WTS database

Title	Pub Year Sort ascending	Author	SearchLink
Nicotine content in tobacco used in hubble-bubble smoking	2004	Hadidi, K.A., Forensic Med./Toxicology Division, Faculty of Medicine, University of Jordan, Amman 11942, Jordan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Saudi medical journal Periodical, Abbrev. Saudi Med.J. Pub Date Free Form / Volume 25 Issue 7 Start Page 912 Other Pages 917 Notes Place of Publication ISSN/ISBN 0379-5284 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objective: To determine the nicotine content of commonly used tobacco in hubble-bubble (HB) and compare it with that found in cigarettes. Methods: Analysis of nicotine content of 13 commercial brands of HB tobacco was carried out using gas chromatography over an 8 month period; November 2002 through to June 2003 at the Toxicology Laboratory, University of Jordan. Results: A wide variation in nicotine content in all brands was noticed with an average of 8.32 mg/g tobacco, range (1.8-44.3 mg/g). The average nicotine content in each HB head (20 gm) of unflavored tobacco was (713mg/head) and flavored tobacco has (67mg/head). One head of unflavored tobacco has nicotine equivalent to 70 regular cigarettes. The addition of adulterations; honey, glycerin and other flavors in the process of preparing the flavored (Mua'sel) tobacco contributes to lowering the nicotine content in each gram of flavored tobacco. Smoking one head of flavored (Mua'sel) tobacco which contains on average one third of nicotine presented in 20 cigarettes (204mg/pack) usually resulted in a higher plasma nicotine level by 20%. Conclusion: Hubble-bubble smokers are not at a lesser risk from smoking than cigarette smokers in relation to nicotine dependence. The inability of water to trap significant amounts of chemical substances present in tobacco (especially nicotine) and the danger which might result from the combustion of additives like; glycerin, honey and other flavors could be a very important factor to extrapolate the damage resulting from HB smoking. Descriptors flavoring agent, glycerol, nicotine, article, blood level, chemical analysis, chemical composition, smoking, clinical laboratory, combustion, controlled study, flavor, gas chromatography, honey, Jordan, risk assessment, tobacco dependence, toxicology, university Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Hadidi,K. A., Mohammed,F. I. Original/Translated Title URL Date of Electronic PMCID Editors
Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness?	2004	Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway. ulrik.wisloff@medisin.ntnu.no	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of physiology Periodical, Abbrev. J.Physiol. Pub Date Free Form 16-Mar Volume 555 Issue Pt 3 Start Page 825 Other Pages 829 Notes LR: 20140610; JID: 0266262; 0 (Nitric Oxide Donors); 16051-77-7 (isosorbide-5-mononitrate); 31C4KY9ESH (Nitric Oxide); IA7306519N (Isosorbide Dinitrate); OID: NLM: PMC1664873; 2004/01/14 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 0022-3751; 0022-3751 Accession Number PMID: 14724207 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1113/jphysiol.2003.055467 [doi] Output Language Unknown(0) PMID 14724207 Abstract Nitrogen dissolves in the blood during dives, but comes out of solution if divers return to normal pressure too rapidly. Nitrogen bubbles cause a range of effects from skin rashes to seizures, coma and death. It is believed that these bubbles form from bubble precursors (gas nuclei). Recently we have shown that a single bout of exercise 20 h, but not 48 h, before a simulated dive prevents bubble formation and protects rats from severe decompression sickness (DCS) and death. Furthermore, we demonstrated that administration of N(omega)-nitro-l-arginine methyl ester, a non-selective inhibitor of NO synthase (NOS), turns a dive from safe to unsafe in sedentary but not exercised rats. Therefore based upon previous data an attractive hypothesis is that it may be possible to use either exercise or NO-releasing agents before a dive to inhibit bubble formation and thus protect against DCS. Consequently, the aims of the present study were to determine whether protection against bubble formation in 'diving' rats was provided by (1) chronic and acute administration of a NO-releasing agent and (2) exercise less than 20 h prior to the dive. NO given for 5 days and then 20 h prior to a dive to 700 kPa lasting 45 min breathing air significantly reduced bubble formation and prevented