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Cigarettes and waterpipe smoking among medical students in Syria: a cross-sectional study 2008 Department of Family & Community Medicine, Damascus University, Damascus, Syria. qutaybah83@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Periodical, Abbrev.
Int.J.Tuberc.Lung Dis.
Pub Date Free Form
Sep
Volume
12
Issue
9
Start Page
1085
Other Pages
1091
Notes
LR: 20151119; GR: R01 DA024876/DA/NIDA NIH HHS/United States; GR: R01 DA024876-01/DA/NIDA NIH HHS/United States; GR: R01 DA024876-01/DA/NIDA NIH HHS/United States; JID: 9706389; NIHMS69735; OID: NLM: NIHMS69735; OID: NLM: PMC2553239; ppublish
Place of Publication
France
ISSN/ISBN
1027-3719; 1027-3719
Accession Number
PMID: 18713509
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
Output Language
Unknown(0)
PMID
18713509
Abstract
OBJECTIVES: To investigate tobacco use, beliefs and attitudes among medical students in Syria. METHODS: A cross-sectional study of a random sample of 570 medical students (first and fifth year) registered at the Damascus University Faculty of Medicine in 2006-2007. We used a self-administered questionnaire for demo-graphic information, smoking behaviour (cigarette, waterpipe), family and peer smoking, attitudes and beliefs about smoking and future role in advising patients to quit smoking. RESULTS: The overall prevalence of tobacco use was 10.9% for cigarettes (15.8% men, 3.3% women), 23.5% for waterpipe (30.3% men, 13.4% women) and 7.3% for both (10.1% men, 3.1% women). Both smoking methods were more popular among the fifth year students (15.4% and 27%) compared to their younger counterparts (6.6% and 19.7%). Regular smoking patterns predominated for cigarettes (62%), while occasional use patterns predominated for waterpipes (83%). More than two thirds of students (69%) thought they might not address or would have difficulty addressing smoking in their future patients. CONCLUSION: The level of tobacco use among Syrian medical students is alarming and highlights the rapidly changing patterns of waterpipe use, especially among female students. Medical schools should work harder to tackle this phenomenon and address it more efficiently in their curricula.
Descriptors
Adult, Confidence Intervals, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Humans, Logistic Models, Male, Odds Ratio, Prevalence, Sex Factors, Smoking/epidemiology/psychology, Students, Medical/statistics & numerical data, Surveys and Questionnaires, Syria/epidemiology, Universities
Links
Book Title
Database
Publisher
Data Source
Authors
Almerie,M. Q., Matar,H. E., Salam,M., Morad,A., Abdulaal,M., Koudsi,A., Maziak,W.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC2553239
Editors
Is concern about waterpipe tobacco smoking warranted? 2008
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Aust N Z J Public Health
Periodical, Abbrev.
Aust.N.Z.J.Public Health
Pub Date Free Form
Volume
32
Issue
2
Start Page
181
Other Pages
2
Notes
ID: 18412692
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Health Promotion, Smoking, Social Marketing, Tobacco Smoke Pollution, Adolescent, Adult, Female, Health Surveys, Humans, Male, Middle Aged, New South Wales
Links
http://dx.doi.org/10.1111/j.1753-6405.2008.00198.x
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Carroll,Therese, Poder,Natasha, Perusco,Andrew
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe tobacco smoking on a U.S. College campus: prevalence and correlates 2008 Department of Psychology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia 23298-0205, USA. teissenb@vcu.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Periodical, Abbrev.
J.Adolesc.Health
Pub Date Free Form
May
Volume
42
Issue
5
Start Page
526
Other Pages
529
Notes
LR: 20140921; GR: R01 CA103827/CA/NCI NIH HHS/United States; GR: R01 CA103827-04/CA/NCI NIH HHS/United States; GR: R01 DA011082/DA/NIDA NIH HHS/United States; GR: R01 DA011082-10/DA/NIDA NIH HHS/United States; GR: R01 TW005962/TW/FIC NIH HHS/United States
Place of Publication
United States
ISSN/ISBN
1879-1972; 1054-139X
Accession Number
PMID: 18407049
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.jadohealth.2007.10.004 [doi]
Output Language
Unknown(0)
PMID
18407049
Abstract
PURPOSE: Waterpipe tobacco smoking is reported to be growing in popularity, particularly among college students. This study examined the prevalence of waterpipe tobacco smoking prevalence and perceptions in a university-based population. METHOD: This was a cross-sectional Internet-based survey of first-year university students, which examined waterpipe tobacco smoking and other tobacco use, risk perceptions, influences, and perceived social acceptability. RESULTS: Waterpipe tobacco smoking within the past 30 days was reported by 20% (151/744). Relative to never users, users were more likely to perceive waterpipe tobacco smoking as less harmful than cigarette use. CONCLUSIONS: Because waterpipe tobacco smoking is increasing in prevalence and because it can involve toxicant inhalation at even greater levels than with cigarette smoking, it represents a growing public health issue.
