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Title	Pub Year	Author Sort ascending	SearchLink
Arteriovenous bubbles following cold water sport dives: relation to right-to-left shunting	2000	Department of Neurology, Justus-Liebig-University, Giessen, Germany.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Neurology Periodical, Abbrev. Neurology Pub Date Free Form 12-Dec Volume 55 Issue 11 Start Page 1741 Other Pages 1743 Notes LR: 20081121; JID: 0401060; ppublish Place of Publication UNITED STATES ISSN/ISBN 0028-3878; 0028-3878 Accession Number PMID: 11113236 Language eng SubFile Journal Article; AIM; IM DOI Output Language Unknown(0) PMID 11113236 Abstract Neurologic injury subsequent to decompression from diving may be due to paradoxical arterialization of venous gas emboli. Of 40 divers who performed 53 open water dives after being tested for a patent foramen ovale (PFO), arterial gas emboli were detected in 7 of 13 dives, which resulted in venous bubbles. In five of these seven dives, there was evidence of a PFO by contrast transcranial Doppler sonography, indicating an increased risk of arterializing venous bubbles in divers with a PFO. Descriptors Adult, Cold Temperature/adverse effects, Decompression Sickness, Diving, Embolism, Air/physiopathology/ultrasonography, Female, Humans, Male, Middle Aged, Ultrasonography, Doppler Links Book Title Database Publisher Data Source Authors Gerriets,T., Tetzlaff,K., Liceni,T., Schafer,C., Rosengarten,B., Kopiske,G., Algermissen,C., Struck,N., Kaps,M. Original/Translated Title URL Date of Electronic PMCID Editors
Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness?	2004	Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway. ulrik.wisloff@medisin.ntnu.no	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of physiology Periodical, Abbrev. J.Physiol. Pub Date Free Form 16-Mar Volume 555 Issue Pt 3 Start Page 825 Other Pages 829 Notes LR: 20140610; JID: 0266262; 0 (Nitric Oxide Donors); 16051-77-7 (isosorbide-5-mononitrate); 31C4KY9ESH (Nitric Oxide); IA7306519N (Isosorbide Dinitrate); OID: NLM: PMC1664873; 2004/01/14 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 0022-3751; 0022-3751 Accession Number PMID: 14724207 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1113/jphysiol.2003.055467 [doi] Output Language Unknown(0) PMID 14724207 Abstract Nitrogen dissolves in the blood during dives, but comes out of solution if divers return to normal pressure too rapidly. Nitrogen bubbles cause a range of effects from skin rashes to seizures, coma and death. It is believed that these bubbles form from bubble precursors (gas nuclei). Recently we have shown that a single bout of exercise 20 h, but not 48 h, before a simulated dive prevents bubble formation and protects rats from severe decompression sickness (DCS) and death. Furthermore, we demonstrated that administration of N(omega)-nitro-l-arginine methyl ester, a non-selective inhibitor of NO synthase (NOS), turns a dive from safe to unsafe in sedentary but not exercised rats. Therefore based upon previous data an attractive hypothesis is that it may be possible to use either exercise or NO-releasing agents before a dive to inhibit bubble formation and thus protect against DCS. Consequently, the aims of the present study were to determine whether protection against bubble formation in 'diving' rats was provided by (1) chronic and acute administration of a NO-releasing agent and (2) exercise less than 20 h prior to the dive. NO given for 5 days and then 20 h prior to a dive to 700 kPa lasting 45 min breathing air significantly reduced bubble formation and prevented death. The same effect was seen if NO was given only 30 min before the dive. Exercise 20 h before a dive suppressed bubble formation and prevented death, with no effect at any other time (48, 10, 5 and 0.5 h prior to the dive). Pre-dive activities have not been considered to influence the growth of bubbles and thus the risk of serious DCS. The present novel findings of a protective effect against bubble formation and death by appropriately timed exercise and an NO-releasing agent may form the basis of a new approach to preventing serious decompression sickness. Descriptors Animals, Decompression Sickness/prevention & control, Diving, Female, Isosorbide Dinitrate/analogs & derivatives/pharmacology, Motor Activity/physiology, Nitric Oxide/physiology, Nitric Oxide Donors/pharmacology, Rats, Rats, Sprague-Dawley Links Book Title Database Publisher Data Source Authors Wisloff,U., Richardson,R. S., Brubakk,A. O. Original/Translated Title URL Date of Electronic 20040114 PMCID PMC1664873 Editors
Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation	2010	Department of Basic and Applied Medical Sciences, Ud'A Chieti-Pescara, Italy.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of applied physiology (Bethesda, Md.: 1985) Periodical, Abbrev. J.Appl.Physiol.(1985) Pub Date Free Form May Volume 108 Issue 5 Start Page 1077 Other Pages 1083 Notes LR: 20131121; JID: 8502536; 0 (ITGB3 protein, human); 0 (Integrin beta3); 0 (P-Selectin); 0 (Platelet Membrane Glycoprotein IIb); S88TT14065 (Oxygen); 2010/02/25 [aheadofprint]; ppublish Place of Publication United States ISSN/ISBN 1522-1601; 0161-7567 Accession Number PMID: 20185629 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1152/japplphysiol.01058.2009 [doi] Output Language Unknown(0) PMID 20185629 Abstract Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation in scuba divers was evaluated. Six volunteers participated in four diving protocols, with 2 wk of recovery between dives. On dive 1, before diving, all divers breathed normally for 20 min at the surface of the sea (Air). On dive 2, before diving, all divers breathed 100% oxygen for 20 min at the surface of the sea [normobaric oxygenation (NBO)]. On dive 3, before diving, all divers breathed 100% O2 for 20 min at 6 m of seawater [msw; hyperbaric oxygenation (HBO) 1.6 atmospheres absolute (ATA)]. On dive 4, before diving, all divers breathed 100% O2 for 20 min at 12 msw (HBO 2.2 ATA). Then they dove to 30 msw (4 ATA) for 20 min breathing air from scuba. After each dive, blood samples were collected as soon as the divers surfaced. Bubbles were measured at 20 and 50 min after decompression and converted to bubble count estimate (BCE) and numeric bubble grade (NBG). BCE and NBG were significantly lower in NBO than in Air [0.142+/-0.034 vs. 0.191+/-0.066 (P<0.05) and 1.61+/-0.25 vs. 1.89+/-0.31 (P<0.05), respectively] at 20 min, but not at 50 min. HBO at 1.6 ATA and 2.2 ATA has a similar significant effect of reducing BCE and NBG. BCE was 0.067+/-0.026 and 0.040+/-0.018 at 20 min and 0.030+/-0.022 and 0.020+/-0.020 at 50 min. NBG was 1.11+/-0.17 and 0.92+/-0.16 at 20 min and 0.83+/-0.18 and 0.75+/-0.16 at 50 min. Prebreathing NBO and HBO significantly alleviated decompression-induced platelet activation. Activation of CD62p was 3.0+/-0.4, 13.5+/-1.3, 10.7+/-0.9, 4.5+/-0.7, and 7.6+/-0.8% for baseline, Air, NBO, HBO at 1.6 ATA, and HBO at 2.2 ATA, respectively. The data show that prebreathing oxygen, more effective with HBO than NBO, decreases air bubbles and platelet activation and, therefore, may be beneficial in reducing the development of decompression sickness. Descriptors Administration, Inhalation, Adult, Decompression/adverse effects, Decompression Sickness/blood/physiopathology/prevention & control/ultrasonography, Diving, Embolism, Air/blood/physiopathology/prevention & control/ultrasonography, Humans, Hyperbaric Oxygenation, Immersion, Inhalation, Integrin beta3/blood, Male, Middle Aged, Oxygen/administration & dosage, P-Selectin/blood, Platelet Activation, Platelet Membrane Glycoprotein IIb/blood, Time Factors, Ultrasonography, Doppler, Young Adult Links Book Title Database Publisher Data Source Authors Bosco,G., Yang,Z. J., Di Tano,G., Camporesi,E. M., Faralli,F., Savini,F., Landolfi,A., Doria,C., Fano,G. Original/Translated Title URL Date of Electronic 20100225 PMCID Editors
Blood platelet count and bubble formation after a dive to 30 msw for 30 min	2008	Departement des facteurs humains, Centre de Recherches du Service de Sante des Armees, La Tronche, France. jm.pontier@free.fr	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Aviation, Space, and Environmental Medicine Periodical, Abbrev. Aviat.Space Environ.Med. Pub Date Free Form Dec Volume 79 Issue 12 Start Page 1096 Other Pages 1099 Notes JID: 7501714; ppublish Place of Publication United States ISSN/ISBN 0095-6562; 0095-6562 Accession Number PMID: 19070304 Language eng SubFile Journal Article; IM; S DOI Output Language Unknown(0) PMID 19070304 Abstract INTRODUCTION: Previous human studies reported that platelet count (PC) is decreased following decompression. Platelet aggregation and adherence to the bubble surface has been demonstrated in severe decompression sickness (DCS). The present study was designed to clarify the relationship between post-dive changes in blood