WTS database

Title	Pub Year Sort descending	Author	SearchLink
Hubble-bubble (water pipe) smoking: Levels of nicotine and cotinine in plasma, saliva and urine	2002	Shafagoj, Y.A., Dept. of Physiology/Biochemistry, Faculty of Medicine, University of Jordan, Amman 11942, Jordan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of clinical pharmacology and therapeutics Periodical, Abbrev. Int.J.Clin.Pharmacol.Ther. Pub Date Free Form 2002/ Volume 40 Issue 6 Start Page 249 Other Pages 255 Notes Place of Publication ISSN/ISBN 0946-1965 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objectives: The purpose of the present study was to assess the levels of nicotine and cotinine in biological fluids (plasma, saliva, and urine) following hubble-bubble (HB) smoking. Methods: Fourteen healthy male volunteers, aged 28 Â± 8 years, body weight of 82.7 Â± 13.53 kg, participated in the study. All volunteers were habitual HB smokers for 3.29 Â± 1.90 years who smoked at least 3 runs per week with an average of 20 g Mua'sel per run. Volunteers were requested to avoid smoking, at least 84 hours prior to the time of the study. After baseline samples were taken, volunteers started smoking 20 g of Mua'sel for a period of 45 minutes. Heparinized blood samples (5 or 10 ml each) were drawn for nicotine and cotinine analysis before, during and after the smoking period. Saliva samples were collected just before smoking (time 0) and at the end of smoking (45 min). Urine also was collected at time 0 and 24-hour urine collection was also taken to measure nicotine and cotinine excretion. Nicotine and cotinine were extracted from samples and assayed by gas chromatography. All data are presented as mean Â± SEM throughout the text, Tables and Figures unless indicated otherwise. Results: Plasma nicotine levels rose from 1.11 Â± 0.62 ng/ml at baseline to a maximum of 60.31 Â± 7.58 ng/ml (p <0.001) at the end of smoking (45 min). Plasma cotinine levels increased from 0.79 Â± 0.79 ng/ml at baseline to its highest concentration of 51.95 Â± 13.58 ng/ml (p < 0.001) 3 hours following the end of smoking. Saliva nicotine levels significantly rose from 1.05 Â± 0.72 to 624.74 Â± 149.3 ng/ml and also saliva cotinine levels significantly increased from 0.79 Â± 0.79 ng/ml to 283.49 Â± 75.04 ng/ml. Mean amounts of nicotine and cotinine excreted in urine during the 24-hour urine collection following smoking were equal to 73.59 Â± 18.28 and 249 Â± 54.78 Î¼g, respectively. Conclusion: Following a single run of HB smoking, plasma, saliva and urinary nicotine and cotinine concentration increased to high values. This observation suggests that HB may not be an innocent habit, as people believe. Descriptors cotinine, heparin, nicotine, adult, article, blood analysis, blood level, body fluid, body weight, controlled study, gas chromatography, human, male, normal human, saliva level, smoking, smoking cessation, tobacco, urinalysis, urinary excretion, urine level, volunteer Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Shafagoj,Y. A., Mohammed,F. I., Hadidi,K. A. Original/Translated Title URL Date of Electronic PMCID Editors
Nargile (Hubble-Bubble) smoking-induced hand eczema	2002	Onder, M., Ankara, Turkey	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full International journal of dermatology Periodical, Abbrev. Int.J.Dermatol. Pub Date Free Form 2002/11 Volume 41 Issue 11 Start Page 771 Other Pages 772 Notes Place of Publication ISSN/ISBN 0011-9059 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Descriptors corticosteroid, urea, aged, anamnesis, article, case report, clinical examination, diagnostic test, differential diagnosis, finger nail, hand eczema, hand injury, hand palm, human, index finger, palmoplantar keratoderma, leisure, microbiological examination, patch test, physical examination, smoking cessation, smoking habit, thumb, yeast Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Onder,M., Oztas,M., Arnavut,O. Original/Translated Title URL Date of Electronic PMCID Editors
Knowledge, attitudes, and practices of argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in Lebanon	2004	Chaaya, M., Dept. of Epidemiol. and Pop. Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Addictive Behaviors Periodical, Abbrev. Addict.Behav. Pub Date Free Form / Volume 29 Issue 9 Start Page 1821 Other Pages 1831 Notes Place of Publication ISSN/ISBN 0306-4603 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Background: Currently, little is known about argileh (water pipe or hubble-bubble) and cigarette smoking among pregnant women in the Arab world, despite emerging evidence on the adverse health effects of argileh smoking and well-established knowledge about the health risks of cigarette smoking during pregnancy. Objectives: The present study assesses pregnant Arab women's knowledge of chemical contents and related harmful effects of argileh and cigarettes, their attitudes towards smoking argileh and cigarettes, and their actual smoking of argileh and cigarettes, both before and during pregnancy. Methods: A stratified sample of 864 women from 23 health care centers in Lebanon completed a structured, interviewer-administered questionnaire. Information was collected on basic demographic variables, women's knowledge, attitudes, and cigarette and argileh smoking. Results: Women were partially knowledgeable about the health risks of cigarette smoking, knew little about the harmful ingredients of argileh smoking, and had many misconceptions regarding how argileh worked or how it can produce harm. Attitudes were permissive towards all forms of smoking. Almost one quarter (23%) of participants reported smoking during pregnancy, with 17% smoking only cigarettes, 4% smoking only argileh, and 1.5% smoking both cigarette and argileh. Conclusion: A significant and growing percentage of pregnant Arab women are smoking in Lebanon, with four cigarette smokers for every argileh smoker. Smoking behaviors are empirically linked with important gaps in knowledge and with permissive attitudes. These data may be used to design more effective prevention programs targeting this vulnerable population. Â© 2004 Elsevier Ltd. All rights reserved. Descriptors adult, article, attitude, behavior, smoking, controlled study, demography, female, human, Lebanon, pregnancy Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Chaaya,M., Jabbour,S., El-Roueiheb,Z., Chemaitelly,H. Original/Translated Title URL Date of Electronic PMCID Editors
Nicotine content in tobacco used in hubble-bubble smoking	2004	Hadidi, K.A., Forensic Med./Toxicology Division, Faculty of Medicine, University of Jordan, Amman 11942, Jordan	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Saudi medical journal Periodical, Abbrev. Saudi Med.J. Pub Date Free Form / Volume 25 Issue 7 Start Page 912 Other Pages 917 Notes Place of Publication ISSN/ISBN 0379-5284 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objective: To determine the nicotine content of commonly used tobacco in hubble-bubble (HB) and compare it with that found in cigarettes. Methods: Analysis of nicotine content of 13 commercial brands of HB tobacco was carried out using gas chromatography over an 8 month period; November 2002 through to June 2003 at the Toxicology Laboratory, University of Jordan. Results: A wide variation in nicotine content in all brands was noticed with an average of 8.32 mg/g tobacco, range (1.8-44.3 mg/g). The average nicotine content in each HB head (20 gm) of unflavored tobacco was (713mg/head) and flavored tobacco has (67mg/head). One head of unflavored tobacco has nicotine equivalent to 70 regular cigarettes. The addition of adulterations; honey, glycerin and other flavors in the process of preparing the flavored (Mua'sel) tobacco contributes to lowering the nicotine content in each gram of flavored tobacco. Smoking one head of flavored (Mua'sel) tobacco which contains on average one third of nicotine presented in 20 cigarettes (204mg/pack) usually resulted in a higher plasma nicotine level by 20%. Conclusion: Hubble-bubble smokers are not at a lesser risk from smoking than cigarette smokers in relation to nicotine dependence. The inability of water to trap significant amounts of chemical substances present in tobacco (especially nicotine) and the danger which might result from the combustion of additives like; glycerin, honey and other flavors could be a very important factor to extrapolate the damage resulting from HB smoking. Descriptors flavoring agent, glycerol, nicotine, article, blood level, chemical analysis, chemical composition, smoking, clinical laboratory, combustion, controlled study, flavor, gas chromatography, honey, Jordan, risk assessment, tobacco dependence, toxicology, university Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Hadidi,K. A., Mohammed,F. I. Original/Translated Title URL Date of Electronic PMCID Editors
A deep stop during decompression from 82 fsw (25 m) significantly reduces bubbles and fast tissue gas tensions	2004	DAN Europe Foundation, Research Division.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc Periodical, Abbrev. Undersea Hyperb.Med. Pub Date Free Form Summer Volume 31 Issue 2 Start Page 233 Other Pages 243 Notes LR: 20050627; JID: 9312954; CIN: Undersea Hyperb Med. 2005 Mar-Apr;32(2):85-8; author reply 89-92. PMID: 15926299; ppublish Place of Publication United States ISSN/ISBN 1066-2936; 1066-2936 Accession Number PMID: 15485086 Language eng SubFile Evaluation Studies; Journal Article; IM; S DOI Output Language Unknown(0) PMID 15485086 Abstract In spite of many modifications to decompression algorithms, the incidence of decompression sickness (DCS) in scuba divers has changed very little. The success of stage, compared to linear ascents, is well described yet