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Short-term nose-only water-pipe (shisha) smoking exposure accelerates coagulation and causes cardiac inflammation and oxidative stress in mice 2015 Department of Physiology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE.
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Journal Article
Periodical, Full
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Periodical, Abbrev.
Cell.Physiol.Biochem.
Pub Date Free Form
Volume
35
Issue
2
Start Page
829
Other Pages
840
Notes
CI: (c) 2015; JID: 9113221; 0 (Interleukin-6); 0 (Tumor Necrosis Factor-alpha); 0 (interleukin-6, mouse); 2014/10/29 [accepted]; 2015/01/30 [aheadofprint]; ppublish
Place of Publication
Switzerland
ISSN/ISBN
1421-9778; 1015-8987
Accession Number
PMID: 25634761
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1159/000369741 [doi]
Output Language
Unknown(0)
PMID
25634761
Abstract
BACKGROUND/AIM: Water-pipe smoking (WPS) has acquired worldwide popularity, and is disseminating particularly rapidly in Europe and North America. However, little is known about the short-term cardiovascular effects of WPS. METHODS: Presently, we assessed the short-term cardiovascular effects of nose-only exposure to mainstream WPS in BALB/c mice for 30 min/day for 5 consecutive days. Control mice were exposed to air. At the end of the exposure period, several cardiovascular endpoints were measured. RESULTS: WPS did not affect the number of leukocytes and the plasma concentrations of C-reactive protein, tumor necrosis factor alpha (TNFalpha) and interleukin-6 (IL-6). Likewise, plasma levels of lipid peroxidation (LPO), reduced glutathione (GSH) and catalase were not affected by WPS. By contrast, WPS aggravated in vivo thrombosis by shortening the thrombotic occlusion time in pial arterioles and venules. The number of circulating platelets was reduced by WPS suggesting the occurrence of platelet aggregation in vivo. Elevated concentrations of fibrinogen and plasminogen activator inhibitor-1 were seen after the exposure to WPS. Blood samples taken from mice exposed to WPS and exposed to adenosine diphosphate showed more platelet aggregation. The heart concentrations of IL-6 and TNFalpha were augmented by WPS. Likewise, heart levels of LPO, reactive oxygen species and the antioxidants catalase and GSH were increased by WPS. However, the systolic blood pressure and heart rate were not affected by WPS. CONCLUSION: It can be concluded that short-term exposure to WPS exerts procoagulatory effects and induce cardiac inflammation and oxidative stress. At the time point investigated, there was no evidence for blood inflammation or oxidative stress.
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Links
Book Title
Database
Publisher
S. Karger AG, Basel
Data Source
Authors
Nemmar,A., Yuvaraju,P., Beegam,S., Ali,B.H.
Original/Translated Title
URL
Date of Electronic
20150130
PMCID
Editors
Early pulmonary events of nose-only water pipe (shisha) smoking exposure in mice 2015 Department of Physiology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates anemmar@uaeu.ac.ae anemmar@hotmail.com.; Department of Physiology, College of Medicine and Health Sciences, United Arab Emirat
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Physiological reports
Periodical, Abbrev.
Physiol.Rep.
Pub Date Free Form
Mar
Volume
3
Issue
3
Start Page
10.14814/phy2.12258
Other Pages
Notes
LR: 20150421; CI: (c) 2015; JID: 101607800; OID: NLM: PMC4393146; OTO: NOTNLM; ppublish
Place of Publication
United States
ISSN/ISBN
2051-817X; 2051-817X
Accession Number
PMID: 25780090
Language
eng
SubFile
Journal Article
DOI
10.14814/phy2.12258 [doi]
Output Language
Unknown(0)
PMID
25780090
Abstract
Water pipe smoking (WPS) is increasing in popularity and prevalence worldwide. Convincing data suggest that the toxicants in WPS are similar to that of cigarette smoke. However, the underlying pathophysiologic mechanisms related to the early pulmonary events of WPS exposure are not understood. Here, we evaluated the early pulmonary events of nose-only exposure to mainstream WPS generated by commercially available honey flavored "moasel" tobacco. BALB/c mice were exposed to WPS 30 min/day for 5 days. Control mice were exposed using the same protocol to atmospheric air only. We measured airway resistance using forced oscillation technique, and pulmonary inflammation was evaluated histopathologically and by biochemical analysis of bronchoalveolar lavage (BAL) fluid and lung tissue. Lung oxidative stress was evaluated biochemically by measuring the level of reactive oxygen species (ROS), lipid peroxidation (LPO), reduced glutathione (GSH), catalase, and superoxide dismutase (SOD). Mice exposed to WPS showed a significant increase in the number of neutrophils (P
Descriptors
Links
Book Title
Database
Publisher
The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society
Data Source
Authors
Nemmar,A., Al Hemeiri,A., Al Hammadi,N., Yuvaraju,P., Beegam,S., Yasin,J., Elwasila,M., Ali,B.H., Adeghate,E.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC4393146
Editors
Effect of shisha (waterpipe) smoking on lung functions and fractional exhaled nitric oxide (FeNO) among Saudi young adult shisha smokers 2014 Department of Physiology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461 Saudi Arabia. smeo@ksu.edu.sa.; Department of Physiology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461 Saudi Arabia. K_a_Z_h@hotmail
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of environmental research and public health
Periodical, Abbrev.