death. The same effect was seen if NO was given only 30 min before the dive. Exercise 20 h before a dive suppressed bubble formation and prevented death, with no effect at any other time (48, 10, 5 and 0.5 h prior to the dive). Pre-dive activities have not been considered to influence the growth of bubbles and thus the risk of serious DCS. The present novel findings of a protective effect against bubble formation and death by appropriately timed exercise and an NO-releasing agent may form the basis of a new approach to preventing serious decompression sickness. Descriptors Animals, Decompression Sickness/prevention & control, Diving, Female, Isosorbide Dinitrate/analogs & derivatives/pharmacology, Motor Activity/physiology, Nitric Oxide/physiology, Nitric Oxide Donors/pharmacology, Rats, Rats, Sprague-Dawley Links Book Title Database Publisher Data Source Authors Wisloff,U., Richardson,R. S., Brubakk,A. O. Original/Translated Title URL Date of Electronic 20040114 PMCID PMC1664873 Editors
Knowledge, attitudes, and practices of argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in Lebanon	2004	Chaaya, M., Dept. of Epidemiol. and Pop. Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addictive Behaviors Periodical, Abbrev. Addict.Behav. Pub Date Free Form / Volume 29 Issue 9 Start Page 1821 Other Pages 1831 Notes Place of Publication ISSN/ISBN 0306-4603 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Background: Currently, little is known about argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in the Arab world, despite emerging evidence on the adverse health effects of argileh smoking and well-established knowledge about the health risks of cigarette smoking during pregnancy. Objectives: The present study assesses pregnant Arab women's knowledge of chemical contents and related harmful effects of argileh and cigarettes, their attitudes towards smoking argileh and cigarettes, and their actual smoking of argileh and cigarettes, both before and during pregnancy. Methods: A stratified sample of 864 women from 23 health care centers in Lebanon completed a structured, interviewer-administered questionnaire. Information was collected on basic demographic variables, women's knowledge, attitudes, and cigarette and argileh smoking. Results: Women were partially knowledgeable about the health risks of cigarette smoking, knew little about the harmful ingredients of argileh smoking, and had many misconceptions regarding how argileh worked or how it can produce harm. Attitudes were permissive towards all forms of smoking. Almost one quarter (23%) of participants reported smoking during pregnancy, with 17% smoking only cigarettes, 4% smoking only argileh, and 1.5% smoking both cigarette and argileh. Conclusion: A significant and growing percentage of pregnant Arab women are smoking in Lebanon, with four cigarette smokers for every argileh smoker. Smoking behaviors are empirically linked with important gaps in knowledge and with permissive attitudes. These data may be used to design more effective prevention programs targeting this vulnerable population. Â© 2004 Elsevier Ltd. All rights reserved. Descriptors adult, article, attitude, behavior, smoking, controlled study, demography, female, human, Lebanon, pregnancy Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Chaaya,M., Jabbour,S., El-Roueiheb,Z., Chemaitelly,H. Original/Translated Title URL Date of Electronic PMCID Editors
Nargile (Hubble-Bubble) smoking-induced hand eczema	2002	Onder, M., Ankara, Turkey	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of dermatology Periodical, Abbrev. Int.J.Dermatol. Pub Date Free Form 2002/11 Volume 41 Issue 11 Start Page 771 Other Pages 772 Notes Place of Publication ISSN/ISBN 0011-9059 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors corticosteroid, urea, aged, anamnesis, article, case report, clinical examination, diagnostic test, differential diagnosis, finger nail, hand eczema, hand injury, hand palm, human, index finger, palmoplantar keratoderma, leisure, microbiological examination, patch test, physical examination, smoking cessation, smoking habit, thumb, yeast Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Onder,M., Oztas,M., Arnavut,O. Original/Translated Title URL Date of Electronic PMCID Editors
