The WHO in the Western Pacific Region organized a training session spanning from March 12 to 14, 2024, aimed at enhancing health security capabilities of countries and territories within the region. Over the course of the workshop, delegates from 12 Member States (Cambodia, the Lao People’s Democratic Republic, Malaysia, Mongolia, Palau, the Philippines, Samoa, Tonga, Vanuatu, and Viet Nam) engaged in practical exercises utilizing the NAPHS method. Through this process, they pinpointed the most urgent health security priorities and integrated them into a comprehensive plan for capacity development, complete with cost estimates for execution. The training took into consideration how countries incorporate recommendations from International Health Regulations (2005) (IHR) tools, including: IHR States Parties Self-Assessment Annual Reporting, Joint External Evaluations, IHR-PVS NBW, Strategic Tool for Assessing Risks, simulation exercises and after-action reviews. A dedicated session was held on multisectoral collaboration at the huma-animal-environment interface and how the One Health approach contributes to strengthening Health Security. NBW roadmaps were used as case studies for the group work sessions to support the exercise on the integration of priority actions and recommendations on the various areas addressed under NAPHS.