Int.J.Environ.Res.Public.Health.
Pub Date Free Form
17-Sep
Volume
11
Issue
9
Start Page
9638
Other Pages
9648
Notes
JID: 101238455; 31C4KY9ESH (Nitric Oxide); OID: NLM: PMC4199040; 2014/06/15 [received]; 2014/09/02 [revised]; 2014/09/03 [accepted]; epublish
Place of Publication
Switzerland
ISSN/ISBN
1660-4601; 1660-4601
Accession Number
PMID: 25233010
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.3390/ijerph110909638 [doi]
Output Language
Unknown(0)
PMID
25233010
Abstract
Shisha (waterpipe) smoking is becoming a more prevalent form of tobacco consumption, and is growing worldwide, particularly among the young generation in the Middle East. This cross-sectional study aimed to determine the effects of shisha smoking on lung functions and Fractional Exhaled Nitric Oxide (FeNO) among Saudi young adults. We recruited 146 apparently healthy male subjects (73 control and 73 shisha smokers). The exposed group consisted of male shisha smokers, with mean age 21.54 +/- 0.41 (mean +/- SEM) range 17-33 years. The control group consisted of similar number (73) of non-smokers with mean age 21.36 +/- 0.19 (mean +/- SEM) range 18-28 years. Between the groups we considered the factors like age, height, weight, gender, ethnicity and socioeconomic status to estimate the impact of shisha smoking on lung function and fractional exhaled nitric oxide. Lung function test was performed by using an Spirovit-SP-1 Electronic Spirometer. Fractional Exhaled Nitric Oxide (FeNO) was measured by using Niox Mino. A significant decrease in lung function parameters FEV1, FEV1/FVC Ratio, FEF-25%, FEF-50%, FEF-75% and FEF-75-85% was found among shisha smokers relative to their control group. There was also a significant reduction in the Fractional Exhaled Nitric Oxide among Shisha smokers compared to control group.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Meo,S.A., AlShehri,K.A., AlHarbi,B.B., Barayyan,O.R., Bawazir,A.S., Alanazi,O.A., Al-Zuhair,A.R.
Original/Translated Title
URL
Date of Electronic
20140917
PMCID
PMC4199040
Editors
Harmful effects of shisha: literature review 2014 Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.; Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.; Dow Medical College, Dow Un
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International archives of medicine
Periodical, Abbrev.
Int.Arch.Med.
Pub Date Free Form
4-Apr
Volume
7
Issue
Start Page
16
Other Pages
7682-7-16. eCollection 2014
Notes
LR: 20140624; JID: 101317943; OID: NLM: PMC4003490; 2014 [ecollection]; 2013/12/05 [received]; 2014/03/26 [accepted]; 2014/04/04 [epublish]; epublish
Place of Publication
England
ISSN/ISBN
1755-7682; 1755-7682
Accession Number
PMID: 24708750
Language
eng
SubFile
Journal Article; Review
DOI
10.1186/1755-7682-7-16 [doi]
Output Language
Unknown(0)
PMID
24708750
Abstract
Tobacco is a preventable cause of morbidity and mortality across the world. A recently infamous way of smoking tobacco is shisha. Shisha smoking is also known as water pipe, hookah and Narghile smoking. The percentage of shisha smokers is on the rise rapidly spanning the globe. A literature review was conducted to identify all evidence on the epidemiological variations and health effects of shisha smoking. "Pub med" is used as a searching tool to identify all relevant empirical studies conducted worldwide. A qualitative overview of evidence is presented. Exposure to Shisha smoking is significantly associated with low infant weight, heart rate variations, hyperglycemia and hypertriglyceridemia. Increased risk of carcinoma is also leagued with it including carcinomas of the pancreas and lung being at the forefront. In conclusion, this review identifies grounds of several adverse conditions being associated with the habit of shisha smoking. It also evaluates the relevant epidemiological variations around the globe. The review culminates in the importance of enlightening shisha smokers regarding its deleterious effects.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Aslam,H.M., Saleem,S., German,S., Qureshi,W.A.
