflux/enzymology, Humans, Immunoblotting, Immunohistochemistry, Male, Metaplasia, Middle Aged, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/metabolism, Mucous Membrane/enzymology, Phosphorylation, Signal Transduction/physiology, Tissue Distribution
Links
Book Title
Database
Publisher
Data Source
Authors
Souza,R. F., Shewmake,K. L., Shen,Y., Ramirez,R. D., Bullock,J. S., Hladik,C. L., Lee,E. L., Terada,L. S., Spechler,S. J.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Differences in health and religious beliefs about tobacco use among waterpipe users in the rural male population of Egypt 2012 Department of Epidemiology, School of Public Health, Loma Linda University, Loma Linda, CA 92354, USA. psingh@llu.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Journal of religion and health
Periodical, Abbrev.
J.Relig.Health.
Pub Date Free Form
Dec
Volume
51
Issue
4
Start Page
1216
Other Pages
1225
Notes
LR: 20151119; GR: R01 TW005944/TW/FIC NIH HHS/United States; GR: R01 TW005964-05/TW/FIC NIH HHS/United States; GR: R01 TW05964-01/TW/FIC NIH HHS/United States; GR: R01TW05944/TW/FIC NIH HHS/United States; GR: R03 TW007345/TW/FIC NIH HHS/United States; GR:
Place of Publication
United States
ISSN/ISBN
1573-6571; 0022-4197
Accession Number
PMID: 21125424
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1007/s10943-010-9431-y [doi]
Output Language
Unknown(0)
PMID
21125424
Abstract
Waterpipe use is a highly prevalent form of tobacco use in the Eastern Mediterranean Region that is rooted in long-held cultural traditions that predate the use of cigarettes and present a particular challenge for tobacco control efforts. We did a stratified sampling of 4,994 Egyptian men from rural households of Egypt in order to conduct an interviewer-administered prevalence survey to identify differences in attitudes and beliefs toward smoking and smoking cessation between waterpipe users, cigarette smokers, mixed users (cigarette + waterpipe), and non-smokers. We found that cigarette smokers, mixed users, and/or non-smokers were (1) two- to ninefold more likely to believe that smoking decreased adult life expectancy and harmed a fetus than waterpipe users, (2) significantly more likely to believe that smoking is a sin ("haram") than were waterpipe users. Among tobacco users, we found that cigarette smokers and/or mixed users were significantly more likely to indicate pre-contemplation, contemplation, or intention to quit tobacco than waterpipe users. Our findings from rural Egyptian men indicate that waterpipe users are distinct from cigarette smokers in their perception that their form of tobacco use is less harmful and/or less subject to religious proscription. These beliefs may explain why waterpipe users seem less inclined to quit their tobacco habit and need to be considered in the design of tobacco cessation and prevention methods in Egypt and the region.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Singh,P.N., Neergaard,J., Job,J.S., El Setouhy,M., Israel,E., Mohammed,M.K., Loffredo,C.A.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC3589589
Editors
Differences in prevalence of tobacco use among Indian urban youth: the role of socioeconomic status 2008 Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA. math0304@umn.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Jan
Volume
10
Issue
1
Start Page
109
Other Pages
116
Notes
LR: 20151119; GR: R01 TW005952/TW/FIC NIH HHS/United States; GR: R01TW05952-01/TW/FIC NIH HHS/United States; JID: 9815751; ppublish
Place of Publication
England
ISSN/ISBN
1462-2203; 1462-2203
Accession Number
PMID: 18188751
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1080/14622200701767779 [doi]
Output Language
Unknown(0)
PMID
18188751
Abstract
This study examined whether the distribution of tobacco use and related psychosocial risk factors among youth in urban India vary by socioeconomic status (SES). Data were derived from a cross-sectional survey of students enrolled in the 6th and 8th grades in 32 schools in Delhi and Chennai (N = 11,642). The survey was conducted in 2004, before the implementation of a program designed to prevent and reduce tobacco use (MYTRI). Mixed-effect regression models were used (a) to determine the prevalence of tobacco use among private (higher SES) and government (lower SES) school students, (b) to investigate whether certain psychosocial factors were associated with increased tobacco use, and (c) to determine how these factors varied by school type. Ever-use of multiple forms of tobacco (e.g., gutkha, bidis, and cigarettes) was more prevalent among government school students than private school students. After adjusting for city, gender, grade, and age, we found the prevalence rate for ever-use of any tobacco product to be 18.9% for government school students, compared with 12.2% for private school students (p<.01). Students in government schools scored lower than private school students on most psychosocial risk factors for tobacco use studied here, indicating higher risk. Government school students scored the lowest for refusal skills, self-efficacy, and reasons not to use tobacco. Social susceptibility to chewing tobacco and social susceptibility to smoking were strong correlates of current tobacco use among government school students. Exposure to tobacco advertising was also a strong correlate of current tobacco use for government school students but not private school students. In two large cities of India, students attending government schools are using many forms of tobacco at higher rates than private school students. The psychosocial risk profile of government school students suggests they are more vulnerable to initiation and use and to outside influences that encourage use.
Descriptors
Adolescent, Adolescent Behavior/ethnology/psychology, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Humans, India/epidemiology, Male, Peer Group, Poverty, Prevalence, Self Efficacy, Smoking/epidemiology, Social Class, Social Environment, Students/statistics & numerical data, Surveys and Questionnaires, Tobacco Use Disorder/epidemiology, Urban Population/statistics & numerical data
Links
Book Title
Database
Publisher
Data Source
Authors
Mathur,C., Stigler,M. H., Perry,C. L., Arora,M., Reddy,K. S.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Differences in puff topography, toxicant exposure, and subjective response between waterpipe tobacco smoking men and women. 2018
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Experimental and clinical psychopharmacology
Periodical, Abbrev.