Descriptors
Adolescent, Adult, Attitude to Health, Cross-Sectional Studies, Female, Humans, Male, Peer Group, Prevalence, Smoking, Social Environment, Students, United States, Universities
Links
Book Title
Database
Publisher
Data Source
Authors
Eissenberg,T., Ward,K. D., Smith-Simone,S., Maziak,W.
Original/Translated Title
URL
Date of Electronic
20071221
PMCID
PMC2362063
Editors
Exhaled carbon monoxide with waterpipe use in US students 2008
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
JAMA
Periodical, Abbrev.
JAMA
Pub Date Free Form
Volume
299
Issue
1
Start Page
36
Other Pages
8
Notes
ID: 18167404
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Air Pollution, Indoor/analysis, Carbon Monoxide/analysis, Exhalation, Smoking/trends, Tobacco Smoke Pollution/analysis, Adolescent, Adult, Charcoal, Female, Humans, Inhalation, Male, Smoking/adverse effects, Students, United States
Links
http://dx.doi.org/10.1001/jama.2007.6
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
El-Nachef,Wael, Hammond,S. K.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Cigarette and waterpipe smoking among Lebanese adolescents, a cross-sectional study, 2003-2004 2008 Department of Epidemiology and Population Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon. ze02@aub.edu.lb
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Feb
Volume
10
Issue
2
Start Page
309
Other Pages
314
Notes
LR: 20151119; JID: 9815751; ppublish
Place of Publication
England
ISSN/ISBN
1462-2203; 1462-2203
Accession Number
PMID: 18236295
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1080/14622200701825775 [doi]
Output Language
Unknown(0)
PMID
18236295
Abstract
Waterpipe or "argileh" is a form of smoking other than cigarettes that is currently spreading among people of all ages. The objective of the present study was to assess tobacco smoking practices (waterpipe and/or cigarette) among public and private adolescent school students in Beirut, Lebanon. A sample of 2,443 students selected from 10 private and 3 public schools with intermediate/secondary classes filled out a self-administered anonymous questionnaire that inquired about sociodemographic characteristics, and behavior about tobacco smoking. Binary analysis was performed as well as three regression models for the relationship between exclusive cigarettes smoking, exclusive waterpipe smoking and both cigarettes and waterpipe as the dependent variables and gender, type of school, and class as the independent variables. The current prevalence of cigarettes smoking was 11.4%, and that of waterpipe smoking was 29.6%. Gender was significantly associated with cigarettes (OR=3.2, 95% CI 1.8-5.6) but not waterpipe smoking. Public school students were, respectively, 3.2 (95% CI 1.8-5.6) and 1.7 (95% CI 1.4-2.1) times more likely to be exclusive cigarettes smokers, and exclusive waterpipe smokers. Class was not significantly associated with exclusive cigarette smoking; however, students attending secondary classes were 1.3 (95% CI 1.1-1.6) times more likely to be exclusive waterpipe smokers. The reasons behind the high prevalence of both types of smoking are presented and discussed. The present study calls for school-based prevention programs and other types of interventions such as tax increases, and age-restrictions on tobacco sales. More aggressive interventions to disseminate education and awareness among parents and students altogether are warranted.
Descriptors
Adolescent, Confidence Intervals, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Humans, Lebanon/epidemiology, Life Style, Male, Odds Ratio, Peer Group, Risk Factors, Risk-Taking, School Health Services/organization & administration, Smoking/epidemiology/psychology, Social Environment, Students/psychology/statistics & numerical data, Surveys and Questionnaires, Tobacco Use Disorder/epidemiology/prevention & control
Links
Book Title
Database
Publisher
Data Source
Authors
El-Roueiheb,Z., Tamim,H., Kanj,M., Jabbour,S., Alayan,I., Musharrafieh,U.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Genotoxic effects of waterpipe smoking on the buccal mucosa cells 2008
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Mutat Res
Periodical, Abbrev.