theoretical changes in decompression ratios have diminished the importance of fast tissue gas tensions as critical for bubble generation. The most serious signs and symptoms of DCS involve the spinal cord, with a tissue half time of only 12.5 minutes. It is proposed that present decompression schedules do not permit sufficient gas elimination from such fast tissues, resulting in bubble formation. Further, it is hypothesized that introduction of a deep stop will significantly reduce fast tissue bubble formation and neurological DCS risk. A total of 181 dives were made to 82 fsw (25 m) by 22 volunteers. Two dives of 25 min and 20 min were made, with a 3 hr 30 min surface interval and according to 8 different ascent protocols. Ascent rates of 10, 33 or 60 fsw/min (3, 10, 18 m/min) were combined with no stops or a shallow stop at 20 fsw (6 m) or a deep stop at 50 fsw (15 m) and a shallow at 20 fsw (6 m). The highest bubbles scores (8.78/9.97), using the Spencer Scale (SS) and Extended Spencer Scale (ESS) respectively, were with the slowest ascent rate. This also showed the highest 5 min and 10 min tissue loads of 48% and 75%. The lowest bubble scores (1.79/2.50) were with an ascent rate of 33 fsw (10 m/min) and stops for 5 min at 50 fsw (15 m) and 20 fsw (6 m). This also showed the lowest 5 and 10 min tissue loads at 25% and 52% respectively. Thus, introduction of a deep stop significantly reduced Doppler detected bubbles together with tissue gas tensions in the 5 and 10 min tissues, which has implications for reducing the incidence of neurological DCS in divers. Descriptors Atmospheric Pressure, Decompression/standards, Decompression Sickness/prevention & control/ultrasonography, Diving/adverse effects/standards, Humans, Reference Values, Regression Analysis, Time Factors Links Book Title Database Publisher Data Source Authors Marroni,A., Bennett,P. B., Cronje,F. J., Cali-Corleo,R., Germonpre,P., Pieri,M., Bonuccelli,C., Balestra,C. Original/Translated Title URL Date of Electronic PMCID Editors
Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness?	2004	Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway. ulrik.wisloff@medisin.ntnu.no	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full The Journal of physiology Periodical, Abbrev. J.Physiol. Pub Date Free Form 16-Mar Volume 555 Issue Pt 3 Start Page 825 Other Pages 829 Notes LR: 20140610; JID: 0266262; 0 (Nitric Oxide Donors); 16051-77-7 (isosorbide-5-mononitrate); 31C4KY9ESH (Nitric Oxide); IA7306519N (Isosorbide Dinitrate); OID: NLM: PMC1664873; 2004/01/14 [aheadofprint]; ppublish Place of Publication England ISSN/ISBN 0022-3751; 0022-3751 Accession Number PMID: 14724207 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM DOI 10.1113/jphysiol.2003.055467 [doi] Output Language Unknown(0) PMID 14724207 Abstract Nitrogen dissolves in the blood during dives, but comes out of solution if divers return to normal pressure too rapidly. Nitrogen bubbles cause a range of effects from skin rashes to seizures, coma and death. It is believed that these bubbles form from bubble precursors (gas nuclei). Recently we have shown that a single bout of exercise 20 h, but not 48 h, before a simulated dive prevents bubble formation and protects rats from severe decompression sickness (DCS) and death. Furthermore, we demonstrated that administration of N(omega)-nitro-l-arginine methyl ester, a non-selective inhibitor of NO synthase (NOS), turns a dive from safe to unsafe in sedentary but not exercised rats. Therefore based upon previous data an attractive hypothesis is that it may be possible to use either exercise or NO-releasing agents before a dive to inhibit bubble formation and thus protect against DCS. Consequently, the aims of the present study were to determine whether protection against bubble formation in 'diving' rats was provided by (1) chronic and acute administration of a NO-releasing agent and (2) exercise less than 20 h prior to the dive. NO given for 5 days and then 20 h prior to a dive to 700 kPa lasting 45 min breathing air significantly reduced bubble formation and prevented death. The same effect was seen if NO was given only 30 min before the dive. Exercise 20 h before a dive suppressed bubble formation and prevented death, with no effect at any other time (48, 10, 5 and 0.5 h prior to the dive). Pre-dive activities have not been considered to influence the growth of bubbles and thus the risk of serious DCS. The present novel findings of a protective effect against bubble formation and death by appropriately timed exercise and an NO-releasing agent may form the basis of a new approach to preventing serious decompression sickness. Descriptors Animals, Decompression Sickness/prevention & control, Diving, Female, Isosorbide Dinitrate/analogs & derivatives/pharmacology, Motor Activity/physiology, Nitric Oxide/physiology, Nitric Oxide Donors/pharmacology, Rats, Rats, Sprague-Dawley Links Book Title Database Publisher Data Source Authors Wisloff,U., Richardson,R. S., Brubakk,A. O. Original/Translated Title URL Date of Electronic 20040114 PMCID PMC1664873 Editors
