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Assessment of DNA damage using chromosomal aberrations assay in lymphocytes of waterpipe smokers 2012
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Print(0)
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Journal Article
Periodical, Full
Int J Occup Med Environ Health
Periodical, Abbrev.
Int.J.Occup.Med.Environ.Health
Pub Date Free Form
Volume
25
Issue
3
Start Page
218
Other Pages
24
Notes
ID: 22729491
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
OBJECTIVES: The aim of this study was to investigate the genotoxicity of waterpipe smoking in the lymphocytes of waterpipe smokers using chromosomal aberrations (CAs) assay. MATERIALS AND METHODS: Fifty waterpipe smokers and 18 healthy non-smokers volunteered to participate in the study. Additionally, 18 heavy cigarette smokers were recruited for comparison. Chromosomal aberrations (CAs) assay was used to evaluate DNA damage in the lymphocytes. RESULTS: The results showed that similarly to cigarette smoking, waterpipe smoking significantly increased the frequencies of CAs (p
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MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Alsatari,Enas S., Azab,Mohammad, Khabour,Omar F., Alzoubi,Karem H., Sadiq,May F.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
In vitro cytotoxicity and mutagenicity of mainstream waterpipe smoke and its functional consequences on alveolar type II derived cells 2012
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Print(0)
Ref Type
Journal Article
Periodical, Full
Toxicol Lett
Periodical, Abbrev.
Toxicol.Lett.
Pub Date Free Form
Volume
211
Issue
3
Start Page
220
Other Pages
31
Notes
ID: 22516759
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
INTRODUCTION: While waterpipe tobacco smoking has become a global phenomenon, its potential health consequences are poorly understood. In this manuscript, we report the in vitro mutagenicity of waterpipe smoke condensate (WSC), the alteration in cellular parameters of lung alveolar cells in response to WSC exposure and discuss the implication of cellular responses in the pathophysiology of chronic obstructive pulmonary disease (COPD). METHODS: The mainstream WSC was generated using a standard laboratory machine protocol. We assessed its mutagenicity using Ames test. In addition, we studied the effect of WSC on the proliferation and cell cycle of alveolar type II cells and vascular endothelial cells. We also assessed the effect of WSC on the expression of genes involved in cell cycle arrest and inflammation. RESULTS: Within the range of tested doses, WSC did not elicit sufficient response to be considered mutagenic in any of the strains tested (TA98, TA100, TA102, and TA97a) but were found to be toxic for strains TA97a and TA102 at the highest tested doses. However, WSC induced cell cycle arrest and cellular senescence mediated by the p53-p21 pathway. Also our study indicated that WSC induced an increase in the transcriptional expression of matrix metalloproteinases, MMP-2 and MMP-9 and an immune response regulator, Toll Like Receptor-4. CONCLUSION: The data reported here represent the first in vitro demonstration of the effect of waterpipe smoke on cellular parameters providing evidence of the potential involvement of WPS in the pathogenesis of COPD through impairing cellular growth and inducing inflammation.
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Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Rammah,Mayyasa, Dandachi,Farah, Salman,Rola, Shihadeh,Alan, El-Sabban, Marwan
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe smoking: a new tobacco pandemic entailing severe health risks? 2012
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Print(0)
Ref Type
Journal Article
Periodical, Full
Arch Toxicol
Periodical, Abbrev.
Arch.Toxicol.
Pub Date Free Form
Volume
86
Issue
8
Start Page
1161
Other Pages
2
Notes
ID: 22684767
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://dx.doi.org/10.1007/s00204-012-0885-4
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Luch,Andreas
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe smoking 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
East Mediterr Health J
Periodical, Abbrev.
East.Mediterr.Health J.
Pub Date Free Form
Volume
18
Issue
10
Start Page
995
Other Pages
995
Notes
ID: 23301352
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://pesquisa.bvsalud.org/ghl/resource/en/mdl-23301352
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Waterpipe tobacco smoking and cigarette equivalence 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Br J Gen Pract
Periodical, Abbrev.
Br.J.Gen.Pract.
Pub Date Free Form
Volume
62
Issue
596
Start Page
127
Other Pages
127
Notes
ID: 22429419
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Masters,Nigel, Tutt,Catherine, Yaseen,Nisar
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Anesthesia implications of waterpipe use 2012
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Print(0)
Ref Type
Journal Article
Periodical, Full
J Clin Anesth
Periodical, Abbrev.
J.Clin.Anesth.
Pub Date Free Form
Volume
24
Issue
2
Start Page
137
Other Pages
40
Notes
ID: 22414706
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
The waterpipe is an ancient Middle Eastern tobacco delivery system, which is also known as hookah, shisha, or narghile, and it is gaining widespread use. Waterpipes are often perceived as less dangerous than cigarettes. The amount of smoke inhaled in a waterpipe session may equal that produced by more than 100 cigarettes with high nicotine, carbon monoxide, and carcinogen intake. A case of significantly elevated intraoperative carboxyhemoglobin level and decreased oxyhemoglobin saturation in a patient with recent waterpipe use is presented.
