Abstract
This US Preventive Services Task Force (USPSTF) report evaluates primary care interventions to prevent and address tobacco use—including e-cigarettes—in children and adolescents under 18, updating its 2013 guidelines amid rising youth vaping rates and persistent smoking risks.
The review confirms that behavioral interventions (e.g., counseling, education, print/computer-based tools) moderately reduce tobacco initiation in youth, with a 18% relative risk reduction in smoking uptake. However, evidence for cessation interventions (behavioral or pharmacological) remains insufficient due to small, underpowered studies—none showing significant quit rates. E-cigarettes, now more common than cigarettes among U.S. teens (27.5% vs. 5.8% in 2019), pose unique risks (nicotine addiction, brain harm, gateway to combustible tobacco). While no medications (e.g., varenicline, NRT) are FDA-approved for youth, behavioral counseling shows no reported harms but lacks proven efficacy for cessation.