PC and the level of bubble formation in divers. METHODS: There were 40 healthy experienced divers who were assigned to 1 experimental group (N = 30) with an open-sea air dive to 30 msw for 30 min in field conditions and 1 control group (N = 10) without hyperbaric exposure. Bubble grades were monitored with a pulsed Doppler according to the Spencer scale and Kissman integrated severity score (KISS). Blood samples for red blood cell counts (RBC), hematocrit (Hct), and PC were taken 1 h before and after exposure in two groups. RESULTS: None of the divers developed any signs of DCS. In two groups, the results showed significant increase in RBC count and Hct related with hemoconcentration and no change in PC. Divers with a high KISS score (39 +/- 5.8; mean +/- SD) presented a significantly more pronounced percent fall in PC than divers with a lower KISS score. We found a significant correlation between the percent fall in PC after a dive and the bubble KISS score. DISCUSSION: The present study highlighted a relationship between the post-dive decrease in PC and the magnitude of bubble level after decompression. Our primary result is that the post-dive decrease in PC could be a predictor of decompression severity after diving. Descriptors Adult, Decompression/adverse effects, Decompression Sickness/blood/etiology, Diving/adverse effects, Embolism, Air/blood/etiology, Health Status Indicators, Humans, Male, Platelet Aggregation, Platelet Count, Pressure, Prospective Studies, Time Factors Links Book Title Database Publisher Data Source Authors Pontier,J. M., Jimenez,C., Blatteau,J. E. Original/Translated Title URL Date of Electronic PMCID Editors
Flying after diving: should recommendations be reviewed? In-flight echocardiographic study in bubble-prone and bubble-resistant divers	2015	DAN Europe Research Division, Contrada Padune 11, 64026 Roseto degli, Abruzzi (TE), Italy, Phone: +39(0)85-893-0333, Fax: +39-(0)85-893-0050, E-mail: dcialoni@daneurope.org.; DAN Europe Research Division, Roseto degli Abruzzi, Italy.; DAN Europe Research	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Diving and hyperbaric medicine Periodical, Abbrev. Diving.Hyperb.Med. Pub Date Free Form Mar Volume 45 Issue 1 Start Page 10 Other Pages 15 Notes JID: 101282742; OTO: NOTNLM; 2014/12/12 [received]; 2015/01/17 [accepted]; ppublish Place of Publication Australia ISSN/ISBN 1833-3516; 1833-3516 Accession Number PMID: 25964033 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI Output Language Unknown(0) PMID 25964033 Abstract INTRODUCTION: Inert gas accumulated after multiple recreational dives can generate tissue supersaturation and bubble formation when ambient pressure decreases. We hypothesized that this could happen even if divers respected the currently recommended 24-hour pre-flight surface interval (PFSI). METHODS: We performed transthoracic echocardiography (TTE) on a group of 56 healthy scuba divers (39 male, 17 female) as follows: first echo--during the outgoing flight, no recent dives; second echo--before boarding the return flight, after a multiday diving week in the tropics and a 24-hour PFSI; third echo--during the return flight at 30, 60 and 90 minutes after take-off. TTE was also done after every dive during the week's diving. Divers were divided into three groups according to their 'bubble-proneness': non-bubblers, occasional bubblers and consistent bubblers. RESULTS: During the diving, 23 subjects never developed bubbles, 17 only occasionally and 16 subjects produced bubbles every day and after every dive. Bubbles on the return flight were observed in eight of the 56 divers (all from the 'bubblers' group). Two subjects who had the highest bubble scores during the diving were advised not to make the last dive (increasing their PFSI to approximately 36 hours), and did not demonstrate bubbles on the return flight. CONCLUSIONS: Even though a 24-hour PFSI is recommended on the basis of clinical trials showing a low risk of decompression sickness (DCS), the presence of venous gas bubbles in-flight in eight of 56 divers leads us to suspect that in real-life situations DCS risk after such a PFSI is not zero. Descriptors Links Book Title Database Publisher Data Source Authors Cialoni,D., Pieri,M., Balestra,C., Marroni,A. Original/Translated Title URL Date of Electronic PMCID Editors
