Journal Article
Print(0)
Antimicrobial Agents and Chemotherapy
Antimicrob.Agents Chemother.
Nov
48
11
4453
4456
LR: 20141120; JID: 0315061; 0 (Antifungal Agents); 0 (Echinocandins); 0 (Peptides, Cyclic); 0 (Pyrimidines); 0 (Triazoles); 7XU7A7DROE (Amphotericin B); 8VZV102JFY (Fluconazole); F0XDI6ZL63 (caspofungin); JFU09I87TR (Voriconazole); OID: NLM: PMC525414; pp
United States
0066-4804; 0066-4804
PMID: 15504881
eng
Journal Article; Research Support, Non-U.S. Gov't; IM
48/11/4453 [pii]
Unknown(0)
15504881
Time-kill and postantifungal effect (PAFE) of amphotericin B, caspofungin, fluconazole, and voriconazole were determined against clinical isolates of Candida guilliermondii, Candida kefyr, and Candida lusitaniae. Azoles displayed fungistatic activity and no measurable PAFE, regardless of the concentration tested. Amphotericin B and caspofungin demonstrated concentration-dependent fungicidal activity, although amphotericin B only produced a significant dose-dependent PAFE against all isolates tested.
Amphotericin B/pharmacology, Antifungal Agents/pharmacology, Candida/drug effects, Candidiasis/complications/microbiology, Colony Count, Microbial, Echinocandins, Fluconazole/pharmacology, Hematologic Neoplasms/complications, Humans, Kinetics, Microbial Sensitivity Tests, Models, Biological, Peptides, Cyclic/pharmacology, Pyrimidines/pharmacology, Triazoles/pharmacology, Voriconazole
Di Bonaventura,G., Spedicato,I., Picciani,C., D'Antonio,D., Piccolomini,R.
Center of Excellence on Aging, Room 27, 5th level, "G. D'Annunzio" University, Via Colle dell'Ara, 66100 Chieti, Italy.
PMC525414
http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=15504881
2004