Knowledge, attitude and believes of Nargila (hubble-bubble) smoking in Iraq	2005		Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Journal of the Bahrain Medical Society Periodical, Abbrev. J.Bahrain Med.Soc. Pub Date Free Form 2005/04 Volume 17 Issue 2 Start Page 128 Other Pages 134 Notes Place of Publication ISSN/ISBN 1015-6321 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Aim: To study the knowledge, attitude and practice of smoking Nargila. Methods: Cross-sectional study of 200 male smokers from different parts of Iraq. Results: The study showed that the highest rate was among youth aged 20-39 years and negatively correlated with the level of education. The cost ranged between 250-15,000 ID per weak and the average time spent for each smoking was 30 minutes. The study revealed that 90% of the sample prefer Nargila smoking than cigarette, because they believed it is less harmful, due to passage of smoke through water, and more enjoyable. Less than 10% used a disposable tip while the rest shared the same tip with their friends and even with worker responsible for preparing Nargilas. Moreover, about half of the sample declared that they were unwilling to quit from the habit. A Preliminary test of especially manufactured smoking machine showed that the amount of tar and nicotine precipitated from the Nargila smoke might be more than that expected and that declared by manufacturers. Conclusions: The study pointed out the importance of changing the wrong belives knowledge towards Nargila and arrange a suitable health education programme to highlight its harmful effect on the health of smokers. Descriptors nicotine, tar, academic achievement, adult, age distribution, article, attitude, health education, human, Iraq, male, normal human, smoking Links Book Title Database Embase Publisher Data Source Embase Authors Al-Dabbagh,S., Al-Sinjari,K. M. Original/Translated Title URL Date of Electronic PMCID Editors
Venous bubble count declines during strenuous exercise after an open sea dive to 30 m	2006	Department of Physiology, University of Split School of Medicine, Croatia. zdujic@bsb.mefst.hr	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Aviation, Space, and Environmental Medicine Periodical, Abbrev. Aviat.Space Environ.Med. Pub Date Free Form Jun Volume 77 Issue 6 Start Page 592 Other Pages 596 Notes LR: 20061115; JID: 7501714; 0 (Gases); ppublish Place of Publication United States ISSN/ISBN 0095-6562; 0095-6562 Accession Number PMID: 16780236 Language eng SubFile Journal Article; Research Support, Non-U.S. Gov't; IM; S DOI Output Language Unknown(0) PMID 16780236 Abstract INTRODUCTION: The effect of post-dive exercise on bubble formation remains controversial, although the current practice of divers and aviators is to avoid strenuous exercise after diving. Previously, we have shown that exercising 24 h before a dive, or during a decompression stop, significantly reduces bubble formation in man. The objective of this study was to determine whether a short period of strenuous post-dive exercise promotes venous bubble formation. METHODS: Seven male military divers performed an open-sea field dive to a maximum depth of 30 m for 30 min. At maximum depth, subjects performed mild underwater fin swimming, followed by standard decompression. Diving was followed by a post-dive exercise session consisting of short, strenuous incremental upright cycle ergometry, up to 85% of maximal oxygen uptake, for about 10 min. Subjects were monitored for venous gas bubbles in the right heart with an echo-imaging system starting 20 min post-dive while in the supine position, during cycle ergometry in the seated upright position, and immediately after exercise in a supine position. RESULTS: The average number of bubbles was 1.5 +/- 1.4 bubbles x cm(-2) 20 min after diving. Changes in posture from supine to seated upright resulted in significant reduction of bubbles to 0.6 +/- 1.3 bubbles x cm(-2) (p = 0.043), with further reduction to 0.2 +/- 0.3 bubbles x cm(-2) at the end of exercise (p = 0.02). No cases of DCS or intra-pulmonary shunt were observed during or following post-dive exercise. DISCUSSION: These results suggest that post-dive strenuous exercise after a single field dive reduces post-dive gas bubble formation in well-trained military divers. Additional findings are needed for normal sports divers. Descriptors Adult, Decompression Sickness/prevention & control, Diving/physiology, Exercise/physiology, Gases/blood, Humans, Male, Military Medicine, Statistics, Nonparametric, Veins Links Book Title Database Publisher Data Source Authors Dujic,Z., Obad,A., Palada,I., Ivancev,V., Valic,Z. Original/Translated Title URL Date of Electronic PMCID Editors