A deep stop during decompression from 82 fsw (25 m) significantly reduces bubbles and fast tissue gas tensions	2004	DAN Europe Foundation, Research Division.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc Periodical, Abbrev. Undersea Hyperb.Med. Pub Date Free Form Summer Volume 31 Issue 2 Start Page 233 Other Pages 243 Notes LR: 20050627; JID: 9312954; CIN: Undersea Hyperb Med. 2005 Mar-Apr;32(2):85-8; author reply 89-92. PMID: 15926299; ppublish Place of Publication United States ISSN/ISBN 1066-2936; 1066-2936 Accession Number PMID: 15485086 Language eng SubFile Evaluation Studies; Journal Article; IM; S DOI Output Language Unknown(0) PMID 15485086 Abstract In spite of many modifications to decompression algorithms, the incidence of decompression sickness (DCS) in scuba divers has changed very little. The success of stage, compared to linear ascents, is well described yet theoretical changes in decompression ratios have diminished the importance of fast tissue gas tensions as critical for bubble generation. The most serious signs and symptoms of DCS involve the spinal cord, with a tissue half time of only 12.5 minutes. It is proposed that present decompression schedules do not permit sufficient gas elimination from such fast tissues, resulting in bubble formation. Further, it is hypothesized that introduction of a deep stop will significantly reduce fast tissue bubble formation and neurological DCS risk. A total of 181 dives were made to 82 fsw (25 m) by 22 volunteers. Two dives of 25 min and 20 min were made, with a 3 hr 30 min surface interval and according to 8 different ascent protocols. Ascent rates of 10, 33 or 60 fsw/min (3, 10, 18 m/min) were combined with no stops or a shallow stop at 20 fsw (6 m) or a deep stop at 50 fsw (15 m) and a shallow at 20 fsw (6 m). The highest bubbles scores (8.78/9.97), using the Spencer Scale (SS) and Extended Spencer Scale (ESS) respectively, were with the slowest ascent rate. This also showed the highest 5 min and 10 min tissue loads of 48% and 75%. The lowest bubble scores (1.79/2.50) were with an ascent rate of 33 fsw (10 m/min) and stops for 5 min at 50 fsw (15 m) and 20 fsw (6 m). This also showed the lowest 5 and 10 min tissue loads at 25% and 52% respectively. Thus, introduction of a deep stop significantly reduced Doppler detected bubbles together with tissue gas tensions in the 5 and 10 min tissues, which has implications for reducing the incidence of neurological DCS in divers. Descriptors Atmospheric Pressure, Decompression/standards, Decompression Sickness/prevention & control/ultrasonography, Diving/adverse effects/standards, Humans, Reference Values, Regression Analysis, Time Factors Links Book Title Database Publisher Data Source Authors Marroni,A., Bennett,P. B., Cronje,F. J., Cali-Corleo,R., Germonpre,P., Pieri,M., Bonuccelli,C., Balestra,C. Original/Translated Title URL Date of Electronic PMCID Editors
Knowledge, attitudes, and practices of argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in Lebanon	2004	Chaaya, M., Dept. of Epidemiol. and Pop. Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addictive Behaviors Periodical, Abbrev. Addict.Behav. Pub Date Free Form / Volume 29 Issue 9 Start Page 1821 Other Pages 1831 Notes Place of Publication ISSN/ISBN 0306-4603 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Background: Currently, little is known about argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in the Arab world, despite emerging evidence on the adverse health effects of argileh smoking and well-established knowledge about the health risks of cigarette smoking during pregnancy. Objectives: The present study assesses pregnant Arab women's knowledge of chemical contents and related harmful effects of argileh and cigarettes, their attitudes towards smoking argileh and cigarettes, and their actual smoking of argileh and cigarettes, both before and during pregnancy. Methods: A stratified sample of 864 women from 23 health care centers in Lebanon completed a structured, interviewer-administered questionnaire. Information was collected on basic demographic variables, women's knowledge, attitudes, and cigarette and argileh smoking. Results: Women were partially knowledgeable about the health risks of cigarette smoking, knew little about the harmful ingredients of argileh smoking, and had many misconceptions regarding how argileh worked or how it can produce harm. Attitudes were permissive towards all forms of smoking. Almost one quarter (23%) of participants reported smoking during pregnancy, with 17% smoking only cigarettes, 4% smoking only argileh, and 1.5% smoking both