Mutat.Res.
Pub Date Free Form
Volume
655
Issue
2-Jan
Start Page
36
Other Pages
40
Notes
ID: 18662802
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Waterpipe smoking is popular in many parts of the world. Micronuclei (MN) evaluation in the exfoliated oral cells of smokers is a non-invasive technique for evaluation of possible tobacco harm. We aimed to assess whether MN levels are higher in waterpipe smokers than in never smokers. We examined oral smears of 128 adult male waterpipe smokers and 78 males who never smoked tobacco in rural Egypt. The total number of MN per 1000 cells per subject, and the number of MN-containing cells per individual were compared. We observed a higher level of total MN in waterpipe smokers (10 +/- 4) than in never smokers (4 +/- 2, p < 0.001). A similar difference was found for the mean number of affected cells per individual (8 +/- 3 vs. 4 +/- 1.62, p < 0.001). MN levels were not significantly dose related. This study is among the first to assess the association between waterpipe smoking and a cytogenetic measure of tobacco harm. The twofold increase in MN level is consistent with previous reports of MN in cigarette smokers. More research is needed to determine if such MN levels are predictive of future health consequences.
Descriptors
Mouth Mucosa/drug effects, Mutagens/toxicity, Smoking/adverse effects, Water, Adult, Age Factors, Demography, Humans, Male, Micronuclei, Chromosome-Defective/chemically induced, Middle Aged
Links
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568951/?tool=pubmed; http://dx.doi.org/10.1016/j.mrgentox.2008.06.014
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
El-Setouhy,Maged, Loffredo,Christopher A., Radwan,Ghada, Abdel Rahman,Rehab, Mahfouz,Eman, Israel,Ebenezer, Mohamed,Mostafa K., Ayyad,Sohair B. A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
A pleasure among friends: how narghile (waterpipe) smoking differs from cigarette smoking in Syria 2008 Syrian Center for Tobacco Studies, PO Box 16542, Aleppo, Syria. fadi@scts-sy.org
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Apr
Volume
17
Issue
2
Start Page
e3
Other Pages
Notes
GR: R01-TW05962/TW/FIC NIH HHS/United States; GR: R01DA024876-01/DA/NIDA NIH HHS/United States; GR: R03-TW07233/TW/FIC NIH HHS/United States; JID: 9209612; ppublish
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 18375726
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM
DOI
10.1136/tc.2007.020529 [doi]
Output Language
Unknown(0)
PMID
18375726
Abstract
BACKGROUND: Throughout the Eastern Mediterranean region (EMR), tobacco is used primarily in two forms: cigarette smoking and waterpipe (called narghile (nar-GIL-eh) in Syria) smoking. OBJECTIVE: To explore whether narghile smokers are different from cigarette smokers in how their smoking habits are embedded in their everyday lives. METHODS: One-to-one interviews with 16 adult narghile smokers and 16 adult cigarette smokers about their feelings, experiences and beliefs regarding their initiation, use patterns, and attempts to quit. FINDINGS: Narghile smokers found that narghile was a pleasurable social experience embedded in cultural rituals. By contrast, cigarette smokers saw their cigarette smoking as a mundane, oppressive, personal addiction. Narghile smokers generally started in their 20s and found that smoking narghile fostered a sense of togetherness and cultural identity, while cigarette smokers started in their early teens, males having started to becoming a "real man". Unlike cigarette smokers who felt stigmatised, narghile smokers generally felt that smoking narghile was socially accepted. Cigarette smokers believed that cigarettes were harmful to their health and harmful to those around them, but narghile smokers believed smoking narghile was relatively harmless to themselves or to others. Unlike cigarette smokers who used cigarettes to manage stress, narghile smokers used narghile for entertainment, leisure, and escape. However, frequent narghile smokers confessed that they felt addicted in much the same way as cigarette smokers. Cigarette smokers and narghile smokers viewed quitting as a matter of will and conviction. Most cigarette smokers had tried to quit. Very few narghile smokers had ever tried to quit, and most were not interested in quitting. Disturbingly, some cigarette smokers had tried to quit cigarettes by switching to smoking narghile, but later relapsed to smoking cigarettes. CONCLUSIONS: This exploratory study suggests that Syrian narghile smokers are different from Syrian cigarette smokers in their perceptions and beliefs about their smoking, and in their smoking patterns and lived experiences with tobacco. Our findings indicate that further in-depth research is need in the EMR to understand both modes of smoking to develop effective mode-specific prevention and cessation approaches. This study also raises concerns about a possible pattern where cigarette smokers are using narghile as a method for quitting cigarettes, and then relapsing.