Original/Translated Title
URL
Date of Electronic
20140404
PMCID
PMC4003490
Editors
Squamous cell carcinoma and keratoacanthoma of the lower lip associated with 'Goza' and 'Shisha' smoking 1999 El-Hakim, I.E., Dept. of Oral/Maxillofacial Surgery, Hadayek Helwan 11433, Cairo, Egypt
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of dermatology
Periodical, Abbrev.
Int.J.Dermatol.
Pub Date Free Form
1999/
Volume
38
Issue
2
Start Page
108
Other Pages
110
Notes
Place of Publication
ISSN/ISBN
0011-9059
Accession Number
Language
SubFile
DOI
Output Language
Unknown(0)
PMID
Abstract
Background: A positive correlation between lip and buccal cancers and pipe smoking has been suggested. Various types of crude and manufactured tobacco products are consumed by smoking, chewing, and snuff dipping habits. 'Shisha' and 'Goza' smoking are widely practiced in the Middle East. The 'hubble-bubble' method and apparatus are used. These smoking habits are hazardous to health, causing obstructive lung disease, and may be important predisposing factors for the development of oral cancers. Case reports: Two cases of squamous cell carcinoma and a case of keratoacanthoma localized to the lower lip are presented in well-known 'Shisha' and 'Goza' smokers. Conclusions: 'Shisha' and 'Goza' smoking have adverse effects on general health and may predispose to oral cancer. An extensive epidemiological study should be performed to determine whether this type of smoking habit is associated with a statistically increased incidence of squamous cell carcinoma and keratoacanthoma of the lips.
Descriptors
adult, article, case report, excision, human, keratoacanthoma, lip carcinoma, lower lip, male, Middle East, mouth cancer, smoking, squamous cell carcinoma, tobacco
Links
Book Title
Database
Embase; MEDLINE
Publisher
Data Source
Embase
Authors
El-Hakim,I. E., Uthman,M. A. E.
Original/Translated Title
URL
Date of Electronic
PMCID
Editors
Porsche Design's Shisha 2 hits the Lebanese market 2016 Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.; Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.; Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
10-Feb
Volume
Issue
Start Page
Other Pages
Notes
LR: 20160213; JID: 9209612; OTO: NOTNLM; aheadofprint
Place of Publication
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 26865638
Language
ENG
SubFile
JOURNAL ARTICLE
DOI
tobaccocontrol-2015-052709 [pii]
Output Language
Unknown(0)
PMID
26865638
Abstract
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Alaouie,H., Nakkash,R., Afifi,R.
Original/Translated Title
URL
Date of Electronic
20160210
PMCID
Editors
Water pipe (shisha) smoking among male students of medical colleges in the eastern region of Saudi Arabia 2010 Family and Community Medicine Department, College of Medicine, King Faisal University, Dammam, Saudi Arabia. aztaha@hotmail.com
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Annals of Saudi medicine
Periodical, Abbrev.
Ann.Saudi Med.
Pub Date Free Form
May-Jun
Volume
30
Issue
3
Start Page
222
Other Pages
226
Notes
LR: 20151119; JID: 8507355; CIN: Ann Saudi Med. 2011 Jan-Feb;31(1):94-5. PMID: 21245608; CIN: Ann Saudi Med. 2010 Jul-Aug;30(4):330; author reply 330. PMID: 20622355; CIN: Ann Saudi Med. 2010 Nov-Dec;30(6):493-4; author reply 494. PMID: 21060162; OID: NLM
Place of Publication
Saudi Arabia
ISSN/ISBN
0975-4466; 0256-4947
Accession Number
PMID: 20427939
Language
eng
SubFile
Journal Article; IM
DOI
10.4103/0256-4947.62838 [doi]
Output Language
Unknown(0)
PMID
20427939
Abstract
BACKGROUND AND OBJECTIVES: Shisha smoking, one of the commonest methods of smoking tobacco among Arabs, increases the risk of cardiovascular and respiratory diseases. The objective of this study was to determine the prevalence of shisha smoking among male students of three colleges and to identify factors associated with shisha smoking. METHODS: This cross-sectional study included 500 male students of three colleges (medicine, applied medical sciences and dentistry). Data were collected from 371 students using a self-administered questionnaire. RESULTS: The overall prevalence of shisha smoking was 12.6% (8.6% shisha only and 4.0% both shisha and cigarettes). Thirty students (63.8%) started shisha smoking at ages of 16 to 18 years. Seven students (15%) smoked shisha daily. Cafiotas or restaurants were the favorite places for smoking (70.2% of students). There was a high prevalence of shisha smoking among students whose mothers had a secondary (19.1%) and higher (53.3%) education. CONCLUSIONS: There was a high prevalence of shisha smoking among university students. The majority of students started shisha smoking at a young age. Public health measures, including the banning of smoking in public places are recommended.
