Journal Article

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Journal of general internal medicine

J.Gen.Intern.Med.

Nov

29

11

1444

1450

LR: 20160701; GR: P30 CA072720/CA/NCI NIH HHS/United States; GR: P30CA072720/CA/NCI NIH HHS/United States; GR: P50 DA036107/DA/NIDA NIH HHS/United States; GR: P50-DA-036105-01/DA/NIDA NIH HHS/United States; GR: P50-DA-036107-01/DA/NIDA NIH HHS/United Stat

United States

1525-1497; 0884-8734

PMID: 24830741

eng

Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; IM

10.1007/s11606-014-2889-7 [doi]

Unknown(0)

24830741

BACKGROUND: Novel nicotine delivery products, such as electronic cigarettes (e-cigarettes), have dramatically grown in popularity despite limited data on safety and benefit. In contrast, the similar U.S. Food and Drug Administration (FDA)-approved nicotine inhaler is rarely utilized by smokers. Understanding this paradox could be helpful to determine the potential for e-cigarettes as an alternative to tobacco smoking. OBJECTIVE: To compare the e-cigarette with the nicotine inhaler in terms of perceived benefits, harms, appeal, and role in assisting with smoking cessation. DESIGN: A cross-over trial was conducted from 2012 to 2013 PARTICIPANTS/INTERVENTIONS: Forty-one current smokers age 18 and older used the e-cigarette and nicotine inhaler each for 3 days, in random order, with a washout period in between. Thirty-eight participants provided data on product use, perceptions, and experiences. MAIN MEASURES: The Modified Cigarette Evaluation Questionnaire (mCEQ) measured satisfaction, reward, and aversion. Subjects were also asked about each product's helpfulness, similarity to cigarettes, acceptability, image, and effectiveness in quitting smoking. Cigarette use was also recorded during the product-use periods. KEY RESULTS: The e-cigarette had a higher total satisfaction score (13.9 vs. 6.8 [p

Steinberg,M.B., Zimmermann,M.H., Delnevo,C.D., Lewis,M.J., Shukla,P., Coups,E.J., Foulds,J.

Rutgers-Robert Wood Johnson Medical School, Division of General Internal Medicine, 125 Paterson Street, Suite 2300, New Brunswick, NJ, 08903, USA, michael.steinberg@rutgers.edu.

20140515

PMC4238186

http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=24830741

2014