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Links
http://dx.doi.org/10.1016/j.jclinane.2011.05.005
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Kesner,Kimberly L., Ramaiah,Vijay K., Hemmer,Laura B., Koht,Antoun
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
The Waterpipe: A New Global Threat to CV Health? 2012
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Glob Heart
Periodical, Abbrev.
Pub Date Free Form
Volume
7
Issue
2
Start Page
179
Other Pages
81
Notes
ID: 25691314
Place of Publication
ISSN/ISBN
Accession Number
Language
en
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Descriptors
Links
http://dx.doi.org/10.1016/j.gheart.2012.03.003
Book Title
Database
MEDLINE; http://www.globalhealthlibrary.net/
Publisher
Data Source
Authors
Maziak,Wasim
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Acute effects of waterpipe tobacco smoking: a double-blind, placebo-control study 2011 Department of Psychology, Virginia Commonwealth University, Richmond, VA 23298-0205, USA.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Drug and alcohol dependence
Periodical, Abbrev.
Drug Alcohol Depend.
Pub Date Free Form
1-Jul
Volume
116
Issue
3-Jan
Start Page
102
Other Pages
109
Notes
LR: 20151119; CI: Published by Elsevier Ireland Ltd.; GR: F31 DA028102/DA/NIDA NIH HHS/United States; GR: F31 DA028102-02/DA/NIDA NIH HHS/United States; GR: F31DA028102/DA/NIDA NIH HHS/United States; GR: R01 CA120142/CA/NCI NIH HHS/United States; GR: R01
Place of Publication
Ireland
ISSN/ISBN
1879-0046; 0376-8716
Accession Number
PMID: 21277706
Language
eng
SubFile
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.drugalcdep.2010.11.026 [doi]
Output Language
Unknown(0)
PMID
21277706
Abstract
BACKGROUND: Waterpipe tobacco smoking usually involves heating flavored tobacco with charcoal and inhaling the resulting smoke after it has passed through water. Waterpipe tobacco smoking increases heart rate and produces subjective effects similar to those reported by cigarette smokers. These responses are thought to be nicotine-mediated, though no placebo-control studies exist. Accordingly, this double-blind, placebo-control study compared the acute physiological and subjective effects of waterpipe tobacco smoking to those produced when participants used a waterpipe to smoke a flavor-matched, tobacco-free preparation. METHODS: Occasional waterpipe tobacco smokers (n = 37; 2-5 monthly smoking episodes for >/= 6 months) completed two double-blind, counterbalanced sessions that differed by product: preferred brand/flavor of waterpipe tobacco or flavor-matched, tobacco-free preparation. For each 45-min, ad lib smoking episode blood and expired air CO were sampled, cardiovascular and respiratory response were measured, and subjective response was assessed. RESULTS: Waterpipe tobacco smoking significantly increased mean (+/- SEM) plasma nicotine concentration (3.6 +/- 0.7 ng/ml) and heart rate (8.6 +/- 1.4 bpm) while placebo did not (0.1 +/- 0.0 ng/ml; 1.3 +/- 0.9b pm). For carboxyhemoglobin (COHb) and expired air CO, significant increases were observed for tobacco (3.8 +/- 0.4%; 27.9 +/- 2.6 ppm) and for placebo (3.9 +/- 0.4%; 27.7 +/- 3.3 ppm) with no differences across condition. Independent of condition, symptoms of nicotine/tobacco abstinence (e.g., "urges to smoke", "anxious") were reduced and direct effects (e.g., "dizzy", "satisfy") increased. DISCUSSION: These results from the first placebo-control study of waterpipe tobacco smoking demonstrate that waterpipe-induced heart rate increases are almost certainly mediated by nicotine though the subjective effects observed in these occasional smokers were not.
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Database
Publisher
Data Source
Authors
Blank,M.D., Cobb,C.O., Kilgalen,B., Austin,J., Weaver,M.F., Shihadeh,A., Eissenberg,T.
Original/Translated Title
URL
Date of Electronic
20110201
PMCID
PMC3098931
Editors
Nicotine exposure in daily waterpipe smokers and its relation to puff topography 2011 School of Public Health, University of Memphis, Memphis, TN, USA. wmaziak@memphis.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Addictive Behaviors
Periodical, Abbrev.
Addict.Behav.