Descriptors
Confidence Intervals, Cross-Sectional Studies, Geography, Health Behavior, Health Knowledge, Attitudes, Practice, Humans, Male, Prevalence, Risk Factors, Risk-Taking, Saudi Arabia/epidemiology, Schools, Medical, Smoking/epidemiology, Students, Dental, Students, Medical, Surveys and Questionnaires
Links
Book Title
Database
Publisher
Data Source
Authors
Taha,A. Z., Sabra,A. A., Al-Mustafa,Z. Z., Al-Awami,H. R., Al-Khalaf,M. A., Al-Momen,M. M.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC2886873
Editors
Health warning labelling practices on narghile (shisha, hookah) waterpipe tobacco products and related accessories 2010 Health Behavior and Education Department, Center for Research on Population and Health, Faculty of Health Sciences, American University of Beirut, PO, Riad El Solh, Beirut 1107 2020, Lebanon. rima.nakkash@aub.edu.lb
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Tobacco control
Periodical, Abbrev.
Tob.Control
Pub Date Free Form
Jun
Volume
19
Issue
3
Start Page
235
Other Pages
239
Notes
LR: 20141203; JID: 9209612; OID: NLM: PMC2989164; ppublish
Place of Publication
England
ISSN/ISBN
1468-3318; 0964-4563
Accession Number
PMID: 20501497
Language
eng
SubFile
Journal Article; Research Support, Non-U.S. Gov't; IM
DOI
10.1136/tc.2009.031773 [doi]
Output Language
Unknown(0)
PMID
20501497
Abstract
BACKGROUND: Waterpipe tobacco smoking prevalence is increasing around the globe despite current evidence that smoke emissions are toxic and contain carcinogenic compounds. OBJECTIVE: To evaluate current health warning labelling practices on waterpipe tobacco products and related accessories. METHODS: All waterpipe tobacco products, as well as waterpipe accessories, were purchased from Lebanon and a convenience sample was obtained from Dubai (United Arab Emirates), Palestine, Syria, Jordan, Bahrain, Canada, Germany and South Africa. FINDINGS: Of the total number of waterpipe tobacco products collected from Lebanon, the majority had textual health warning labels covering on average only 3.5% of total surface area of the package. Misleading descriptors were commonplace on waterpipe tobacco packages and related accessories. CONCLUSIONS: There are no WHO FCTC compliant waterpipe-specific health warning labels on waterpipe tobacco products and related accessories. Introducing health warnings on waterpipe tobacco products and accessories will probably have worldwide public health benefits.
Descriptors
Global Health, Health Promotion/methods, Humans, Inhalation Exposure/adverse effects/prevention & control, Product Labeling, Smoking/adverse effects/prevention & control
Links
Book Title
Database
Publisher
Data Source
Authors
Nakkash,R., Khalil,J.
Original/Translated Title
URL
Date of Electronic
PMCID
PMC2989164
Editors
Prevalence of waterpipe (Shisha, Narghille, Hookah) use among adults in Great Britain and factors associated with waterpipe use: data from cross-sectional Online Surveys in 2012 and 2013 2014 Institute of Primary Care and Public Health, School of Medicine, Cardiff University, Cardiff, UK; granta2@cardiff.ac.uk.; ASH Scotland, Edinburgh, UK;; ASH, Action on Smoking and Health, London, UK.
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Periodical, Abbrev.
Nicotine Tob.Res.