Levels of maximum end-expiratory carbon monoxide and certain cardiovascular parameters following hubble-bubble smoking	2002	Shafagoj, Y.A., Dept. of Physiology and Biochemistry, Faculty of Medicine, University of Jordan, Amman 11942, Jordan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Saudi medical journal Periodical, Abbrev. Saudi Med.J. Pub Date Free Form 2002/08 Volume 23 Issue 8 Start Page 953 Other Pages 958 Notes Place of Publication ISSN/ISBN 0379-5284 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objective: The physiological effects of cigarette smoking have been widely studied, however, little is known regarding the effects of smoking hubble-bubble. We examined the acute effects of hubble-bubble smoking on heart rate, systolic, diastolic, and mean arterial blood pressure and maximum end-expiratory carbon monoxide. Methods: This study was carried out in, in the student laboratory, School of Medicine, Department of Physiology, University of Jordan, Amman, Jordan, during the summer of 1999. In 18 healthy habitual hubble-bubble smokers, heart rate, blood pressure, and maximum end-expiratory carbon monoxide was measured before, during and post smoking of one hubble-bubble run (45 minutes). Results: Compared to base line (time zero), at the end of smoking heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, and maximum end-expiratory carbon monoxide were increased 16 Â± 2.4 beats per minute, 6.7 Â± 2.5 mm Hg, 4.4 Â± 1.6 mm Hg, 5.2 Â± 1.7 mm Hg, and 14.2 Â± 1.8 ppm, (mean Â± standard error of mean, P<.05). Conclusions: Acute short-term active hubble-bubble smoking elicits a modest increase in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure and maximum end-expiratory carbon monoxide in healthy hubble-bubble smokers. Descriptors carbon monoxide, adult, article, blood pressure, cardiovascular parameters, controlled study, diastolic blood pressure, heart rate, human, human experiment, Jordan, laboratory, male, mean arterial pressure, normal human, smoking, summer, systolic blood pressure, university Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Shafagoj,Y. A., Mohammed,F. I. Original/Translated Title URL Date of Electronic PMCID Editors
Hubble-bubble (water pipe) smoking: Levels of nicotine and cotinine in plasma, saliva and urine	2002	Shafagoj, Y.A., Dept. of Physiology/Biochemistry, Faculty of Medicine, University of Jordan, Amman 11942, Jordan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of clinical pharmacology and therapeutics Periodical, Abbrev. Int.J.Clin.Pharmacol.Ther. Pub Date Free Form 2002/ Volume 40 Issue 6 Start Page 249 Other Pages 255 Notes Place of Publication ISSN/ISBN 0946-1965 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objectives: The purpose of the present study was to assess the levels of nicotine and cotinine in biological fluids (plasma, saliva, and urine) following hubble-bubble (HB) smoking. Methods: Fourteen healthy male volunteers, aged 28 Â± 8 years, body weight of 82.7 Â± 13.53 kg, participated in the study. All volunteers were habitual HB smokers for 3.29 Â± 1.90 years who smoked at least 3 runs per week with an average of 20 g Mua'sel per run. Volunteers were requested to avoid smoking, at least 84 hours prior to the time of the study. After baseline samples were taken, volunteers started smoking 20 g of Mua'sel for a period of 45 minutes. Heparinized blood samples (5 or 10 ml each) were drawn for nicotine and cotinine analysis before, during and after the smoking period. Saliva samples were collected just before smoking (time 0) and at the end of smoking (45 min). Urine also was collected at time 0 and 24-hour urine collection was also taken to measure nicotine and cotinine excretion. Nicotine and cotinine were extracted from samples and assayed by gas chromatography. All data are presented as mean Â± SEM throughout the text, Tables and Figures unless indicated otherwise. Results: Plasma nicotine levels rose from 1.11 Â± 0.62 ng/ml at baseline to a maximum of 60.31 Â± 7.58 ng/ml (p <0.001) at the end of smoking (45 min). Plasma cotinine levels increased from 0.79 Â± 0.79 ng/ml at baseline to its highest concentration of 51.95 Â± 13.58 ng/ml (p < 0.001) 3 hours following the end of smoking. Saliva nicotine levels significantly rose from 1.05 Â± 0.72 to 624.74 Â± 149.3 ng/ml and also saliva cotinine levels significantly increased from 0.79 Â± 0.79 ng/ml to 283.49 Â± 75.04 ng/ml. Mean amounts of nicotine and cotinine excreted in urine during the 24-hour urine collection following smoking were equal to 73.59 Â± 18.28 and 249 Â± 54.78 Î¼g, respectively. Conclusion: Following a single run of HB smoking, plasma, saliva and urinary nicotine and cotinine concentration increased to high values. This observation suggests that HB may not be an innocent habit, as people believe. Descriptors cotinine, heparin, nicotine, adult, article, blood analysis, blood level, body fluid, body weight, controlled study, gas chromatography, human, male, normal human, saliva level, smoking, smoking cessation, tobacco, urinalysis, urinary excretion, urine level, volunteer Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Shafagoj,Y. A., Mohammed,F. I., Hadidi,K. A. Original/Translated Title URL Date of Electronic PMCID Editors