cigarette and argileh. Conclusion: A significant and growing percentage of pregnant Arab women are smoking in Lebanon, with four cigarette smokers for every argileh smoker. Smoking behaviors are empirically linked with important gaps in knowledge and with permissive attitudes. These data may be used to design more effective prevention programs targeting this vulnerable population. Â© 2004 Elsevier Ltd. All rights reserved. Descriptors adult, article, attitude, behavior, smoking, controlled study, demography, female, human, Lebanon, pregnancy Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Chaaya,M., Jabbour,S., El-Roueiheb,Z., Chemaitelly,H. Original/Translated Title URL Date of Electronic PMCID Editors
Doppler bubble grades after diving and relevance of body fat	2012	Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, The Netherlands. n.a.schellart@amc.uva.nl	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Aviation, Space, and Environmental Medicine Periodical, Abbrev. Aviat.Space Environ.Med. Pub Date Free Form Oct Volume 83 Issue 10 Start Page 951 Other Pages 957 Notes LR: 20140131; JID: 7501714; CIN: Aviat Space Environ Med. 2014 Jan;85(1):84-5. PMID: 24479268; CIN: Aviat Space Environ Med. 2014 Jan;85(1):84. PMID: 24479267; ppublish Place of Publication United States ISSN/ISBN 0095-6562; 0095-6562 Accession Number PMID: 23066616 Language eng SubFile Journal Article; IM; S DOI Output Language Unknown(0) PMID 23066616 Abstract BACKGROUND: From the literature on venous gas embolism (VGE) and decompression sickness (DCS), it remains unclear whether body fat is a predisposing factor for VGE and DCS. Therefore, this study analyses body fat (range 16-44%) in relation to precordial VGE measured by Doppler bubble grades. Also examined is the effect of age (range 34-68 yr), body mass index (BMI; range 17-34 kg x m(-2)), and a model estimate of VO2(max) (maximal oxygen uptake; range 24-54 ml x kg(-1) x min(-1)). METHODS: Bubble grades were determined in 43 recreational divers after an open sea air dive of 40 min to 20 m. Doppler bubble grade scores were transformed to the logarithm of the number of bubbles/cm2, logB, and the logarithm of the Kissman Integrated Severity Score (KISS) to allow numerical analysis. Statistical analyses were performed with Pearson's regular and partial correlations, and uni- and multivariate linear regressions. RESULTS: For divers in their midlife (and older), the analyses indicate that neither body fat nor BMI stimulate bubble formation, since correlations were nonsignificant. In contrast, age and especially VO2(max) appeared to determine VGE. For these types of dives it was found that logB = -1.1 + 0.02 age - 0.04Vo2(max). CONCLUSION: Based on these data we conclude that body fat and BMI seem less relevant for diving. We recommend that medical examinations pay more attention to VO2(max) and age, and that international dive institutions come to a consensus regarding VO2(max) criteria. Descriptors Links Book Title Database Publisher Data Source Authors Schellart,N.A., Vellinga,T.P., van Dijk,F.J., Sterk,W. Original/Translated Title URL Date of Electronic PMCID Editors
Comparative analysis of the effects of hubble-bubble (Sheesha) and cigarette smoking on respiratory and metabolic parameters in hubble-bubble and cigarette smokers	2006	Al Mutairi, S.S., Department of Medicine, Faculty of Medicine, Safat 13110, Kuwait	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Respirology Periodical, Abbrev. Respirology Pub Date Free Form / Volume 11 Issue 4 Start Page 449 Other Pages 455 Notes Place of Publication ISSN/ISBN 1323-7799; 1440-1843 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objectives and background: Hazard of smoking tobacco is believed to be minimized by smoking hubble-bubble (HB) instead of cigarettes. Our aims were to (i) develop an assay for estimating nicotine and cotinine; and (ii) evaluate the effect of smoking on respiratory and metabolic parameters in cigarette and HB smokers. Methods: Urine samples were collected from 152 volunteer smokers (75 cigarette and 77 HB) as well as from 16 healthy controls. We optimized an HPLC method for the determination of nicotine and cotinine. Subjects were asked to complete a chronic respiratory symptoms questionnaire and to undergo spirometry. Fasting blood samples were collected for the determination of their lipid profile. Results: The intra-assay coefficients of variation for nicotine and cotinine were 16.6% and 