Descriptors
Adult, Aged, Culture, Female, Friends, Humans, Male, Middle Aged, Motivation, Smoking/psychology, Smoking Cessation, Syria
Links
Book Title
Database
Publisher
Data Source
Authors
Hammal,F., Mock,J., Ward,K. D., Eissenberg,T., Maziak,W.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe smoking in students: prevalence, risk factors, symptoms of addiction, and smoke intake. Evidence from one British university 2008 Department of Primary Care & General Practice, University of Birmingham, Birmingham, B15 2TT, UK. DHJ242@adf.bham.ac.uk
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
BMC public health
Periodical, Abbrev.
BMC Public Health
Pub Date Free Form
22-May
Volume
8
Issue
Start Page
174
Other Pages
2458-8-174
Notes
LR: 20151119; JID: 100968562; 059QF0KO0R (Water); 7U1EE4V452 (Carbon Monoxide); OID: NLM: PMC2413225; 2007/11/22 [received]; 2008/05/22 [accepted]; 2008/05/22 [aheadofprint]; epublish
Place of Publication
England
ISSN/ISBN
1471-2458; 1471-2458
Accession Number
PMID: 18498653
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1186/1471-2458-8-174 [doi]
Output Language
Unknown(0)
PMID
18498653
Abstract
BACKGROUND: Anecdotal reports suggest waterpipe smoking is becoming common in students in western countries. The aim was to examine prevalence, risk factors, symptoms of addiction, and smoke intake. METHODS: This was a cross-sectional survey of students with subsidiary survey of regular waterpipe user and survey of exhaled carbon monoxide (CO) before and after waterpipe smoking in customers of a waterpipe cafe. 937 students of Birmingham University completed the initial survey with a follow up of 21 regular waterpipe smokers. 63 customers of a waterpipe cafe near the University completed the study of CO intake. RESULTS: 355 (37.9%, 95% confidence intervals (CI) 34.8 to 41.1%) students had tried waterpipes, the prevalence of trying rising with duration at University. 75 (8.0%, 95%CI 6.4 to 10.0%) were regular smokers, similar to the prevalence of cigarette smoking (9.4%). Although cigarette smoking was the major risk factor for being a regular waterpipe smoker, odds ratio (95%CI) 2.77 (1.52 to 5.06), 65% of waterpipe smokers did not smoke cigarettes. Seven of 21 (33.3%) regular waterpipe smokers experienced cravings. Nearly all regular waterpipe users thought it less harmful than smoking cigarettes. The mean (standard deviation) rise in CO was 37.4 (25.8)ppm, nearly twice as high as a typical cigarette smoker seeking cessation treatment. CONCLUSION: Waterpipe smoking is a common part of student culture in one British university, as in the Middle East and in the United States. It poses a potential threat to public health, with evidence of dependence and high smoke intake.
Descriptors
Adolescent, Adult, Carbon Monoxide/analysis, Confidence Intervals, Cross-Sectional Studies, Female, Follow-Up Studies, Great Britain/epidemiology, Health Behavior, Humans, Male, Prevalence, Restaurants, Risk Factors, Smoking/epidemiology/psychology, Students/psychology/statistics & numerical data, Surveys and Questionnaires, Tobacco Use Disorder/epidemiology, Universities, Water
Links
Book Title
Database
Publisher
Data Source
Authors
Jackson,D., Aveyard,P.
Original/Translated Title
URL
Date of Electronic
20080522
PMCID
PMC2413225
Editors
Knowledge, attitudes and practice of university students regarding waterpipe smoking in Pakistan 2008 Section of Pulmonary and Critical Care Medicine, Aga Khan University, Karachi, Pakistan. alijawaid84@gmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Periodical, Abbrev.
Int.J.Tuberc.Lung Dis.