Ascent rate, age, maximal oxygen uptake, adiposity, and circulating venous bubbles after diving	2002	Faculte des Sciences du Sport, Luminy, 13009 Marseille, France. carturan@wanadoo.fr	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of applied physiology (Bethesda, Md.: 1985) Periodical, Abbrev. J.Appl.Physiol.(1985) Pub Date Free Form Oct Volume 93 Issue 4 Start Page 1349 Other Pages 1356 Notes LR: 20130926; JID: 8502536; ppublish Place of Publication United States ISSN/ISBN 8750-7587; 0161-7567 Accession Number PMID: 12235035 Language eng SubFile Journal Article; IM DOI 10.1152/japplphysiol.00723.1999 [doi] Output Language Unknown(0) PMID 12235035 Abstract Decompression sickness in diving is recognized as a multifactorial phenomenon, depending on several factors, such as decompression rate and individual susceptibility. The Doppler ultrasonic detection of circulating venous bubbles after diving is considered a useful index for the safety of decompression because of the relationship between bubbles and decompression sickness risk. The aim of this study was to assess the effects of ascent rate, age, maximal oxygen uptake (VO(2 max)), and percent body fat on the production of bubbles after diving. Fifty male recreational divers performed two dives at 35 m during 25 min and then ascended in one case at 9 m/min and in the other case at 17 m/min. They performed the same decompression stops in the two cases. Twenty-eight divers were Doppler monitored at 10-min intervals, until 60 min after surfacing, and the data were analyzed by Wilcoxon signed-rank test to compare the effect of ascent rate on the kinetics of bubbles. Twenty-two divers were monitored 60 min after surfacing. The effect on bubble production 60 min after surfacing of the four variables was studied in 47 divers. The data were analyzed by multinomial log-linear model. The analysis showed that the 17 m/min ascent produced more elevated grades of bubbles than the 9 m/min ascent (P < 0.05), except at the 40-min interval, and showed relationships between grades of bubbles and ascent rate and age and interaction terms between VO(2 max) and age, as well as VO(2 max) and percent body fat. Younger, slimmer, or aerobically fitter divers produced fewer bubbles compared with older, fatter, or poorly physically fit divers. These findings and the conclusions of previous studies performed on animals and humans led us to support that ascent rate, age, aerobic fitness, and adiposity are factors of susceptibility for bubble formation after diving. Descriptors Adipose Tissue/anatomy & histology, Adult, Aging/physiology, Decompression, Diving/adverse effects, Embolism, Air/etiology, Humans, Kinetics, Male, Middle Aged, Oxygen Consumption, Time Factors, Ultrasonography, Doppler Links Book Title Database Publisher Data Source Authors Carturan,D., Boussuges,A., Vanuxem,P., Bar-Hen,A., Burnet,H., Gardette,B. Original/Translated Title URL Date of Electronic PMCID Editors
Arteriovenous bubbles following cold water sport dives: relation to right-to-left shunting	2000	Department of Neurology, Justus-Liebig-University, Giessen, Germany.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Neurology Periodical, Abbrev. Neurology Pub Date Free Form 12-Dec Volume 55 Issue 11 Start Page 1741 Other Pages 1743 Notes LR: 20081121; JID: 0401060; ppublish Place of Publication UNITED STATES ISSN/ISBN 0028-3878; 0028-3878 Accession Number PMID: 11113236 Language eng SubFile Journal Article; AIM; IM DOI Output Language Unknown(0) PMID 11113236 Abstract Neurologic injury subsequent to decompression from diving may be due to paradoxical arterialization of venous gas emboli. Of 40 divers who performed 53 open water dives after being tested for a patent foramen ovale (PFO), arterial gas emboli were detected in 7 of 13 dives, which resulted in venous bubbles. In five of these seven dives, there was evidence of a PFO by contrast transcranial Doppler sonography, indicating an increased risk of arterializing venous bubbles in divers with a PFO. Descriptors Adult, Cold Temperature/adverse effects, Decompression Sickness, Diving, Embolism, Air/physiopathology/ultrasonography, Female, Humans, Male, Middle Aged, Ultrasonography, Doppler Links Book Title Database Publisher Data Source Authors Gerriets,T., Tetzlaff,K., Liceni,T., Schafer,C., Rosengarten,B., Kopiske,G., Algermissen,C., Struck,N., Kaps,M. Original/Translated Title URL Date of Electronic PMCID Editors