Exp.Clin.Psychopharmacol.
Pub Date Free Form
Volume
26
Issue
5
Start Page
440
Other Pages
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
American Psychological Association
Data Source
google
Authors
Soule, Eric K, Ramôa, Carolina, Eissenberg, Thomas, Cobb, Caroline O
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Differences in puff topography, toxicant exposure, and subjective response between waterpipe tobacco smoking men and women. 2018
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Experimental and clinical psychopharmacology
Periodical, Abbrev.
Exp.Clin.Psychopharmacol.
Pub Date Free Form
Volume
26
Issue
5
Start Page
440
Other Pages
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
American Psychological Association
Data Source
google
Authors
Soule, Eric K, Ramôa, Carolina, Eissenberg, Thomas, Cobb, Caroline O
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Differences in puff topography, toxicant exposure, and subjective response between waterpipe tobacco smoking men and women. 2018
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Experimental and clinical psychopharmacology
Periodical, Abbrev.
Exp.Clin.Psychopharmacol.
Pub Date Free Form
Volume
26
Issue
5
Start Page
440
Other Pages
Notes
Place of Publication
ISSN/ISBN
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
Publisher
American Psychological Association
Data Source
google
Authors
Soule, Eric K, Ramôa, Carolina, Eissenberg, Thomas, Cobb, Caroline O
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Differences in quit attempts between non-Hispanic Black and White daily smokers: the role of smoking motives 2014 University of California, Los Angeles, Department of Psychology, United States.; University of California, Los Angeles, Department of Psychology, United States.; University of California, Los Angeles, Department of Psychology, United States; University of
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
Dec
Volume
39
Issue
12
Start Page
1769
Other Pages
1772
Notes
LR: 20150805; CI: Published by Elsevier Ltd.; GR: M01 RR000865/RR/NCRR NIH HHS/United States; GR: R03 DA030898/DA/NIDA NIH HHS/United States; GR: UL1RR033176/RR/NCRR NIH HHS/United States; GR: UL1TR000124/TR/NCATS NIH HHS/United States; JID: 7603486; NIHM
Place of Publication
England
ISSN/ISBN
1873-6327; 0306-4603
Accession Number
PMID: 25123344
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1016/j.addbeh.2014.07.001 [doi]
Output Language
Unknown(0)
PMID
25123344
Abstract
INTRODUCTION: The prevalence of smoking across racial/ethnic groups has declined over the years, yet racial health disparities for smoking persist. Studies indicate that non-Hispanic Black smokers attempt to quit smoking more often compared to non-Hispanic White smokers but are less successful at doing so. Research suggests that motives to quit smoking differ by race, however, less is known about the role of motives to smoke in explaining racial differences in attempts to quit smoking. METHODS: This study examined whether smoking motives accounted for the differential rates in quit attempts between non-Hispanic Black (n=155) and non-Hispanic White (n=159) smokers. Data were culled from a larger study of heavy-drinking smokers. The Wisconsin Index of Smoking Dependence Motives (WISDM) assessed motives to smoke. RESULTS: As expected, Black and White smokers reported similar smoking patterns, yet Black smokers reported higher rates of failed attempts to quit smoking than White smokers. Findings indicated that Black, compared to White, smokers endorsed lower scores in the negative reinforcement, positive reinforcement, and taste WISDM subscales and scores in these subscales mediated the relationship between race and quit attempts. CONCLUSIONS: In this study, Blacks, compared to Whites, endorsed lower motives to smoke, which are generally associated with successful quit attempts, yet they experienced more failed attempts to quit smoking. This study demonstrates racial health disparities at the level of smoking motives and suggests that Black smokers remain vulnerable to failed quit attempts despite reporting lower motives to smoke.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Bacio,G.A., Guzman,I.Y., Shapiro,J.R., Ray,L.A.
Original/Translated Title
URL
Date of Electronic
20140731
PMCID
PMC4320691
Editors
Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms 2008 Laboratory of Infectious Diseases, Third Department of Pediatrics, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, Greece.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Antimicrobial Agents and Chemotherapy
Periodical, Abbrev.
Antimicrob.Agents Chemother.
Pub Date Free Form
Jan
Volume
52
Issue
1
Start Page
357
Other Pages
360
Notes
LR: 20140904; JID: 0315061; 0 (Antifungal Agents); 0 (Azoles); 0 (Echinocandins); OID: NLM: PMC2223899; 2007/10/15 [aheadofprint]; ppublish
Place of Publication
United States
ISSN/ISBN
0066-4804; 0066-4804
Accession Number
PMID: 17938192
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
AAC.00856-07 [pii]
Output Language
Unknown(0)
PMID
17938192
Abstract
The activities of voriconazole, posaconazole, caspofungin, and anidulafungin against Candida albicans and Candida parapsilosis biofilms were evaluated. In contrast to planktonic cells, the MICs for voriconazole and posaconazole for the biofilms of the two species were high (>or=256 and >64 mg/liter, respectively) but relatively low for the echinocandins caspofungin and anidulafungin (<or=1 and <or=2 mg/liter, respectively).
Descriptors
Antifungal Agents/pharmacology, Azoles/pharmacology, Biofilms/drug effects, Candida/classification/drug effects, Candida albicans/drug effects, Echinocandins/pharmacology, Humans, Microbial Sensitivity Tests
Links
Book Title
Database
Publisher
Data Source
Authors
Katragkou,A., Chatzimoschou,A., Simitsopoulou,M., Dalakiouridou,M., Diza-Mataftsi,E., Tsantali,C., Roilides,E.
Original/Translated Title
URL
Date of Electronic
20071015
PMCID
PMC2223899
Editors