Pub Date Free Form
Jul
Volume
16
Issue
7
Start Page
931
Other Pages
938
Notes
CI: (c) The Author 2014; JID: 9815751; 2014/02/18 [aheadofprint]; ppublish
Place of Publication
England
ISSN/ISBN
1469-994X; 1462-2203
Accession Number
PMID: 24550183
Language
eng
SubFile
Journal Article; IM
DOI
10.1093/ntr/ntu015 [doi]
Output Language
Unknown(0)
PMID
24550183
Abstract
INTRODUCTION: We assessed the prevalence and frequency of waterpipe smoking among adults (aged 18+ years) in Great Britain (GB) and determined demographic factors associated with use. METHODS: We used cross-sectional representative population surveys conducted online in 2012 and 2013. A total of 12,436 adults in 2012 and 12,171 in 2013 were recruited from a commercial online survey panel. RESULTS: The prevalence of ever use of waterpipe across both survey years combined was 11.6% (95% confidence interval [CI] = 11.0-12.1). Frequent use (at least once or twice a month) was 1.0% (95% CI = 0.8-1.2) and was similar in both 2012 and 2013. There was some suggestion of increased ever but not frequent use among 18-24-year-olds between survey years. After adjustment for covariates, females had lower odds of ever waterpipe use than males (odds ratio [OR] = 0.71, 95% CI = 0.63-0.79), those in the lowest social grade had lower odds of use compared to those in the highest social grade (OR = 0.43, 95% CI = 0.35-0.54), older people were at much lower odds of ever use than younger people, ever having smoked cigarettes increased odds of ever waterpipe use, and being Asian (OR = 1.84, 95% CI = 1.39-2.45) or of mixed ethnicity (OR = 2.36, 95% CI = 1.64-3.40) increased likelihood of ever use compared to White ethnicity. CONCLUSIONS: Frequent waterpipe smoking was relatively rare in these representative samples of the GB adult population, and prevalence was similar between 2012 and 2013. Continued monitoring and targeted interventions are appropriate.
Descriptors
Links
Book Title
Database
Publisher
. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco
Data Source
Authors
Grant,A., Morrison,R., Dockrell,M.J.
Original/Translated Title
URL
Date of Electronic
20140218
PMCID
Editors
Shisha Smoking Practices, Use Reasons, Attitudes, Health Effects and Intentions to Quit among Shisha Smokers in Malaysia 2016 Julius Centre University of Malaya (JCUM), Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. wonglp@ummc.edu.my.; Julius Centre University of Malaya (JCUM), Department of Social and Prev
Source Type
Print(0)
Ref Type
Journal Article
Periodical, Full
International journal of environmental research and public health
Periodical, Abbrev.
Int.J.Environ.Res.Public.Health.
Pub Date Free Form
19-Jul
Volume
13
Issue
7
Start Page
10.3390/ijerph13070726
Other Pages
Notes
LR: 20160802; JID: 101238455; OID: NLM: PMC4962267; OTO: NOTNLM; 2016/05/04 [received]; 2016/05/20 [revised]; 2016/05/24 [accepted]; epublish
Place of Publication
Switzerland
ISSN/ISBN
1660-4601; 1660-4601
Accession Number
PMID: 27447655
Language
eng
SubFile
Journal Article; IM
DOI
10.3390/ijerph13070726 [doi]
Output Language
Unknown(0)
PMID
27447655
Abstract
Despite its popularity, shisha smoking practices, reasons for its use, attitudes, detrimental health effects and intention to quit among shisha users in Malaysia have never been investigated. A total of 503 shisha users responded to a cross-sectional study conducted between July 2015 and March 2016. The majority of users were young people aged 21-30; a small minority were underage. The reasons for shisha use were its growing popularity as a favourite pastime activity and the perception of shisha use as cool and trendy. Just over half (57.3%) agree that shisha use exposes the smoker to large amounts of smoke and the majority were unsure about the health risks of shisha smoking compared to tobacco smoking. The three most common detrimental health effects reported by the study respondents were dry throat, headache and nausea. Regular shisha users have significantly higher detrimental health effects compared to no-regular shisha users. Shisha users with a duration of smoking of 6-12 months (odds ratio (OR) 3.212; 95% confidence interval (CI) 1.651-6.248) and 6 months and below (OR 2.601; 95% CI 1.475-4.584) were significantly more likely to have a higher proportion who intend quitting smoking than shisha users of more than 12 months duration.
Descriptors
Links
Book Title
Database
Publisher
Data Source
Authors
Wong,L.P., Alias,H., Aghamohammadi,N., Aghazadeh,S., Hoe,V.C.
Original/Translated Title
URL
Date of Electronic
20160719
PMCID
PMC4962267
Editors