Narghile (hubble-bubble) smoking, low birth weight, and other pregnancy outcomes	1998	Nuwayhid, I.A., American University of Beirut, New York, NY 10022, United States	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full American Journal of Epidemiology Periodical, Abbrev. Am.J.Epidemiol. Pub Date Free Form 1998/08 Volume 148 Issue 4 Start Page 375 Other Pages 383 Notes Place of Publication ISSN/ISBN 0002-9262 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Narghile smoking, a common habit among women in many non-Western societies, is assumed by the public to be minimally harmful. This study aims at identifying the effect of smoking narghiles during pregnancy on the weight of the newborn and other pregnancy outcomes. Three groups of pregnant women were interviewed in several hospitals in Lebanon between 1993 and 1995: 106 who smoked narghiles during their pregnancy, 277 who smoked cigarettes, and 512 who did not smoke. The adjusted mean birth weight of babies born to women who smoked one or more narghiles a day during pregnancy and to women who started smoking in the first trimester was more than 100 g less than that of babies born to nonsmokers (p < 0.1). The adjusted odds ratio of having babies with low birth weight (<2,500 g) among the narghile smokers was 1.89 (95% confidence interval (CI) 0.67-5.38). The risk increased to 2.62 (95% CI 0.90- 7.66) among those who started smoking narghiles in the first trimester. A stronger association and a dose-response relation were found among cigarette smokers. The association between narghile smoking and other pregnancy outcomes, especially Apgar score and respiratory distress, was also noticeable. Further research and a policy action to fight the misperception that narghile smoking is safe are both recommended. Descriptors adult, Apgar score, article, controlled study, female, fetus outcome, human, Lebanon, low birth weight, major clinical study, respiratory distress, risk assessment, risk factor, smoking Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Nuwayhid,I. A., Yamout,B., Azar,G., Kambris,M. A. K. Original/Translated Title URL Date of Electronic PMCID Editors
Arterial gas bubbles after decompression in pigs with patent foramen ovale	1993	Section for Extreme Work Environment, Sintef Unimed, Trondheim, Norway.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc Periodical, Abbrev. Undersea Hyperb.Med. Pub Date Free Form Jun Volume 20 Issue 2 Start Page 121 Other Pages 131 Notes LR: 20071115; JID: 9312954; 0 (Gases); ppublish Place of Publication UNITED STATES ISSN/ISBN 1066-2936; 1066-2936 Accession Number PMID: 8329939 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM; S DOI Output Language Unknown(0) PMID 8329939 Abstract With patent foramen ovale (PFO), thought to be a risk factor for some forms of DCS, venous bubbles may pass through the patent opening to become arterial bubbles. We exposed 14 anesthetized, spontaneously breathing pigs to air at 5 bar (500 kPa, absolute pressure) for 30 min and then rapidly decompressed at 2 bar/min to 1 bar. We measured intravascular pressures, blood gases, and, with transesophageal echocardiology, bubbles in the pulmonary artery and ascending aorta. Autopsy showed that six of the pigs had a PFO. Arterial bubbles occurred more frequently in the PFO group (in six out of six) than in the non-PFO group (in two out of eight, P < 0.01). When arterial bubbles were detected, the venous bubble count and the pulmonary artery pressure tended to be lower in pigs with PFO than in pigs without a PFO. We conclude that a PFO increases the risk of arterial bubbles after decompression. Descriptors Animals, Atmosphere Exposure Chambers, Decompression Sickness/blood/etiology/physiopathology, Embolism, Air/blood/etiology/physiopathology, Gases/blood, Heart Septal Defects, Atrial/blood/complications/physiopathology, Hemodynamics/physiology, Swine Links Book Title Database Publisher Data Source Authors Vik,A., Jenssen,B. M., Brubakk,A. O. Original/Translated Title URL Date of Electronic PMCID Editors

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