Pub Date Free Form
Apr
Volume
36
Issue
4
Start Page
397
Other Pages
399
Notes
LR: 20151119; CI: Copyright (c) 2010; GR: CA120142/CA/NCI NIH HHS/United States; GR: DA024876/DA/NIDA NIH HHS/United States; GR: R01 DA024876/DA/NIDA NIH HHS/United States; GR: R01 DA024876-04/DA/NIDA NIH HHS/United States; JID: 7603486; 0 (Tobacco Smoke
Place of Publication
England
ISSN/ISBN
1873-6327; 0306-4603
Accession Number
PMID: 21185126
Language
eng
SubFile
Journal Article; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.addbeh.2010.11.013 [doi]
Output Language
Unknown(0)
PMID
21185126
Abstract
Waterpipe tobacco smoking is increasing in popularity worldwide and available evidence point to its addictive and harmful potential. This study is conducted to assess nicotine exposure in daily waterpipe smokers, and its correlation with puff topography parameters. Sixty-one waterpipe tobacco smokers (56 males; mean age+/-SD, 30.9+/-9.5years; mean number of weekly waterpipe smoking episodes 7.8+/-5.7) abstained from smoking for at least 24h, and then smoked tobacco from a waterpipe ad libitum in a laboratory setting. During the session puff topography parameters were monitored continuously, and pre- and post-smoking expired-air CO was measured. Before and after smoking, venous blood was sampled for the assessment of plasma nicotine using Gas Chromatography-Mass Spectrometry. The average pre- and post-smoking expired-air CO was 4+/-1.7 and 35.5+/-32.7ppm, respectively (i.e., a CO boost of 31.5ppm, p<.001 mean="" plasma="" nicotine="" concentration="" increased="" from="" pre-smoking="" to="" post-smoking="" boost="" was="" correlated="" with="" total="" session="" time="" correlation="" coefficient="" r=".31," p=".04)," cumulative="" puff="" duration="" and="" smoke="" inhaled="" in="" the="" these="" data="" show="" considerable="" exposure="" daily="" waterpipe="" smokers="" that="" is="" a="" function="" of="" smoking="" patterns.="">
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ltd
Data Source
Authors
Maziak,W., Rastam,S., Shihadeh,A.L., Bazzi,A., Ibrahim,I., Zaatari,G.S., Ward,K.D., Eissenberg,T.
Original/Translated Title
URL
Date of Electronic
20101202
PMCID
PMC3040439
Editors
Prevalence and correlates of waterpipe tobacco smoking by college students in North Carolina 2011 Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC 27157, United States. ESutfin@wfubmc.edu
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Drug and alcohol dependence
Periodical, Abbrev.
Drug Alcohol Depend.
Pub Date Free Form
1-May
Volume
115
Issue
2-Jan
Start Page
131
Other Pages
136
Notes
LR: 20150204; CI: Copyright (c) 2011; GR: R01 AA014007/AA/NIAAA NIH HHS/United States; GR: R01 AA014007-09/AA/NIAAA NIH HHS/United States; GR: R01AA014007/AA/NIAAA NIH HHS/United States; JID: 7513587; NIHMS271506; OID: NLM: NIHMS271506; OID: NLM: PMC30896
Place of Publication
Ireland
ISSN/ISBN
1879-0046; 0376-8716
Accession Number
PMID: 21353750
Language
eng
SubFile
Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM
DOI
10.1016/j.drugalcdep.2011.01.018 [doi]
Output Language
Unknown(0)
PMID
21353750
Abstract
BACKGROUND: Known most commonly in the U.S. as "hookah," waterpipe tobacco smoking appears to be growing among college students. Despite beliefs that waterpipe use is safer than cigarette smoking, research to date (albeit limited) has found health risks of waterpipe smoking are similar to those associated with cigarette smoking, including lung cancer, respiratory illness, and periodontal disease. The goals of this study were to estimate the prevalence of use among a large, multi-institution sample of college students and identify correlates of waterpipe use, including other health-risk behaviors (i.e., cigarette smoking, alcohol, marijuana, and other illicit drug use) and availability of commercial waterpipe tobacco smoking venues. METHODS: A cross-sectional sample of 3770 college students from eight universities in North Carolina completed a web-based survey in fall 2008. RESULTS: Forty percent of the sample reported ever having smoked tobacco from a waterpipe, and 17% reported current (past 30-day) waterpipe tobacco smoking. Correlates associated with current waterpipe use included demographic factors (male gender, freshman class); other health-risk behaviors (daily and nondaily cigarette smoking, alcohol use, marijuana use, other illicit drug use); perceiving waterpipe tobacco smoking as less harmful than regular cigarettes; and having a commercial waterpipe venue near campus. CONCLUSIONS: The results highlight the popularity of waterpipe tobacco smoking among college students and underscore the need for more research to assess the public health implications of this growing trend.
Descriptors
Links
Book Title
Database
Publisher
Elsevier Ireland Ltd
Data Source
Authors
Sutfin,E.L., McCoy,T.P., Reboussin,B.A., Wagoner,K.G., Spangler,J., Wolfson,M.
Original/Translated Title
URL
Date of Electronic
20110225
PMCID
PMC3089695
Editors