Hubble bubble equals trouble: the hazards of water pipe smoking.	2006	Urkin, J., Primary Pediatric Unit, Faculty of Health Sciences, Ben-Gurion University of theNegev, Beer-Sheva, Israel.	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full TheScientificWorldJournal Periodical, Abbrev. ScientificWorldJournal Pub Date Free Form / Volume 6 Issue Start Page 1990 Other Pages 1997 Notes Place of Publication ISSN/ISBN 1537-744X Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract A Narghile, one of the names for a water pipe, is an instrument for tobacco smoking that has became a trend among the youth in Israel. The mistaken opinion that smoking a Narghile is not as dangerous as smoking cigarettes makes the youngsters and their parents take it lightly and contributes to the expansion of its use. The objective of this paper was to review the literature on the health risks of Narghile smoking. A literature search of Medline (PubMed) and the Internet on the health hazards of Narghile smoking was conducted. The health hazards that the Narghile smoker is exposed to include interference with oxidation, damage to genetic compounds, increased risk of developing malignancies, infectious diseases, damage to the fetus and newborn, and exposure to commonly abused chemicals. It is concluded that increased awareness of the expanded use of the Narghile is imperative and education programs about the prevention of cigarette smoking and substance abuse should also include Narghile smoking. Descriptors adolescent, child behavior, human, psychological aspect, review, smoking, tobacco dependence Links Book Title Database MEDLINE Publisher Data Source Embase Authors Urkin,J., Ochaion,R., Peleg,A. Original/Translated Title URL Date of Electronic PMCID Editors
Comparative analysis of the effects of hubble-bubble (Sheesha) and cigarette smoking on respiratory and metabolic parameters in hubble-bubble and cigarette smokers	2006	Al Mutairi, S.S., Department of Medicine, Faculty of Medicine, Safat 13110, Kuwait	Read more...
Source Type Print(0) Ref Type Journal Article Periodical, Full Respirology Periodical, Abbrev. Respirology Pub Date Free Form / Volume 11 Issue 4 Start Page 449 Other Pages 455 Notes Place of Publication ISSN/ISBN 1323-7799; 1440-1843 Accession Number Language SubFile DOI Output Language Unknown(0) PMID Abstract Objectives and background: Hazard of smoking tobacco is believed to be minimized by smoking hubble-bubble (HB) instead of cigarettes. Our aims were to (i) develop an assay for estimating nicotine and cotinine; and (ii) evaluate the effect of smoking on respiratory and metabolic parameters in cigarette and HB smokers. Methods: Urine samples were collected from 152 volunteer smokers (75 cigarette and 77 HB) as well as from 16 healthy controls. We optimized an HPLC method for the determination of nicotine and cotinine. Subjects were asked to complete a chronic respiratory symptoms questionnaire and to undergo spirometry. Fasting blood samples were collected for the determination of their lipid profile. Results: The intra-assay coefficients of variation for nicotine and cotinine were 16.6% and 6.6%, respectively. The mean of cotinine in cigarette smokers (1321.4 ng/mL) was significantly (P = 0.008) higher than the mean cotinine (677.6 ng/mL) in HB smokers. The mean nicotine level in cigarette smokers (1487.3 ng/mL) was significantly (P < 0.0001) higher than the mean nicotine (440.5 ng/mL) in HB smoker. The urinary cotinine and nicotine levels of the control subjects were lower than the detection levels of the assay. The mean high-density lipoprotein cholesterol was lower in cigarette smokers (0.99 mmol/L) compared with HB smoker smokers (1.02 mmol/L) but this was not significant (P = 0.28). Spirometric values were comparable among the three groups but the chronic respiratory symptoms in the smoking groups appeared at an earlier age in the HB smokers compared with the cigarettes smokers (P < 0.05). Conclusion: Smoking HB does not reduce the risk of tobacco exposure and it's potentially harmful metabolites on health. Â© 2006 Asian Pacific Society of Respirology. Descriptors cotinine, glucose, high density lipoprotein cholesterol, low density lipoprotein cholesterol, nicotine, triacylglycerol, adult, aged, analytic method, article, cholesterol blood level, chronic respiratory tract disease, smoking, controlled study, female, glucose blood level, high performance liquid chromatography, human, lipid blood level, lipid metabolism, major clinical study, male, observer variation, priority journal, questionnaire, spirometry, triacylglycerol blood level, urine level Links Book Title Database Embase; MEDLINE Publisher Data Source Embase Authors Al Mutairi,S. S., Shihab-Eldeen,A. A., Mojiminiyi,O. A., Anwar,A. A. Original/Translated Title URL Date of Electronic PMCID Editors

E-mail