6.6%, respectively. The mean of cotinine in cigarette smokers (1321.4 ng/mL) was significantly (P = 0.008) higher than the mean cotinine (677.6 ng/mL) in HB smokers. The mean nicotine level in cigarette smokers (1487.3 ng/mL) was significantly (P < 0.0001) higher than the mean nicotine (440.5 ng/mL) in HB smoker. The urinary cotinine and nicotine levels of the control subjects were lower than the detection levels of the assay. The mean high-density lipoprotein cholesterol was lower in cigarette smokers (0.99 mmol/L) compared with HB smoker smokers (1.02 mmol/L) but this was not significant (P = 0.28). Spirometric values were comparable among the three groups but the chronic respiratory symptoms in the smoking groups appeared at an earlier age in the HB smokers compared with the cigarettes smokers (P < 0.05). Conclusion: Smoking HB does not reduce the risk of tobacco exposure and it's potentially harmful metabolites on health. Â© 2006 Asian Pacific Society of Respirology. Descriptors cotinine, glucose, high density lipoprotein cholesterol, low density lipoprotein cholesterol, nicotine, triacylglycerol, adult, aged, analytic method, article, cholesterol blood level, chronic respiratory tract disease, smoking, controlled study, female, glucose blood level, high performance liquid chromatography, human, lipid blood level, lipid metabolism, major clinical study, male, observer variation, priority journal, questionnaire, spirometry, triacylglycerol blood level, urine level Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Al Mutairi,S. S., Shihab-Eldeen,A. A., Mojiminiyi,O. A., Anwar,A. A. Original/Translated Title URL Date of Electronic PMCID Editors
Laryngeal findings and acoustic changes in hubble-bubble smokers	2010		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Eur Arch Otorhinolaryngol Periodical, Abbrev. Eur.Arch.Otorhinolaryngol. Pub Date Free Form Volume 267 Issue 10 Start Page 1587 Other Pages 92 Notes ID: 20480370 Place of Publication ISSN/ISBN Accession Number Language en SubFile DOI Output Language Unknown(0) PMID Abstract The purpose of our investigation was to evaluate the laryngeal findings and acoustic changes in hubble-bubble smokers. A total of 42 subjects with history of hubble-bubble smoking were recruited for this study. A corresponding group with a history of cigarette smoking and controls were matched. All subjects underwent laryngeal video-endostroboscopic evaluation and acoustic analysis. In the hubble-bubble smoking group, 61.9% were males. The average age was 30.02 +/- 9.48 years and the average number of years of smoking was 8.09 +/- 6.45 years. Three subjects had dysphonia at the time of examination. The incidence of benign lesions of the vocal folds in the hubble-bubble group was 21.5%, with edema being the most common at 16.7% followed by cyst at 4.8%. The incidence of laryngeal findings was significantly higher in the hubble-bubble group compared to controls. In the cigarette-smoking group, the most common finding was vocal fold cyst in 14.8% followed by polyps in 7.4%, and edema, sulcus vocalis and granuloma. These findings were not significantly different from the hubble-bubble group except for the thick mucus, which was significantly higher in the latter. There were no significant changes in any of the acoustic parameters between hubble-bubble smokers and controls except for the VTI and MPT, which were significantly lower in the hubble-bubble group. In comparison with the cigarette-smoking group, hubble-bubble smokers had significantly higher Fundamental frequency and habitual pitch (p value 0.042 and 0.008, respectively). The laryngeal findings in hubble-bubble smokers are comparable to cigarette smokers. These laryngeal findings are not translated acoustically, as all the acoustic parameters are within normal range compared to controls. Descriptors Laryngeal Diseases/epidemiology, Larynx/pathology, Larynx/physiopathology, Smoking/adverse effects, Speech Acoustics, Voice Quality, Adult, Aerosols/adverse effects, Case-Control Studies, Female, Humans, Laryngeal Diseases/pathology, Laryngeal Diseases/physiopathology, Male, Stroboscopy, Young Adult Links http://dx.doi.org/10.1007/s00405-010-1273-4 Book Title Database MEDLINE; http://www.globalhealthlibrary.net/ Publisher Data Source Authors Hamdan,Abdul-latif, Sibai,Abla, Oubari,Dima, Ashkar,Jihad, Fuleihan,Nabil Original/Translated Title URL Date of Electronic PMCID Editors

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