Pub Date Free Form
Sep
Volume
12
Issue
9
Start Page
1077
Other Pages
1084
Notes
LR: 20151119; JID: 9706389; 059QF0KO0R (Water); ppublish
Place of Publication
France
ISSN/ISBN
1027-3719; 1027-3719
Accession Number
PMID: 18713508
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
Output Language
Unknown(0)
PMID
18713508
Abstract
OBJECTIVES: To study the awareness, perceptions and practice of university students in Karachi, Pakistan, with regard to shisha (waterpipe) smoking. DESIGN: Cross-sectional survey conducted among students at four different universities of Karachi, selected through random cluster sampling. RESULTS: A total of 450 participants, 59.6% males (n=268) and 40.4% females (n=182), were included in the study. About half of the participants reported having ever smoked shisha (n=241, 53.6%). On examining factors associated with starting shisha smoking, curiosity was found to be the most common reason (n=148, 61.4%), followed by pleasure-seeking (n=113, 46.9%), peer pressure (n=55, 22.8%), boredom (n=43, 17.8%) and stress (n=26, 10.8%). Of 241 participants who had ever smoked waterpipes, the majority (n=149, 61.8%) were current smokers. A vast majority of participants (n=269, 60%) considered waterpipe smoking to be less unhealthy than cigarette smoking. Boredom in youth, use of waterpipe in leisure activities and peer pressure were identified as the most common reasons for the escalating popularity of waterpipe smoking in Pakistan. CONCLUSIONS: Waterpipe smoking is very popular among Pakistani university students, and knowledge among university students about the dangers of waterpipe smoking is alarmingly low.
Descriptors
Adult, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Humans, Logistic Models, Male, Pakistan/epidemiology, Prevalence, Risk Factors, Smoking/epidemiology, Students/statistics & numerical data, Surveys and Questionnaires, Universities, Water
Links
Book Title
Database
Publisher
Data Source
Authors
Jawaid,A., Zafar,A. M., Rehman,T. U., Nazir,M. R., Ghafoor,Z. A., Afzal,O., Khan,J. A.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The waterpipe: time for action 2008 University of Memphis, Syrian Center for Tobacco Studies, Memphis, TN 38152, USA. wmaziak@memphis.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addiction (Abingdon, England)
Periodical, Abbrev.
Addiction
Pub Date Free Form
Nov
Volume
103
Issue
11
Start Page
1763
Other Pages
1767
Notes
LR: 20140913; GR: R01 DA024876/DA/NIDA NIH HHS/United States; GR: R01 DA024876-01/DA/NIDA NIH HHS/United States; GR: R01 DA024876-01/DA/NIDA NIH HHS/United States; JID: 9304118; 059QF0KO0R (Water); 7U1EE4V452 (Carbon Monoxide); NIHMS68007; OID: NLM: NIHMS
Place of Publication
England
ISSN/ISBN
1360-0443; 0965-2140
Accession Number
PMID: 18778388
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1111/j.1360-0443.2008.02327.x [doi]
Output Language
Unknown(0)
PMID
18778388
Abstract
The waterpipe, known in many cultures under different shapes and names (e.g. hookah, shisha, narghile), is a centuries-old tobacco use method that is witnessing a world-wide surge in popularity. This popularity is most noticeable among youths, and is surpassing cigarette smoking among this group in some societies. Many factors may have contributed to the recent waterpipe spread, including the introduction of sweetened/flavored waterpipe tobacco (known as Maassel), its reduced-harm perception, the thriving cafe culture, mass media and the internet. The passage of smoke through water on its way to the smoker underlies much of the common misperception that waterpipe use is less harmful than cigarettes. The health/addictive profile of waterpipe compared to cigarettes is largely unresearched and is likely to be influenced by the properties of smoke, duration and frequency of use, type of tobacco used, volume of smoke inhaled and the contribution of charcoal. However, the accumulation of evidence about the harmful and addictive potential of waterpipe use is outpacing the public health response to this health risk. A timely public health and policy action is needed in order to curb the emerging waterpipe smoking epidemic.
Descriptors
Adolescent, Attitude to Health, Carbon Monoxide, Health Behavior, Health Knowledge, Attitudes, Practice, Humans, Middle East/epidemiology/ethnology, Public Health, Risk-Taking, Smoking/prevention & control/psychology/trends, Tobacco Use Disorder/epidemiology/prevention & control/psychology, Water
Links
Book Title
Database
Publisher
Data Source
Authors
Maziak,W.
Original/Translated Title
URL
Date of Electronic
20080904
PMCID
PMC2588474
Editors